KEGG ORTHOLOGY: K08579

ORTHOLOGY: K08579

Entry

K08579                      KO

Symbol

CAPN10

Name

calpain-10 [EC:3.4.22.-]

Disease

H00409

Type 2 diabetes mellitus

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K08579  CAPN10; calpain-10
Peptidases and inhibitors [BR:ko01002]
Cysteine peptidases
  Family C2: calpain family
   K08579  CAPN10; calpain-10

Other DBs

GO:

0004198

Genes

HSA:	11132(CAPN10)

PTR:	460069(CAPN10)

PPS:	100994712(CAPN10)

GGO:	101149570(CAPN10)

PON:	100448147(CAPN10)

NLE:	100603845(CAPN10)

HMH:	116814391(CAPN10)

MCC:	716360(CAPN10)

MCF:	101866540(CAPN10)

MTHB:

126932552

MNI:	105473785(CAPN10)

CSAB:

103218216(CAPN10)

CATY:

105577551(CAPN10)

PANU:

101010286(CAPN10)

TGE:	112636611(CAPN10)

MLEU:

105531580(CAPN10)

RRO:	104658964(CAPN10)

RBB:	108521090(CAPN10)

TFN:	117094296(CAPN10)

PTEH:

111553775(CAPN10)

CANG:

105502946(CAPN10)

CJC:	100389664(CAPN10)

SBQ:	101030665(CAPN10)

CIMI:

108290789(CAPN10)

CSYR:

103256353(CAPN10)

MMUR:

105866424(CAPN10)

LCAT:

123643956(CAPN10)

PCOQ:

105824832(CAPN10)

OGA:	100954440(CAPN10)

MMU:	23830(Capn10)

MCAL:

110291411(Capn10)

MPAH:

110321610(Capn10)

RNO:	63834(Capn10)

MCOC:

116088788(Capn10)

ANU:	117722542(Capn10)

MUN:	110545737(Capn10)

CGE:	100752300(Capn10)

MAUA:

101837882(Capn10)

PROB:

127226702(Capn10)

PLEU:

114707804(Capn10)

MORG:

121433437 121447082

MFOT:

126490812

AAMP:

119821453(Capn10)

NGI:	103730836(Capn10)

HGL:	101703723(Capn10)

CPOC:

100725945(Capn10)

CCAN:

109693587(Capn10)

DORD:

105998834(Capn10)

DSP:	122115658(Capn10)

PLOP:

125350129(Capn10)

NCAR:

124980218

MMMA:

107138860(Capn10)

OCU:

100338885

OPI:

101518906

TUP:	102503095(CAPN10)

GVR:	103599572(CAPN10)

CFA:	607311(CAPN10)

CLUD:

112670021(CAPN10)

VVP:	112911227(CAPN10)

VLG:	121497118(CAPN10)

NPO:	129493789(CAPN10)

AML:	100478594(CAPN10)

UMR:	103662817(CAPN10)

UAH:	113249676(CAPN10)

UAR:	123791246(CAPN10)

ELK:

111141886

LLV:

125095316

MPUF:

101671374(CAPN10)

MNP:	132013707(CAPN10)

MLK:	131827262(CAPN10)

NVS:	122902470(CAPN10)

ORO:	101386430(CAPN10)

EJU:	114210763(CAPN10)

ZCA:	113920272(CAPN10)

MLX:	118011874(CAPN10)

NSU:	110570914(CAPN10)

LWW:	102742236(CAPN10)

FCA:	101089955(CAPN10)

PYU:	121014336(CAPN10)

PCOO:

112848617(CAPN10)

PBG:	122481992(CAPN10)

PVIV:

125158912(CAPN10)

LRUF:

124515030

PTG:	102961311(CAPN10)

PPAD:

109264801(CAPN10)

PUC:

125910996

AJU:

106984582

HHV:	120229536(CAPN10)

BTA:	789674(CAPN10)

BOM:	102271924(CAPN10)

