KEGG   ORTHOLOGY: K10159Help
Entry
K10159                      KO                                     

Name
TLR2, CD282
Definition
toll-like receptor 2
Pathway
ko04145  Phagosome
ko04151  PI3K-Akt signaling pathway
ko04620  Toll-like receptor signaling pathway
ko05134  Legionellosis
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05162  Measles
ko05168  Herpes simplex infection
ko05205  Proteoglycans in cancer
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
Module
M00686  Toll-like receptor signaling
Disease
H00344  Leprosy
H01358  Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K10159  TLR2, CD282; toll-like receptor 2
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K10159  TLR2, CD282; toll-like receptor 2
  Immune diseases
   05323 Rheumatoid arthritis
    K10159  TLR2, CD282; toll-like receptor 2
   05321 Inflammatiory bowel disease (IBD)
    K10159  TLR2, CD282; toll-like receptor 2
  Infectious diseases
   05134 Legionellosis
    K10159  TLR2, CD282; toll-like receptor 2
   05152 Tuberculosis
    K10159  TLR2, CD282; toll-like receptor 2
   05162 Measles
    K10159  TLR2, CD282; toll-like receptor 2
   05161 Hepatitis B
    K10159  TLR2, CD282; toll-like receptor 2
   05168 Herpes simplex infection
    K10159  TLR2, CD282; toll-like receptor 2
   05146 Amoebiasis
    K10159  TLR2, CD282; toll-like receptor 2
   05144 Malaria
    K10159  TLR2, CD282; toll-like receptor 2
   05145 Toxoplasmosis
    K10159  TLR2, CD282; toll-like receptor 2
   05140 Leishmaniasis
    K10159  TLR2, CD282; toll-like receptor 2
   05142 Chagas disease (American trypanosomiasis)
    K10159  TLR2, CD282; toll-like receptor 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K10159  TLR2, CD282; toll-like receptor 2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    K10159  TLR2, CD282; toll-like receptor 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   K10159  TLR2, CD282; toll-like receptor 2
Pattern recognition receptors [BR:ko04054]
 Membrane-bound pattern recognition receptors
  Toll-like receptors
   K10159  TLR2, CD282; toll-like receptor 2
CD molecules [BR:ko04090]
 Proteins
  K10159  CD282, TLR2; toll-like receptor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K10159  TLR2, CD282; toll-like receptor 2
BRITE hierarchy
Genes
HSA: 7097(TLR2)
PTR: 471325(TLR2)
PPS: 100994768(TLR2)
GGO: 101128447(TLR2)
PON: 100456464(TLR2)
NLE: 100604724(TLR2) 101178195
MCC: 574290(TLR2)
MCF: 102146068(TLR2)
CSAB: 103236415
RRO: 104677747(TLR2)
RBB: 108529041(TLR2)
CJC: 100404611(TLR2)
SBQ: 101045472(TLR2)
MMU: 24088(Tlr2)
RNO: 310553(Tlr2)
CGE: 100771475(Tlr2)
NGI: 103750991(Tlr2)
HGL: 101724657(Tlr2)
CCAN: 109701180(Tlr2)
OCU: 100009578(TLR2)
TUP: 102482498(TLR2)
CFA: 448807(TLR2)
AML: 100465129(TLR2)
ORO: 101363280(TLR2) 101367407
FCA: 493797(TLR2)
AJU: 106982476(TLR2) 106989776
BTA: 281534(TLR2)
BOM: 102268835(TLR2)
BIU: 109571498(TLR2)
PHD: 102330806(TLR2)
CHX: 100860747(TLR2)
OAS: 554262(TLR2)
SSC: 396623(TLR2)
CFR: 102523960(TLR2)
CDK: 105099662(TLR2) 105106680
BACU: 102998386(TLR2) 103003817
LVE: 103090179
ECB: 100009701(TLR2)
EPZ: 103553736(TLR2)
EAI: 106821799(TLR2)
MYB: 102256005(TLR2)
MYD: 102761137(TLR2)
HAI: 109382017(TLR2)
RSS: 109442125(TLR2)
PALE: 102893057(TLR2)
LAV: 100654442(TLR2)
TMU: 101342847
MDO: 100024558(TLR2)
SHR: 100932981(TLR2)
OAA: 100081248(TLR2)
GGA: 100858824(TLR2L) 374141(TLR2A) 769014(TLR2B)
MGP: 104910743(TLR2)
APLA: 101791786(TLR2) 101805243
FAB: 101811742 101811943(TLR2)
PHI: 102104379 102104560(TLR2)
PMAJ: 107202976(TLR2)
CCW: 104697168(TLR2)
CLV: 102084454 102084767(TLR2)
AMJ: 102571171(CD14) 106740518(TLR2)
CPIC: 101932351(TLR2) 101932616 101937770(CD14)
PVT: 110072767(TLR2) 110082123
XTR: 100485512(tlr14.2) 100485771(tlr2) 100485927 101734746
DRE: 403125(tlr2)
SRX: 107722930
SANH: 107702532(tlr2)
SGH: 107590711
IPU: 108258959(tlr2)
TRU: 101068557(tlr2)
LCO: 104934739(tlr2) 104938453
PRET: 103460805(tlr2) 103480941
NFU: 107395103
CSEM: 103388693
HCQ: 109512204
BPEC: 110160272
SASA: 106608430
ELS: 105030906(tlr2)
SFM: 108926796
LCM: 102350366 102367073(TLR2)
LAK: 106180703
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9596645
  Authors
Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS
  Title
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
  Journal
Blood 91:4020-7 (1998)
  Sequence
[hsa:7097]
Reference
  Authors
Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, Han SH, Lee H, Paik SG, Lee JO
  Title
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
  Journal
Immunity 31:873-84 (2009)
DOI:10.1016/j.immuni.2009.09.018
  Sequence
[mmu:24088]

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