KEGG   ORTHOLOGY: K08798Help
Entry
K08798                      KO                                     

Name
MARK
Definition
MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Brite
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K08798  MARK; MAP/microtubule affinity-regulating kinase
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: CAMK group
  CAMKL family
   K08798  MARK; MAP/microtubule affinity-regulating kinase
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     K08798  MARK; MAP/microtubule affinity-regulating kinase
BRITE hierarchy
Genes
HSA: 
2011(MARK2) 4139(MARK1) 4140(MARK3) 57787(MARK4)
PTR: 
453184(MARK3) 456123(MARK4) 469683(MARK1) 741494(MARK2)
PPS: 
100977729(MARK3) 100980135(MARK2) 100989285(MARK1) 100992653(MARK4)
GGO: 
101127838(MARK3) 101133345(MARK1) 101136507(MARK4) 101142194(MARK2)
PON: 
100431691(MARK3) 100433440(MARK2) 100454879(MARK4) 100456064(MARK1)
NLE: 
100579541(MARK3) 100581822(MARK1) 100594774(MARK4) 100595666(MARK2)
MCC: 
695234(MARK3) 710695(MARK1) 715346(MARK4) 718065(MARK2)
MCF: 
101925189(MARK3) 102134233(MARK1) 102143161(MARK2) 102145145(MARK4)
RRO: 
104654423(MARK3) 104666094(MARK1) 104672880(MARK2) 104673449(MARK4)
CJC: 
MMU: 
13728(Mark2) 17169(Mark3) 226778(Mark1) 232944(Mark4)
RNO: 
117016(Mark1) 170577(Mark3) 60328(Mark2) 680407(Mark4)
CGE: 
NGI: 
HGL: 
101707850(Mark2) 101711152(Mark1) 101713017(Mark3) 101719511 101726420(Mark4)
OCU: 
TUP: 
CFA: 
478965(MARK1) 483769(MARK2) 484449(MARK4) 611285(MARK3)
AML: 
100467224(MARK2) 100474641(MARK1) 100481440(MARK4) 100482675(MARK3)
UMR: 
103657182(MARK4) 103658278(MARK1) 103676892(MARK3) 103679415(MARK2)
FCA: 
PTG: 
102949758(MARK3) 102954510(MARK1) 102960665(MARK2) 102971274(MARK4)
BTA: 
525675(MARK4) 534872(MARK3) 535197(MARK2) 539563(MARK1)
BOM: 
102271460(MARK3) 102274607(MARK1) 102280394(MARK2) 102287824(MARK4)
PHD: 
102318162(MARK4) 102320726(MARK1) 102324872(MARK2) 102326255(MARK3) 102328303
CHX: 
OAS: 
101105030(MARK3) 101105515(MARK1) 101115819(MARK4) 101121302(MARK2) 106991822
SSC: 
100624209(MARK4) 100624523(MARK1) 100625932 100737238(MARK2)
CFR: 
102503683(MARK1) 102504704(MARK4) 102513459(MARK3) 102520242(MARK2)
BACU: 
LVE: 
103075860(MARK1) 103076919(MARK4) 103082212(MARK3) 103088748(MARK2)
ECB: 
100049882(MARK2) 100054005(MARK1) 100059464(MARK3) 100070770(MARK4)
MYB: 
MYD: 
102752116(MARK2) 102757894(MARK4) 102765288 102769219(MARK3) 102772379(MARK1)
PALE: 
102882803(MARK2) 102886835(MARK1) 102887051(MARK3) 102887913(MARK4)
MDO: 
100014334(MARK2) 100021111(MARK3) 100024528(MARK1) 100031216(MARK4)
SHR: 
100914670(MARK2) 100917510(MARK1) 100923427(MARK4) 100925650(MARK3)
OAA: 
100076749(MARK3) 100080890(MARK1)
GGA: 
421342(MARK1) 423480(MARK3)
MGP: 
100544800(MARK1) 100550645(MARK3)
APLA: 
TGU: 
100219055(MARK3) 100224882(MARK1)
GFR: 
FAB: 
101805653(MARK1) 101805833(MARK2) 101807077(MARK3)
PHI: 
102103467(MARK2) 102103520(MARK4) 102108680(MARK3) 102113253(MARK1)
CCW: 
FPG: 
101917002(MARK1) 101919390(MARK3) 101920950(MARK4)
FCH: 
102047447(MARK1) 102058488(MARK3) 106631056(MARK4)
CLV: 
ASN: 
102371105(MARK3) 102375333(MARK2) 102379467(MARK4) 102380403(MARK1)
AMJ: 
102558221(MARK3) 102569198(MARK1) 102572476(MARK4) 102576315(MARK2)
PSS: 
102454865(MARK1) 102456409(MARK3) 102458022 102461077(MARK2)
CMY: 
102930948(MARK1) 102936538(MARK2) 102942529(MARK3) 102944699(MARK4)
ACS: 
100553482(mark4) 100556651(mark3) 100559635(mark1) 100566972(mark2) 103282645
PBI: 
103055239 103059538(MARK2) 103062879(MARK1) 103067320(MARK4) 103068272(MARK3)
XLA: 
380117(mark2) 399395(mark3) 432201(mark1) 495312
XTR: 
100329119(mark3) 100490022(mark1) 100491038(mark4) 594939(mark2)
DRE: 
100003170(mark1) 100005996(mark2b) 334300(mark3a) 562231(mark2a) 571279 767634(mark3b)
TRU: 
101061627(mark3) 101067343 101071085(mark2) 101074476(mark1) 101076656(mark4)
MZE: 
OLA: 
XMA: 
LCM: 
102345624(MARK2) 102353519(MARK4) 102355219(MARK1) 102365343(MARK3)
CMK: 
BFO: 
CIN: 
100184744(mark2)
SPU: 
592325(MARK3)
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
Dyak_GE12057(dyak_GLEANR_12341) Dyak_GE24627(dyak_GLEANR_8305) Dyak_GE24628(dyak_GLEANR_8306)
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
410717(par-1)
SOC: 
AEC: 
HST: 
CFO: 
NVI: 
TCA: 
656926(par-1) 661848
BMOR: 
PXY: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG04756(Cbr-par-1)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
SMM: 
NVE: 
HMG: 
100214508(mark3)
TAD: 
AQU: 
VCN: 
ADL: 
CPUT: 
MBR: 
SRE: 
DDI: 
DPP: 
DFA: 
DFA_05190(mrkB) DFA_06667(mrkA) DFA_07946(mrkC)
EIV: 
ACAN: 
TET: 
PTM: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Dequiedt F, Martin M, Von Blume J, Vertommen D, Lecomte E, Mari N, Heinen MF, Bachmann M, Twizere JC, Huang MC, Rider MH, Piwnica-Worms H, Seufferlein T, Kettmann R
  Title
New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.
  Journal
Mol Cell Biol 26:7086-102 (2006)
  Sequence
[hsa:4140 2011]
Reference
  Authors
Biernat J, Wu YZ, Timm T, Zheng-Fischhofer Q, Mandelkow E, Meijer L, Mandelkow EM
  Title
Protein kinase MARK/PAR-1 is required for neurite outgrowth and establishment of  neuronal polarity.
  Journal
Mol Biol Cell 13:4013-28 (2002)
  Sequence
[hsa:2011]

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