BIU:	109556590(CAPN10)

BBUB:

102390183(CAPN10)

BBIS:

104987506(CAPN10)

CHX:	102186364(CAPN10)

OAS:	101104198(CAPN10)

BTAX:

128044560(CAPN10)

ODA:	120856662(CAPN10)

CCAD:

122437324(CAPN10)

MBEZ:

129541716(CAPN10)

SSC:	724069(CAPN10)

CFR:	102519912(CAPN10)

CBAI:

105063535(CAPN10)

CDK:	105106508(CAPN10)

VPC:	102531887(CAPN10)

BACU:

103009723(CAPN10)

BMUS:

118898434(CAPN10)

LVE:	103081017(CAPN10)

OOR:	101289281(CAPN10)

DLE:	111172000(CAPN10)

PCAD:

102986741(CAPN10)

PSIU:

116756407(CAPN10)

NASI:

112410804(CAPN10)

ECB:	111773881(CAPN10)

EPZ:	103560432(CAPN10)

EAI:	106832211(CAPN10)

MYD:	102760530(CAPN10)

MMYO:

118661379(CAPN10)

MLF:

102442724

PKL:	118709221(CAPN10)

EFUS:

103283245(CAPN10)

MNA:	107530008(CAPN10)

DRO:	112308020(CAPN10)

SHON:

119003039(CAPN10)

AJM:	119061030(CAPN10)

PDIC:

114494426(CAPN10)

PHAS:

123823161(CAPN10)

MMF:	118625412(CAPN10)

PPAM:

129068252(CAPN10)

HAI:	109374094(CAPN10)

RFQ:	117025665(CAPN10)

PALE:

102897266(CAPN10)

PGIG:

120601181(CAPN10)

PVP:	105302958(CAPN10)

RAY:	107510578(CAPN10)

MJV:	108383836(CAPN10)

TOD:	119256349(CAPN10)

SARA:

101553648(CAPN10)

SETR:

126008917(CAPN10)

LAV:	100656252(CAPN10)

TMU:

101349232

ETF:	101642856(CAPN10)

DNM:	101419585(CAPN10)

MDO:	100022544(CAPN10)

GAS:	123246873(CAPN10)

SHR:	100929245(CAPN10)

AFZ:

127563351

PCW:	110221276(CAPN10)

OAA:	100084727(CAPN10)

GGA:	424945(CAPN10)

PCOC:

116235388(CAPN10)

MGP:	100542080(CAPN10)

CJO:	107318140(CAPN10)

TPAI:

128082790(CAPN10)

LMUT:

125697313(CAPN10)

NMEL:

110398378(CAPN10)

APLA:

101798897(CAPN10)

ACYG:

106049397(CAPN10)

CATA:

118247128(CAPN10)

AFUL:

116492658(CAPN10)

TGU:	100227856(CAPN10)

LSR:	110477956(CAPN10)

SCAN:

103815345(CAPN10)

PMOA:

120504373(CAPN10)

OTC:	121336552(CAPN10)

PRUF:

121353855(CAPN10)

GFR:	102044179(CAPN10)

FAB:	101818657(CAPN10)

OMA:	130256878(CAPN10)

PHI:	102106055(CAPN10)

PMAJ:

107208708(CAPN10)

CCAE:

111933399(CAPN10)

CCW:	104687972(CAPN10)

CBRC:

103625131(CAPN10)

ETL:	114060776(CAPN10)

ZAB:	102067067(CAPN10)

ACHL:

103800139(CAPN10)

SVG:	106850354(CAPN10)

MMEA:

130574132(CAPN10)

HRT:	120757107(CAPN10)

FPG:	101921569(CAPN10)

FCH:	102058252(CAPN10)

CLV:	102091563(CAPN10)

EGZ:	104122282(CAPN10)

NNI:	104015636(CAPN10)

PCRI:

104032952(CAPN10)

PLET:

104623718(CAPN10)

