KEGG   ORTHOLOGY: K09355Help
Entry
K09355                      KO                                     

Name
PBX1
Definition
pre-B-cell leukemia transcription factor 1
Pathway
ko04927  Cortisol synthesis and secretion
ko04934  Cushing's syndrome
ko05202  Transcriptional misregulation in cancer
Disease
H00001  B lymphoblastic leukemia/lymphoma
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Endocrine system
   04927 Cortisol synthesis and secretion
    K09355  PBX1; pre-B-cell leukemia transcription factor 1
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K09355  PBX1; pre-B-cell leukemia transcription factor 1
  Endocrine and metabolic diseases
   04934 Cushing's syndrome
    K09355  PBX1; pre-B-cell leukemia transcription factor 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  Helix-turn-helix
   Homeo domain only, PBC
    K09355  PBX1; pre-B-cell leukemia transcription factor 1
BRITE hierarchy
Genes
HSA: 5087(PBX1)
PTR: 457474(PBX1)
PPS: 100990886(PBX1)
GGO: 101150155(PBX1)
PON: 100440755(PBX1)
NLE: 100591595(PBX1)
MCC: 694416(PBX1)
MCF: 102132310(PBX1)
CSAB: 103230699(PBX1)
RRO: 104670173(PBX1)
RBB: 108538376(PBX1)
CJC: 100387577(PBX1)
SBQ: 101050091(PBX1)
MMU: 18514(Pbx1)
RNO: 304947(Pbx1)
CGE: 100772263(Pbx1)
NGI: 103746118(Pbx1)
HGL: 101714961(Pbx1)
OCU: 100341186(PBX1)
TUP: 102476678(PBX1)
CFA: 488669(PBX1)
AML: 100474783(PBX1)
UMR: 103658284(PBX1)
ORO: 101370420(PBX1)
FCA: 101081781(PBX1)
PTG: 102968400(PBX1)
AJU: 106965568(PBX1)
BTA: 540688(PBX1)
BOM: 102275855(PBX1)
BIU: 109577841(PBX1)
PHD: 102314879(PBX1)
CHX: 102170836(PBX1)
OAS: 101108880(PBX1)
SSC: 100154639(PBX1)
CFR: 102517981(PBX1)
CDK: 105092708(PBX1)
BACU: 103016479(PBX1)
LVE: 103082318(PBX1)
OOR: 101288266(PBX1)
ECB: 100058426(PBX1)
EPZ: 103547337(PBX1)
EAI: 106831135(PBX1)
MYB: 102241711(PBX1)
MYD: 102766693(PBX1)
HAI: 109392313(PBX1)
RSS: 109455651(PBX1)
PALE: 102898077(PBX1)
LAV: 100658312(PBX1)
TMU: 101356255
MDO: 100016502(PBX1)
SHR: 100928718(PBX1)
OAA: 100077375(PBX1)
GGA: 395505(PBX1)
MGP: 100548499(PBX1)
CJO: 107317263(PBX1)
APLA: 101793117(PBX1)
ACYG: 106041605
TGU: 100231384(PBX1)
GFR: 102033563(PBX1)
FAB: 101809800(PBX1)
PHI: 102114683(PBX1)
PMAJ: 107208314(PBX1)
CCW: 104695465(PBX1)
FPG: 101924009(PBX1)
FCH: 102049171(PBX1)
CLV: 102086514(PBX1)
EGZ: 104132099(PBX1)
AAM: 106491772 106493870(PBX1)
ASN: 102368257(PBX1)
AMJ: 106737223(PBX1)
PSS: 102458432(PBX1)
CMY: 102934185(PBX1)
CPIC: 101949430(PBX1)
ACS: 100567807(pbx1)
PVT: 110087589(PBX1) 110089777(PBX2)
PBI: 103057331(PBX1) 103057809
GJA: 107107275
XLA: 108714419 399184(pbx1.S)
XTR: 100216094(pbx1)
NPR: 108789127
DRE: 570960(pbx1b) 58138(pbx1a)
AMEX: 103036062(pbx4) 103038228
TRU: 101069707 101080114(pbx4)
PRET: 103463997(pbx1) 103468757(pbx4) 103479586
NFU: 107378327(pbx4) 107383950 107387365(pbx1)
LCM: 102366427(PBX1)
CIN: 778982(pbx)
APLC: 110988573
DME: Dmel_CG8933(exd)
DSI: Dsimw501_GD17261(Dsim_GD17261)
AGA: AgaP_AGAP004696(EXD_ANOGA)
AAG: 5576927
AME: 408763(exd)
BIM: 100746347
BTER: 100647014
SOC: 105204454
AEC: 105151999
ACEP: 105624699
HST: 105190126
CFO: 105251567
PGC: 109858107
TCA: 641540(Exd)
DPA: 109546235
BMOR: 692478(Exd)
PMAC: 106711852
PRAP: 110991808
PXY: 105398635
API: 100168368
DNX: 107170144
FCD: 110852798
TUT: 107361812
CEL: CELE_F17A2.5(ceh-40) CELE_F31E3.1(ceh-20)
CBR: CBG16494(Cbr-ceh-20)
BMY: Bm1_19405
TSP: Tsp_00508
OBI: 106874257
LAK: 106170036
SHX: MS3_09264
EPA: 110244790
ADF: 107337926
HMG: 100203767
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Laurent A, Bihan R, Omilli F, Deschamps S, Pellerin I
  Title
PBX proteins: much more than Hox cofactors.
  Journal
Int J Dev Biol 52:9-20 (2008)
DOI:10.1387/ijdb.072304al
Reference
  Authors
Thameem F, Wolford JK, Bogardus C, Prochazka M
  Title
Analysis of PBX1 as a candidate gene for type 2 diabetes mellitus in Pima Indians.
  Journal
Biochim Biophys Acta 1518:215-20 (2001)
  Sequence
[hsa:5087]

DBGET integrated database retrieval system