KEGG   ORTHOLOGY: K08527Help
Entry
K08527                      KO                                     

Name
RARA, NR1B1
Definition
retinoic acid receptor alpha
Pathway
Th17 cell differentiation
Pathways in cancer
Transcriptional misregulation in cancer
Acute myeloid leukemia
Disease
H00003  
Acute myeloid leukemia (AML)
H00516  
Isolated orofacial clefts
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04659 Th17 cell differentiation
    K08527  RARA, NR1B1; retinoic acid receptor alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08527  RARA, NR1B1; retinoic acid receptor alpha
   05202 Transcriptional misregulation in cancers
    K08527  RARA, NR1B1; retinoic acid receptor alpha
   05221 Acute myeloid leukemia
    K08527  RARA, NR1B1; retinoic acid receptor alpha
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 thyroid hormone-like
    K08527  RARA, NR1B1; retinoic acid receptor alpha
Nuclear receptors [BR:ko03310]
 1. Thyroid hormone like
  1B. Retinoic acid receptor (RAR)
   K08527  RARA, NR1B1; retinoic acid receptor alpha
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5914(RARA)
PTR: 
454647(RARA)
PPS: 
100967548(RARA)
GGO: 
101149605(RARA)
PON: 
NLE: 
100603497(RARA)
MCC: 
700206(RARA)
MCF: 
102132722(RARA)
CSAB: 
103243515(RARA)
RRO: 
104655108(RARA)
RBB: 
108534716(RARA)
CJC: 
100410811(RARA)
SBQ: 
101036514(RARA)
MMU: 
19401(Rara)
RNO: 
24705(Rara)
CGE: 
100771910(Rara)
NGI: 
103731122(Rara)
HGL: 
101722948(Rara)
CCAN: 
109694431(Rara)
OCU: 
100009009(RARA)
TUP: 
102498662(RARA)
CFA: 
480526(RARA)
AML: 
100463678(RARA)
UMR: 
103662226(RARA)
FCA: 
101083048(RARA)
PTG: 
102969575(RARA)
AJU: 
106980526(RARA)
BTA: 
534280(RARA)
BOM: 
102274769(RARA)
BIU: 
109574115(RARA)
PHD: 
102339851(RARA)
CHX: 
102188350(RARA)
OAS: 
101107973(RARA)
SSC: 
396709(RARA)
CFR: 
CDK: 
105099020(RARA)
BACU: 
103009412(RARA)
LVE: 
103082251(RARA)
ECB: 
100054274(RARA)
EPZ: 
103550195(RARA)
EAI: 
106826262(RARA)
MYB: 
102260476(RARA)
MYD: 
102755605(RARA)
HAI: 
109380809(RARA)
RSS: 
109455845(RARA)
PALE: 
102880130(RARA)
LAV: 
100666758(RARA)
MDO: 
100015353(RARA)
SHR: 
100923612(RARA)
GGA: 
395213(RARA)
CJO: 
107325261(RARA)
APLA: 
101792081(RARA)
GFR: 
102041075(RARA)
FAB: 
101814830(RARA)
PHI: 
102111110(RARA)
CCW: 
104697796(RARA)
FPG: 
101912143(RARA)
FCH: 
102055030(RARA)
CLV: 
102092082(RARA)
AAM: 
106486419(RARA)
ASN: 
102387253(RARA)
AMJ: 
102560946(RARA)
PSS: 
102449811(RARA)
CMY: 
102930278(RARA)
CPIC: 
ACS: 
100562365(rara)
PBI: 
103066803(RARA)
GJA: 
107108914(RARA)
XLA: 
XTR: 
100038052(rara)
NPR: 
108795221(RARA)
DRE: 
30680(raraa) 555364(rarab)
SRX: 
SANH: 
SGH: 
IPU: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
SASA: 
ELS: 
SFM: 
108928193(rara)
LCM: 
102356597(RARA)
CMK: 
BFO: 
DPX: 
LAK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2825036
  Authors
Giguere V, Ong ES, Segui P, Evans RM
  Title
Identification of a receptor for the morphogen retinoic acid.
  Journal
Nature 330:624-9 (1987)
DOI:10.1038/330624a0
  Sequence
[hsa:5914]
Reference
  Authors
Parmar S, Tallman MS
  Title
Acute promyelocytic leukaemia:a review.
  Journal
Expert Opin Pharmacother 4:1379-92 (2003)
DOI:10.1517/14656566.4.8.1379
Reference
  Authors
Zelent A, Guidez F, Melnick A, Waxman S, Licht JD
  Title
Translocations of the RARalpha gene in acute promyelocytic leukemia.
  Journal
Oncogene 20:7186-203 (2001)
DOI:10.1038/sj.onc.1204766

DBGET integrated database retrieval system