KEGG   ORTHOLOGY: K10144Help
Entry
K10144                      KO                                     

Name
RCHY1, PIRH2
Definition
RING finger and CHY zinc finger domain-containing protein 1 [EC:6.3.2.19]
Pathway
p53 signaling pathway
Ubiquitin mediated proteolysis
Measles
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1
 Cellular Processes
  Cell growth and death
   04115 p53 signaling pathway
    K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1
 Human Diseases
  Infectious diseases
   05162 Measles
    K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  single Ring-finger type E3
   Other single Ring-finger type E3
    K10144  RCHY1, PIRH2; RING finger and CHY zinc finger domain-containing protein 1
BRITE hierarchy
Genes
HSA: 
25898(RCHY1)
PTR: 
461248(RCHY1)
PPS: 
100970552(RCHY1)
GGO: 
101142111(RCHY1)
PON: 
100446564(RCHY1)
MCC: 
701580(RCHY1)
MCF: 
102144301(RCHY1)
MMU: 
68098(Rchy1)
RNO: 
289508(Rchy1)
CGE: 
HGL: 
101700191(Rchy1)
TUP: 
102478505(RCHY1)
CFA: 
612746(RCHY1)
AML: 
FCA: 
101080785(RCHY1)
PTG: 
102955633(RCHY1)
BTA: 
540733(RCHY1)
BOM: 
102272825(RCHY1)
PHD: 
102334266(RCHY1)
CHX: 
102181578(RCHY1)
SSC: 
CFR: 
102513863(RCHY1)
ECB: 
100057332(RCHY1)
MYB: 
102260347(RCHY1)
MYD: 
102753824(RCHY1)
PALE: 
102883456(RCHY1)
MDO: 
100024151(RCHY1)
SHR: 
OAA: 
100079678(RCHY1)
GGA: 
771726(RCHY1)
TGU: 
100219468(RCHY1)
FAB: 
101820010(RCHY1)
PHI: 
102110475(RCHY1)
APLA: 
101802500(RCHY1)
FPG: 
101921704(RCHY1)
FCH: 
102052138(RCHY1)
CLV: 
102090104(RCHY1)
ASN: 
102379175(RCHY1)
PSS: 
102452832(RCHY1)
CMY: 
102947239(RCHY1)
XLA: 
496013(rchy1)
XTR: 
496979(rchy1)
DRE: 
321875(rchy1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CIN: 
DPE: 
DGR: 
DMO: 
DVI: 
AME: 
408590(GB12346)
NVI: 
TCA: 
BMOR: 
NVE: 
HMG: 
AQU: 
ATH: 
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
MTR: 
CAM: 
FVE: 
CSV: 
RCU: 
POP: 
POPTR_0006s12360g POPTR_0006s26180g(POPTRDRAFT_654056) POPTR_0008s20990g(POPTRDRAFT_565361) POPTR_0009s01110g(POPTRDRAFT_558319) POPTR_0014s12890g(POPTRDRAFT_245964) POPTR_0018s01000g
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os01t0719100-01(Os01g0719100) Os03t0348900-01(Os03g0348900) Os10t0456800-01(Os10g0456800) Os12t0538500-01(Os12g0538500)
OBR: 
BDI: 
SBI: 
SORBI_01g020210(SORBIDRAFT_01g020210) SORBI_01g035440(SORBIDRAFT_01g035440) SORBI_01g047160(SORBIDRAFT_01g047160) SORBI_08g017080(SORBIDRAFT_08g017080)
ZMA: 
SITA: 
ATR: 
s00057p00167230(AMTR_s00057p00167230) s00102p00024480(AMTR_s00102p00024480) s00142p00031670(AMTR_s00142p00031670)
SMO: 
PPP: 
CRE: 
VCN: 
CSL: 
CVR: 
CCP: 
ECU: 
EIN: 
EHE: 
MBR: 
DDI: 
DPP: 
DFA: 
ACAN: 
PTM: 
PTI: 
TPS: 
PIF: 
GTT: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Shloush J, Vlassov JE, Engson I, Duan S, Saridakis V, Dhe-Paganon S, Raught B, Sheng Y, Arrowsmith CH
  Title
Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.
  Journal
J Biol Chem 286:4796-808 (2011)
Reference
  Authors
Logan IR, Gaughan L, McCracken SR, Sapountzi V, Leung HY, Robson CN
  Title
Human PIRH2 enhances androgen receptor signaling through inhibition of histone deacetylase 1 and is overexpressed in prostate cancer.
  Journal
Mol Cell Biol 26:6502-10 (2006)

DBGET integrated database retrieval system