KEGG   ORTHOLOGY: K09593Help
Entry
K09593                      KO                                     

Name
GAB1
Definition
GRB2-associated-binding protein 1
Pathway
ko01521  EGFR tyrosine kinase inhibitor resistance
ko04012  ErbB signaling pathway
ko04014  Ras signaling pathway
ko04072  Phospholipase D signaling pathway
ko04722  Neurotrophin signaling pathway
ko05100  Bacterial invasion of epithelial cells
ko05205  Proteoglycans in cancer
ko05211  Renal cell carcinoma
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
   04012 ErbB signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
   04072 Phospholipase D signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
 Organismal Systems
  Nervous system
   04722 Neurotrophin signaling pathway
    K09593  GAB1; GRB2-associated-binding protein 1
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K09593  GAB1; GRB2-associated-binding protein 1
   05225 Hepatocellular carcinoma
    K09593  GAB1; GRB2-associated-binding protein 1
   05226 Gastric cancer
    K09593  GAB1; GRB2-associated-binding protein 1
   05211 Renal cell carcinoma
    K09593  GAB1; GRB2-associated-binding protein 1
  Infectious diseases
   05100 Bacterial invasion of epithelial cells
    K09593  GAB1; GRB2-associated-binding protein 1
  Drug resistance
   01521 EGFR tyrosine kinase inhibitor resistance
    K09593  GAB1; GRB2-associated-binding protein 1
BRITE hierarchy
Genes
HSA: 2549(GAB1)
PTR: 461516(GAB1)
PPS: 100990740(GAB1)
GGO: 101147447(GAB1)
PON: 100458884(GAB1)
NLE: 100600534(GAB1)
MCC: 700367(GAB1)
MCF: 101865745(GAB1)
CSAB: 103236312(GAB1)
RRO: 104657016(GAB1)
RBB: 108517109(GAB1)
CJC: 100406544(GAB1)
SBQ: 101040995(GAB1)
MMU: 14388(Gab1)
RNO: 361388(Gab1)
CGE: 100753832(Gab1)
NGI: 103742387(Gab1)
HGL: 101721604(Gab1)
CCAN: 109693395(Gab1)
OCU: 100346125(GAB1)
TUP: 102497468(GAB1)
CFA: 483808(GAB1)
AML: 100472197(GAB1)
UMR: 103658080(GAB1)
ORO: 101380995(GAB1)
FCA: 101088326(GAB1)
PTG: 102959239(GAB1)
AJU: 106983704(GAB1)
BTA: 540085(GAB1)
BOM: 102282859(GAB1)
BIU: 109571216(GAB1)
PHD: 102331357(GAB1)
CHX: 102179970(GAB1)
OAS: 101112165(GAB1)
SSC: 100511026(GAB1)
CFR: 102512457(GAB1)
CDK: 105092112(GAB1)
BACU: 102999413(GAB1)
LVE: 103085000(GAB1)
OOR: 101286927(GAB1)
ECB: 100062924(GAB1)
EPZ: 103558534(GAB1)
EAI: 106829157(GAB1)
MYB: 102245609(GAB1)
MYD: 102765653(GAB1)
HAI: 109393101(GAB1)
RSS: 109446921(GAB1)
PALE: 102881252(GAB1)
LAV: 100669213(GAB1)
TMU: 101355014
MDO: 100019200(GAB1)
SHR: 100925463(GAB1)
OAA: 100082582(GAB1)
GGA: 422456(GAB1)
MGP: 100543824(GAB1)
CJO: 107313159(GAB1)
APLA: 101793334(GAB1)
ACYG: 106046685(GAB1)
TGU: 100222864(GAB1)
GFR: 102039834(GAB1)
FAB: 101813104(GAB1)
PHI: 102108222(GAB1)
PMAJ: 107203076(GAB1)
CCW: 104697265(GAB1)
FPG: 101920388(GAB1)
FCH: 102060203(GAB1)
CLV: 102099002(GAB1)
EGZ: 104130578(GAB1)
AAM: 106492079(GAB1)
ASN: 102379491(GAB1)
AMJ: 102574158(GAB1)
PSS: 102458933(GAB1)
CMY: 102930818(GAB1)
CPIC: 101947163(GAB1)
ACS: 100553916(gab1)
PVT: 110073637(GAB1)
PBI: 103059660(GAB1)
GJA: 107120271(GAB1)
XLA: 734245(gab1.L) 734248(gab1.S)
XTR: 100485031(gab1)
NPR: 108784230(GAB1)
DRE: 406666(gab1)
SANH: 107655091(gab1) 107684448
SGH: 107550557(gab1) 107598765
IPU: 108263355(gab1)
AMEX: 103043031(gab1)
TRU: 101067799(gab1) 101078435
LCO: 104917899(gab1) 104932638
NCC: 104964863(gab1)
MZE: 101471751(gab1) 101473094
OLA: 101157091 101173122(gab1)
XMA: 102218636 102230629(gab1)
PRET: 103471132(gab1) 103480707
NFU: 107376790 107389466(gab1)
CSEM: 103383342(gab1)
HCQ: 109511334(gab1) 109511906
BPEC: 110156233(gab1)
ELS: 105007265 105020948(gab1)
SFM: 108924555(gab1) 108936670
LCM: 102356417(GAB1)
CMK: 103181326(gab1)
SPU: 100893661
APLC: 110984076
EPA: 110248936
ADF: 107342180
AQU: 105313571
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8596638
  Authors
Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ
  Title
A Grb2-associated docking protein in EGF- and insulin-receptor signalling.
  Journal
Nature 379:560-4 (1996)
DOI:10.1038/379560a0
  Sequence
[hsa:2549]
Reference
  Authors
Aasrum M, Odegard J, Sandnes D, Christoffersen T
  Title
The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.
  Journal
Biochim Biophys Acta 1833:3286-94 (2013)
DOI:10.1016/j.bbamcr.2013.10.004
  Sequence
[rno:361388]

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