KEGG   ORTHOLOGY: K08774Help
Entry
K08774                      KO                                     

Name
TGFA
Definition
transforming growth factor, alpha
Pathway
EGFR tyrosine kinase inhibitor resistance
ErbB signaling pathway
Ras signaling pathway
PI3K-Akt signaling pathway
Pathways in cancer
Renal cell carcinoma
Pancreatic cancer
Glioma
Prostate cancer
Non-small cell lung cancer
Hepatocellular carcinoma
Disease
H00018  
Gastric cancer
H00048  
Hepatocellular carcinoma
H00516  
Isolated orofacial clefts
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04010 MAPK signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04012 ErbB signaling pathway
    K08774  TGFA; transforming growth factor, alpha
   04151 PI3K-Akt signaling pathway
    K08774  TGFA; transforming growth factor, alpha
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K08774  TGFA; transforming growth factor, alpha
   05212 Pancreatic cancer
    K08774  TGFA; transforming growth factor, alpha
   05225 Hepatocellular carcinoma
    K08774  TGFA; transforming growth factor, alpha
   05214 Glioma
    K08774  TGFA; transforming growth factor, alpha
   05211 Renal cell carcinoma
    K08774  TGFA; transforming growth factor, alpha
   05215 Prostate cancer
    K08774  TGFA; transforming growth factor, alpha
   05223 Non-small cell lung cancer
    K08774  TGFA; transforming growth factor, alpha
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K08774  TGFA; transforming growth factor, alpha
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
7039(TGFA)
PTR: 
737080(TGFA)
PPS: 
100973153(TGFA)
GGO: 
101140326(TGFA)
PON: 
100172994(TGFA)
NLE: 
100607585(TGFA)
MCC: 
613031(TGFA)
MCF: 
102145541(TGFA)
CSAB: 
103220091(TGFA)
RRO: 
104661322(TGFA)
RBB: 
108524582(TGFA)
CJC: 
100402888(TGFA)
SBQ: 
101045311(TGFA)
MMU: 
21802(Tgfa)
RNO: 
24827(Tgfa)
CGE: 
100754730(Tgfa)
NGI: 
103725901(Tgfa)
HGL: 
101723712(Tgfa)
CCAN: 
109701504(Tgfa)
OCU: 
100009482(TGFA)
TUP: 
102497817(TGFA)
CFA: 
403431(TGFA)
AML: 
100467724(TGFA)
UMR: 
103671814(TGFA)
FCA: 
101094921(TGFA)
PTG: 
102956554(TGFA)
AJU: 
106967765(TGFA)
BTA: 
540388(TGFA)
BOM: 
102264981(TGFA)
BIU: 
109565956(TGFA)
PHD: 
102339351(TGFA)
CHX: 
102185926(TGFA)
OAS: 
101106508(TGFA)
SSC: 
397484(TGFA)
CFR: 
102506694(TGFA)
CDK: 
105088937(TGFA)
BACU: 
103010563(TGFA)
LVE: 
103076982(TGFA)
ECB: 
100060423(TGFA)
EPZ: 
103547583(TGFA)
EAI: 
106828311(TGFA)
MYB: 
102262078(TGFA)
MYD: 
102768972(TGFA)
HAI: 
109385384(TGFA)
RSS: 
109438669(TGFA)
PALE: 
102887662(TGFA)
LAV: 
100665332(TGFA)
MDO: 
100032790(TGFA)
SHR: 
100928770(TGFA)
OAA: 
GGA: 
414743(TGFA)
MGP: 
100542303(TGFA)
CJO: 
107323712(TGFA)
APLA: 
101792073(TGFA)
ACYG: 
106046246(TGFA)
TGU: 
100222335(TGFA)
GFR: 
PHI: 
102109017(TGFA)
FPG: 
101917220(SNRPG)
FCH: 
102057058(TGFA)
CLV: 
102097060(TGFA)
AAM: 
106490250(TGFA)
ASN: 
102379226(TGFA)
AMJ: 
102570675(TGFA)
PSS: 
102445585(TGFA)
CMY: 
102947389(TGFA)
CPIC: 
101939693(TGFA)
PVT: 
110072211(TGFA)
PBI: 
103053928(TGFA)
GJA: 
107118762(TGFA)
XLA: 
108696277(LOC733728.L) 108712769(tgfa.S) 496037(tgfa.L)
XTR: 
NPR: 
DRE: 
100034402(tgfa)
SRX: 
SANH: 
SGH: 
107568177(tgfa)
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
104955540(tgfa)
MZE: 
101486967(tgfa)
OLA: 
XMA: 
102232831(tgfa)
CSEM: 
LCF: 
HCQ: 
109531425(tgfa)
BPEC: 
SASA: 
ELS: 
SFM: 
108920173(tgfa)
LCM: 
102367184(TGFA)
CMK: 
BFO: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:6088071
  Authors
Derynck R, Roberts AB, Winkler ME, Chen EY, Goeddel DV
  Title
Human transforming growth factor-alpha: precursor structure and expression in E. coli.
  Journal
Cell 38:287-97 (1984)
DOI:10.1016/0092-8674(84)90550-6
  Sequence
[hsa:7039]

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