KEGG   ORTHOLOGY: K09234Help
Entry
K09234                      KO                                     

Name
WT1
Definition
Wilms tumor protein 1
Pathway
Transcriptional misregulation in cancer
Disease
H00607  
46,XY disorders of sex development (Disorders of gonadal development)
H00626  
Nephrotic syndrome and focal segmental glomerulosclerosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K09234  WT1; Wilms tumor protein 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Zinc finger
   Cys2His2 developmental/cell cycle regulators, GLI-like
    K09234  WT1; Wilms tumor protein 1
BRITE hierarchy
Genes
HSA: 
7490(WT1)
PTR: 
737987(WT1)
PPS: 
GGO: 
PON: 
NLE: 
MCC: 
696061(WT1)
MCF: 
RRO: 
CJC: 
MMU: 
22431(Wt1)
RNO: 
24883(Wt1)
CGE: 
NGI: 
HGL: 
OCU: 
TUP: 
CFA: 
609253(WT1)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
782183(WT1)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
397338(WT1)
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
MGP: 
APLA: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
378664(wt1-b)
XTR: 
DRE: 
30245(wt1a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Weiss TC, Romaniuk PJ
  Title
Contribution of individual amino acids to the RNA binding activity of the Wilms'  tumor suppressor protein WT1.
  Journal
Biochemistry 48:148-55 (2009)
  Sequence
[hsa:7490]
Reference
  Authors
Rivera MN, Kim WJ, Wells J, Stone A, Burger A, Coffman EJ, Zhang J, Haber DA
  Title
The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity.
  Journal
Proc Natl Acad Sci U S A 106:8338-43 (2009)
  Sequence
[hsa:7490]

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