KEGG   ORTHOLOGY: K09188Help
Entry
K09188                      KO                                     
Name
MLL3
Definition
histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]
Pathway
Lysine degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K09188  MLL3; histone-lysine N-methyltransferase MLL3
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 Trithorax
    K09188  MLL3; histone-lysine N-methyltransferase MLL3
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
   HMT complexes
    MLL3/MLL4 complex
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
BRITE hierarchy
Other DBs
Genes
HSA: 
58508(MLL3)
PTR: 
463875(MLL3)
PPS: 
100992231(MLL3)
GGO: 
101134599(MLL3)
PON: 
100451228(MLL3)
MCC: 
716753(MLL3)
MMU: 
231051(Mll3)
RNO: 
CFA: 
611094(MLL3)
AML: 
FCA: 
101084095(MLL3)
SSC: 
100514805(MLL3)
ECB: 
100064812
MDO: 
100019161
SHR: 
100920575(MLL3)
OAA: 
100074286
GGA: 
420437(MLL3)
TGU: 
100227193(MLL3)
ACS: 
100556055
XTR: 
100486829(mll3)
DRE: 
560793(mll3a)
OLA: 
101162786
BFO: 
BRAFLDRAFT_125138
SPU: 
591084
DME: 
Dmel_CG3848(trr)
DPO: 
Dpse_GA17728
DAN: 
Dana_GF19475
DER: 
Dere_GG12672
DPE: 
Dper_GL18348
DSE: 
Dsec_GM18944
DSI: 
Dsim_GD16408
DWI: 
Dwil_GK16377
DYA: 
Dyak_GE16999
DGR: 
Dgri_GH17848
DMO: 
Dmoj_GI21761
DVI: 
Dvir_GJ19139
AGA: 
AgaP_AGAP011192
AAG: 
AaeL_AAEL005380
CQU: 
CpipJ_CPIJ011192
AME: 
411466
NVI: 
100120205(Trr)
API: 
100159693 100571907
PHU: 
Phum_PHUM411800
ISC: 
IscW_ISCW023206
CEL: 
CELE_T12D8.1(set-16)
CBR: 
CBG18244(Cbr-set-16)
BMY: 
Bm1_21795
TSP: 
Tsp_02214
NVE: 
NEMVE_v1g116282
HMG: 
100209023
CME: 
CMD005C
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruault M, Brun ME, Ventura M, Roizes G, De Sario A
  Title
MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia.
  Journal
Gene 284:73-81 (2002)
Reference
  Authors
Ansari KI, Mandal SS
  Title
Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
  Journal
FEBS J 277:1790-804 (2010)
Reference
  Authors
Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K
  Title
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
  Journal
J Biol Chem 282:20395-406 (2007)
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