KEGG   ORTHOLOGY: K10054Help
Entry
K10054                      KO                                     

Name
PML, TRIM19
Definition
probable transcription factor PML
Pathway
ko04120  Ubiquitin mediated proteolysis
ko04144  Endocytosis
ko05164  Influenza A
ko05168  Herpes simplex infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05221  Acute myeloid leukemia
Disease
H00003  Acute myeloid leukemia (AML)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10054  PML, TRIM19; probable transcription factor PML
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K10054  PML, TRIM19; probable transcription factor PML
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K10054  PML, TRIM19; probable transcription factor PML
   05202 Transcriptional misregulation in cancers
    K10054  PML, TRIM19; probable transcription factor PML
   05221 Acute myeloid leukemia
    K10054  PML, TRIM19; probable transcription factor PML
  Infectious diseases
   05164 Influenza A
    K10054  PML, TRIM19; probable transcription factor PML
   05168 Herpes simplex infection
    K10054  PML, TRIM19; probable transcription factor PML
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    K10054  PML, TRIM19; probable transcription factor PML
BRITE hierarchy
Genes
HSA: 5371(PML)
PTR: 453736(PML)
PPS: 100993007(PML)
GGO: 101145052(PML)
PON: 100445630(PML)
NLE: 100607016(PML)
MCC: 700379(PML)
MCF: 102135847(PML)
CSAB: 103245348(PML)
RRO: 104678056(PML)
RBB: 108524152(PML)
CJC: 100388843(PML)
SBQ: 101042469(PML) 101045516
MMU: 18854(Pml)
RNO: 315713(Pml)
CGE: 100757598(Pml)
NGI: 103736862(Pml)
HGL: 101707749(Pml)
CCAN: 109687659
OCU: 100351382(PML)
TUP: 102474405(PML)
CFA: 487641(PML)
AML: 100475070(PML)
UMR: 103679001(PML)
ORO: 101365827(PML)
FCA: 101086975(PML)
PTG: 102963011(PML)
AJU: 106979429(PML)
BTA: 100138545(PML)
BOM: 102283005 102286043(PML)
BIU: 109575524(PML)
PHD: 102319090(PML)
CHX: 102173973(PML)
OAS: 101111580(PML)
SSC: 100157336(PML)
CFR: 102504760(PML)
CDK: 105087276
BACU: 103013991(PML)
LVE: 103090340(PML)
OOR: 101283102(PML)
ECB: 100062744(PML)
EPZ: 103560966(PML)
MYB: 102242938(PML)
MYD: 102775373(PML)
HAI: 109396273(PML)
RSS: 109449602(PML)
PALE: 102895190(PML)
LAV: 100663907(PML)
TMU: 101356208
MDO: 100029464(PML)
SHR: 100925902(PML)
OAA: 100076474(PML)
GGA: 100857563(PMLL) 415302(PML)
MGP: 104912756(PML) 104912761
CJO: 107318588 107318590(PML)
APLA: 101796105(PML)
ACYG: 106044181(PML) 106044208
PHI: 102107893(PML)
PMAJ: 107209110(PML)
FPG: 101910511(PML) 101910853
FCH: 102050333(PML) 102050681
AAM: 106500165(PML) 106500166
CMY: 102944212(PML) 102947589
CPIC: 101946293(PML) 101948754
PVT: 110084440(PML)
PBI: 103048599 103057424(PML)
GJA: 107109157
CMK: 103190730
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Guo A, Salomoni P, Luo J, Shih A, Zhong S, Gu W, Pandolfi PP
  Title
The function of PML in p53-dependent apoptosis.
  Journal
Nat Cell Biol 2:730-6 (2000)
DOI:10.1038/35036365
  Sequence
[hsa:5371]
Reference
  Authors
Lin HK, Bergmann S, Pandolfi PP
  Title
Cytoplasmic PML function in TGF-beta signalling.
  Journal
Nature 431:205-11 (2004)
DOI:10.1038/nature02783
  Sequence
[hsa:5371] [mmu:18854]
Reference
  Authors
Dellaire G, Ching RW, Ahmed K, Jalali F, Tse KC, Bristow RG, Bazett-Jones DP
  Title
Promyelocytic leukemia nuclear bodies behave as DNA damage sensors whose response to DNA double-strand breaks is regulated by NBS1 and the kinases ATM, Chk2, and ATR.
  Journal
J Cell Biol 175:55-66 (2006)
DOI:10.1083/jcb.200604009
  Sequence
[hsa:5371]
Reference
  Authors
Cuchet D, Sykes A, Nicolas A, Orr A, Murray J, Sirma H, Heeren J, Bartelt A, Everett RD
  Title
PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication.
  Journal
J Cell Sci 124:280-91 (2011)
DOI:10.1242/jcs.075390
  Sequence
[hsa:5371]

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