EHS:	104503552(CAPN10)

PCAO:

104052853(CAPN10)

ACUN:

113483316(CAPN10)

TALA:

104359279(CAPN10)

PADL:

103922961(CAPN10)

AFOR:

103901496(CAPN10)

ACHC:

115346832(CAPN10)

HALD:

104320884(CAPN10)

HLE:	104835149(CAPN10)

AGEN:

126039503

GCL:

127019965

CCRI:

104163054(CAPN10)

CSTI:

104555100(CAPN10)

CMAC:

104481880(CAPN10)

MUI:	104547946(CAPN10)

BREG:

104636124(CAPN10)

FGA:	104082244(CAPN10)

GSTE:

104251117(CAPN10)

LDI:	104352525(CAPN10)

MNB:	103772091(CAPN10)

OHA:	104326449(CAPN10)

NNT:	104410056(CAPN10)

SHAB:

115612325(CAPN10)

DPUB:

104302964(CAPN10)

PGUU:

104463959(CAPN10)

ACAR:

104522247(CAPN10)

CPEA:

104390473(CAPN10)

AVIT:

104278772(CAPN10)

CVF:	104284944(CAPN10)

RTD:	128911551(CAPN10)

CUCA:

104057862(CAPN10)

TEO:	104382454(CAPN10)

BRHI:

104493946(CAPN10)

AAM:	106483806(CAPN10)

AROW:

112968517(CAPN10)

NPD:	112952534(CAPN10)

TGT:

104578245

DNE:	112980141(CAPN10)

SCAM:

104148838(CAPN10)

ASN:	102377394(CAPN10)

AMJ:	102557775(CAPN10)

CPOO:

109308509(CAPN10)

GGN:	109288061(CAPN10)

PSS:	102454199(CAPN10)

CMY:	102935486(CAPN10)

CCAY:

125643142(CAPN10)

DCC:	119861620(CAPN10)

CPIC:

101946163(CAPN10)

TST:	117882417(CAPN10)

CABI:

116838595(CAPN10)

MRV:	120371912(CAPN10)

ACS:	100566503(capn10)

ASAO:

132770415(CAPN10)

PVT:	110088870(CAPN10)

SUND:

121926005(CAPN10)

PBI:	103059044(CAPN10)

PMUR:

107302583(CAPN10)

CTIG:

120309703(CAPN10)

TSR:	106550447(CAPN10)

PGUT:

117659648(CAPN10)

APRI:

131201157(CAPN10)

PTEX:

113450526(CAPN10)

NSS:	113426224(CAPN10)

VKO:	123019450(CAPN10)

PMUA:

114598095(CAPN10)

PRAF:

128414877(CAPN10)

ZVI:	118093856(CAPN10)

HCG:	128350777(CAPN10)

GJA:	107120832(CAPN10)

STOW:

125438532(CAPN10)

EMC:	129332852(CAPN10)

XTR:	100379827(capn10)

NPR:	108804670(CAPN10)

MUO:	115478643(CAPN10)

GSH:	117367080(CAPN10)

DRE:	570311(capn10)

SRX:

107730431

SANH:

107692880(capn10)

SGH:

CCAR:

CAUA:

CGIB:

PTET:

122327887(capn10)

LROH:

127177130(capn10)

OMC:	131525749(capn10)

PPRM:

120495303(capn10)

RKG:	130092422(capn10)

MAMB:

125250708(capn10) 125251187

CIDE:

127498265

MASI:

127440270

TROS:

130555032(capn10)

TDW:	130418494(capn10)

MANU:

129443042(capn10)

IPU:

108261063

IFU:	128623831(capn10)

PHYP:

113533295(capn10)

SMEO:

124402725(capn10)

TFD:	113640656(capn10)

TVC:	132847052(capn10)

AMEX:

103034656(capn10)

CMAO:

118796841(capn10)

EEE:	113591600(capn10)

CHAR:

105906978(capn10)

