KEGG   ORTHOLOGY: K10127Help
Entry
K10127                      KO                                     

Name
MDM4, MDMX
Definition
protein Mdm4
Pathway
p53 signaling pathway
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell growth and death
   04115 p53 signaling pathway
    K10127  MDM4, MDMX; protein Mdm4
 Human Diseases
  Cancers
   05206 MicroRNAs in cancer
    K10127  MDM4, MDMX; protein Mdm4
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  single Ring-finger type E3
   MDM2/MDM4 proteins
    K10127  MDM4, MDMX; protein Mdm4
BRITE hierarchy
Genes
HSA: 
4194(MDM4)
PTR: 
457658(MDM4)
PPS: 
100981338(MDM4)
GGO: 
101133824(MDM4)
PON: 
100461293(MDM4)
NLE: 
100594153(MDM4)
MCC: 
699563(MDM4)
MCF: 
102129859(MDM4)
CJC: 
100401846(MDM4)
MMU: 
17248(Mdm4)
RNO: 
304798(Mdm4)
CGE: 
100752007(Mdm4)
NGI: 
103731879(Mdm4)
HGL: 
101720853(Mdm4)
OCU: 
100351683(MDM4)
TUP: 
102494972(MDM4)
CFA: 
478939(MDM4)
AML: 
100466328(MDM4)
UMR: 
103670975(MDM4)
FCA: 
101082460(MDM4)
PTG: 
102966847(MDM4)
BTA: 
514225(MDM4)
BOM: 
102269169(MDM4)
PHD: 
102315112(MDM4)
CHX: 
102191635(MDM4)
OAS: 
101112914(MDM4)
SSC: 
100512731(MDM4)
CFR: 
102504662(MDM4)
BACU: 
103014402(MDM4)
LVE: 
103070439(MDM4)
ECB: 
100050113(MDM4)
MYB: 
102256687(MDM4)
MYD: 
102756790(MDM4)
PALE: 
102896990(MDM4)
MDO: 
100017700(MDM4)
SHR: 
100930617(MDM4)
OAA: 
100075524(MDM4)
GGA: 
419823(MDM4)
MGP: 
APLA: 
101795668(MDM4)
TGU: 
100232319(MDM4)
FAB: 
101810700(MDM4)
PHI: 
102101182(MDM4)
FPG: 
101915267(MDM4)
FCH: 
102047084(MDM4)
CLV: 
102092604(MDM4)
ASN: 
102386667(MDM4)
AMJ: 
102571670(MDM4)
PSS: 
102461975(MDM4)
CMY: 
102936372(MDM4)
ACS: 
100567197(mdm4)
PBI: 
103055295(MDM4)
XLA: 
398466(mdm4)
XTR: 
100216294(mdm4)
DRE: 
334932(mdm4)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102358918(MDM4)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Chen L, Gilkes DM, Pan Y, Lane WS, Chen J
  Title
ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
  Journal
EMBO J 24:3411-22 (2005)
  Sequence
[hsa:4194]
Reference
  Authors
Jin Y, Dai MS, Lu SZ, Xu Y, Luo Z, Zhao Y, Lu H
  Title
14-3-3gamma binds to MDMX that is phosphorylated by UV-activated Chk1, resulting  in p53 activation.
  Journal
EMBO J 25:1207-18 (2006)
  Sequence
[hsa:4194]

DBGET integrated database retrieval system