KEGG   ORTHOLOGY: K09188Help
Entry
K09188                      KO                                     

Name
MLL3
Definition
histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43]
Pathway
Lysine degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K09188  MLL3; histone-lysine N-methyltransferase MLL3
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys4 Trithorax
    K09188  MLL3; histone-lysine N-methyltransferase MLL3
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
   HMT complexes
    MLL3/MLL4 complex
     K09188  MLL3; histone-lysine N-methyltransferase MLL3
BRITE hierarchy
Other DBs
Genes
HSA: 
58508(KMT2C)
PTR: 
463875(KMT2C)
PPS: 
100992231(KMT2C)
GGO: 
101134599(MLL3)
PON: 
100451228(MLL3)
NLE: 
100607151(MLL3)
MCC: 
716753(MLL3)
MCF: 
102128002(KMT2C)
CJC: 
100401397(KMT2C)
MMU: 
231051(Kmt2c)
RNO: 
502710(Kmt2c)
CGE: 
100767367(Kmt2c)
NGI: 
103745326(Kmt2c)
HGL: 
101698170(Kmt2c)
OCU: 
100353688(KMT2C)
TUP: 
102479012(KMT2C)
CFA: 
611094(MLL3)
AML: 
UMR: 
103660985(KMT2C)
FCA: 
101084095(KMT2C)
PTG: 
102964154(KMT2C)
BTA: 
789336(KMT2C)
BOM: 
102267186(KMT2C)
PHD: 
102317507(KMT2C)
CHX: 
OAS: 
101115617(MLL3)
SSC: 
100514805(KMT2C)
CFR: 
102507730(KMT2C)
BACU: 
103004433(KMT2C)
LVE: 
103078348(KMT2C)
ECB: 
100064812(KMT2C)
MYB: 
102246704(KMT2C)
MYD: 
102759674(KMT2C)
PALE: 
102897550(KMT2C)
MDO: 
100019161(KMT2C)
SHR: 
100920575(MLL3)
OAA: 
100074286(KMT2C)
GGA: 
420437(MLL3)
APLA: 
101796266(KMT2C)
TGU: 
100227193(MLL3)
FAB: 
101806346(KMT2C)
PHI: 
102099277(KMT2C)
FPG: 
101917176(KMT2C)
FCH: 
102047191(KMT2C)
CLV: 
102097963(KMT2C)
ASN: 
102379342(KMT2C)
AMJ: 
102567474(KMT2C)
PSS: 
102459016(KMT2C)
CMY: 
102948345(KMT2C)
ACS: 
100556055(kmt2c)
PBI: 
103049419(KMT2C)
XTR: 
100486829(kmt2c)
DRE: 
560793(kmt2ca)
MZE: 
OLA: 
XMA: 
LCM: 
102347272(KMT2C)
CMK: 
BFO: 
CIN: 
778537(alr-like)
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
102654133 411466(GB12881)
NVI: 
TCA: 
API: 
PHU: 
ISC: 
CEL: 
CELE_T12D8.1(set-16)
CBR: 
CBG18244(Cbr-set-16)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
NVE: 
HMG: 
CME: 
GSL: 
CCP: 
DFA: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ruault M, Brun ME, Ventura M, Roizes G, De Sario A
  Title
MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia.
  Journal
Gene 284:73-81 (2002)
  Sequence
[hsa:58508]
Reference
  Authors
Ansari KI, Mandal SS
  Title
Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing.
  Journal
FEBS J 277:1790-804 (2010)
Reference
  Authors
Cho YW, Hong T, Hong S, Guo H, Yu H, Kim D, Guszczynski T, Dressler GR, Copeland TD, Kalkum M, Ge K
  Title
PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
  Journal
J Biol Chem 282:20395-406 (2007)
  Sequence
[hsa:58508]

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