KEGG   ORTHOLOGY: K10160Help
Entry
K10160                      KO                                     
Name
TLR4
Definition
toll-like receptor 4
Pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phagosome
PI3K-Akt signaling pathway
Toll-like receptor signaling pathway
Pathogenic Escherichia coli infection
Salmonella infection
Pertussis
Legionellosis
Leishmaniasis
Chagas disease (American trypanosomiasis)
Malaria
Toxoplasmosis
Amoebiasis
Tuberculosis
Hepatitis B
Measles
Influenza A
Proteoglycans in cancer
Rheumatoid arthritis
Disease
H00821  
Macular degeneration
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K10160  TLR4; toll-like receptor 4
   04066 HIF-1 signaling pathway
    K10160  TLR4; toll-like receptor 4
   04151 PI3K-Akt signaling pathway
    K10160  TLR4; toll-like receptor 4
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K10160  TLR4; toll-like receptor 4
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K10160  TLR4; toll-like receptor 4
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K10160  TLR4; toll-like receptor 4
  Immune diseases
   05323 Rheumatoid arthritis
    K10160  TLR4; toll-like receptor 4
  Infectious diseases
   05130 Pathogenic Escherichia coli infection
    K10160  TLR4; toll-like receptor 4
   05132 Salmonella infection
    K10160  TLR4; toll-like receptor 4
   05133 Pertussis
    K10160  TLR4; toll-like receptor 4
   05134 Legionellosis
    K10160  TLR4; toll-like receptor 4
   05152 Tuberculosis
    K10160  TLR4; toll-like receptor 4
   05162 Measles
    K10160  TLR4; toll-like receptor 4
   05164 Influenza A
    K10160  TLR4; toll-like receptor 4
   05161 Hepatitis B
    K10160  TLR4; toll-like receptor 4
   05146 Amoebiasis
    K10160  TLR4; toll-like receptor 4
   05144 Malaria
    K10160  TLR4; toll-like receptor 4
   05145 Toxoplasmosis
    K10160  TLR4; toll-like receptor 4
   05140 Leishmaniasis
    K10160  TLR4; toll-like receptor 4
   05142 Chagas disease (American trypanosomiasis)
    K10160  TLR4; toll-like receptor 4
Cellular antigens [BR:ko04090]
 Proteins
  K10160  CD284, TLR4; toll-like receptor 4
BRITE hierarchy
Genes
HSA: 
7099(TLR4)
PTR: 
743242(TLR4)
PPS: 
100980644(TLR4)
GGO: 
PON: 
100457237(TLR4)
MCC: 
574360(TLR4)
MMU: 
21898(Tlr4)
RNO: 
29260(Tlr4)
CFA: 
403417(TLR4)
AML: 
FCA: 
493698(TLR4)
BTA: 
281536(TLR4)
SSC: 
399541(TLR4)
ECB: 
100066890(TLR4)
MDO: 
100014467
SHR: 
100927125(TLR4)
OAA: 
100077705
GGA: 
417241(TLR4)
MGP: 
100540712
TGU: 
100216357(TLR4)
ACS: 
100559216
DRE: 
403131(tlr4ba) 403132(tlr4bb) 795671
TCA: 
662131
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Anand RJ, Kohler JW, Cavallo JA, Li J, Dubowski T, Hackam DJ
  Title
Toll-like receptor 4 plays a role in macrophage phagocytosis during peritoneal sepsis.
  Journal
J Pediatr Surg 42:927-32; discussion 933 (2007)
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