KEGG   ORTHOLOGY: K10159Help
Entry
K10159                      KO                                     

Name
TLR2, CD282
Definition
toll-like receptor 2
Pathway
Phagosome
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis B
Measles
Herpes simplex infection
Proteoglycans in cancer
Inflammatory bowel disease (IBD)
Rheumatoid arthritis
Module
M00686  
Toll-like receptor signaling
Disease
H00344  
Leprosy
H01358  
Atopic dermatitis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04151 PI3K-Akt signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K10159  TLR2, CD282; toll-like receptor 2
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K10159  TLR2, CD282; toll-like receptor 2
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K10159  TLR2, CD282; toll-like receptor 2
  Immune diseases
   05323 Rheumatoid arthritis
    K10159  TLR2, CD282; toll-like receptor 2
   05321 Inflammatiory bowel disease (IBD)
    K10159  TLR2, CD282; toll-like receptor 2
  Infectious diseases
   05134 Legionellosis
    K10159  TLR2, CD282; toll-like receptor 2
   05152 Tuberculosis
    K10159  TLR2, CD282; toll-like receptor 2
   05162 Measles
    K10159  TLR2, CD282; toll-like receptor 2
   05161 Hepatitis B
    K10159  TLR2, CD282; toll-like receptor 2
   05168 Herpes simplex infection
    K10159  TLR2, CD282; toll-like receptor 2
   05146 Amoebiasis
    K10159  TLR2, CD282; toll-like receptor 2
   05144 Malaria
    K10159  TLR2, CD282; toll-like receptor 2
   05145 Toxoplasmosis
    K10159  TLR2, CD282; toll-like receptor 2
   05140 Leishmaniasis
    K10159  TLR2, CD282; toll-like receptor 2
   05142 Chagas disease (American trypanosomiasis)
    K10159  TLR2, CD282; toll-like receptor 2
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00686  Toll-like receptor signaling
     K10159  TLR2, CD282; toll-like receptor 2
Membrane trafficking [BR:ko04131]
 Endocytosis
  Phagocytosis
   Toll-like receptors
    K10159  TLR2, CD282; toll-like receptor 2
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of breast milk
   K10159  TLR2, CD282; toll-like receptor 2
CD molecules [BR:ko04090]
 Proteins
  K10159  CD282, TLR2; toll-like receptor 2
Glycosaminoglycan binding proteins [BR:ko00536]
 Hyaluronan
  Cell surface receptors
   K10159  TLR2, CD282; toll-like receptor 2
BRITE hierarchy
Genes
HSA: 
7097(TLR2)
PTR: 
471325(TLR2)
PPS: 
100994768(TLR2)
GGO: 
101128447(TLR2)
PON: 
100456464(TLR2)
NLE: 
MCC: 
574290(TLR2)
MCF: 
102146068(TLR2)
CSAB: 
RRO: 
104677747(TLR2)
RBB: 
108529041(TLR2)
CJC: 
100404611(TLR2)
SBQ: 
101045472(TLR2)
MMU: 
24088(Tlr2)
RNO: 
310553(Tlr2)
CGE: 
100771475(Tlr2)
NGI: 
103750991(Tlr2)
HGL: 
101724657(Tlr2)
CCAN: 
109701180(Tlr2)
OCU: 
100009578(TLR2)
TUP: 
102482498(TLR2)
CFA: 
448807(TLR2)
AML: 
100465129(TLR2)
UMR: 
FCA: 
493797(TLR2)
PTG: 
AJU: 
BTA: 
281534(TLR2)
BOM: 
102268835(TLR2)
BIU: 
109571498(TLR2)
PHD: 
102330806(TLR2)
CHX: 
100860747(TLR2)
OAS: 
554262(TLR2)
SSC: 
396623(TLR2)
CFR: 
102523960(TLR2)
CDK: 
BACU: 
LVE: 
ECB: 
100009701(TLR2)
EPZ: 
103553736(TLR2)
EAI: 
106821799(TLR2)
MYB: 
102256005(TLR2)
MYD: 
102761137(TLR2)
HAI: 
109382017(TLR2)
RSS: 
109442125(TLR2)
PALE: 
102893057(TLR2)
LAV: 
100654442(TLR2)
MDO: 
100024558(TLR2)
SHR: 
100932981(TLR2)
OAA: 
100081248(TLR2)
GGA: 
100858824(TLR2L) 374141(TLR2A) 769014(TLR2B)
MGP: 
104910743(TLR2)
CJO: 
APLA: 
ACYG: 
TGU: 
GFR: 
FAB: 
PHI: 
CCW: 
104697168(TLR2)
FPG: 
FCH: 
CLV: 
AAM: 
ASN: 
AMJ: 
102571171(CD14) 106740518(TLR2)
PSS: 
CMY: 
CPIC: 
ACS: 
PBI: 
GJA: 
XLA: 
XTR: 
NPR: 
DRE: 
403125(tlr2)
SRX: 
SANH: 
107702532(tlr2)
SGH: 
IPU: 
108258959(tlr2)
TRU: 
101068557(tlr2)
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
CSEM: 
LCF: 
SASA: 
ELS: 
105030906(tlr2)
SFM: 
LCM: 
CMK: 
CRG: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9596645
  Authors
Chaudhary PM, Ferguson C, Nguyen V, Nguyen O, Massa HF, Eby M, Jasmin A, Trask BJ, Hood L, Nelson PS
  Title
Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
  Journal
Blood 91:4020-7 (1998)
  Sequence
[hsa:7097]
Reference
  Authors
Kang JY, Nan X, Jin MS, Youn SJ, Ryu YH, Mah S, Han SH, Lee H, Paik SG, Lee JO
  Title
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.
  Journal
Immunity 31:873-84 (2009)
DOI:10.1016/j.immuni.2009.09.018
  Sequence
[mmu:24088]

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