TRU:	101071622(capn10)

TFS:	130538734(capn10)

TNG:	GSTEN00028467G001

LCO:	104935098(capn10)

NCC:	104957791(capn10)

TBEN:

117488587(capn10)

CGOB:

115022472(capn10)

PGEO:

117462680(capn10)

GACU:

117532579(capn10)

EMAC:

134865533(capn10)

ELY:	117271429(capn10)

EFO:	125902517(capn10)

PLEP:

121951361(capn10)

SLUC:

116037383(capn10)

ECRA:

117954292(capn10)

ESP:	116699094(capn10)

PFLV:

114565789(capn10)

GAT:	120815905(capn10)

PPUG:

119209358(capn10)

AFB:	129114301(capn10)

CLUM:

117746274(capn10)

PSWI:

130197902(capn10)

MSAM:

119884428 119902877(capn10)

SCHU:

122886511(capn10)

CUD:	121519645(capn10)

ALAT:

119011351(capn10)

MZE:	101477048(capn10)

ONL:	100700427(capn10)

OAU:	116323415(capn10)

OLA:	101155465(capn10)

OML:	112147301(capn10)

CSAI:

133452657(capn10)

XMA:	102228856(capn10)

XCO:	114146017(capn10)

XHE:	116721487(capn10)

PRET:

103479417(capn10)

PFOR:

103148935(capn10)

PLAI:

106953682(capn10)

PMEI:

106916467(capn10)

GAF:	122841378(capn10)

PPRL:

129362121(capn10)

CVG:	107092292(capn10)

CTUL:

119772944(capn10)

GMU:	124869870(capn10)

NFU:	107384065(capn10)

KMR:	108239413(capn10)

ALIM:

106537170(capn10)

NWH:	119414591(capn10)

AOCE:

111567648(capn10)

MCEP:

125010328(capn10)

POV:	109643313(capn10)

SSEN:

122770807(capn10)

HHIP:

117778063(capn10)

HSP:	118118288(capn10)

SMAU:

118310946(capn10)

LCF:

108883551

SDU:	111228948(capn10)

SLAL:

111654806(capn10)

XGL:	120798949(capn10)

HCQ:	109507412(capn10)

SSCV:

125984938

SBIA:

133511284(capn10)

PEE:	133411965(capn10)

PTAO:

133488679(capn10)

BPEC:

110158526(capn10)

MALB:

109969305(capn10)

BSPL:

114844323(capn10)

SJO:	128369301(capn10)

SASA:

106600574(capn10)

STRU:

115169354(capn10)

OTW:	112226535(capn10)

OMY:	110508357(capn10)

OGO:	124017363(capn10)

ONE:	115102858(capn10)

OKI:	109865625(capn10)

OKE:	118394908(capn10)

SALP:

111958121(capn10)

SNH:	120020306(capn10)

CCLU:

121581227(capn10)

ELS:	105020986(capn10)

SFM:

108935238

PKI:	111847368(capn10)

AANG:

118230852(capn10)

LOC:	102684952(capn10)

PSPA:

121323581 121326465(capn10)

ARUT:

117416829(capn10)

PSEX:

120536965(capn10)

LCM:	102352947(CAPN10)

CMK:	103184964(capn10)

RTP:

109930080

CPLA:

122556017(capn10)

HOC:	132821848(capn10)

LERI:

129703212(capn10)

PMRN:

BFO:

OED:

Reference

PMID:11017071

Authors

Horikawa Y, Oda N, Cox NJ, Li X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PE, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL, Bell GI

Title

Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.

Journal

Nat Genet 26:163-75 (2000)
DOI:10.1038/79876

Sequence

[hsa:11132]

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Disease (1)   
   KEGG DISEASE (1)   
Gene (680)   
   KEGG GENES (388)   
   KEGG MGENES (151)   
   RefGene (138)   
   OC (3)   
Literature (1)   
   PubMed (1)   
All databases (685)   

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