KEGG   ORTHOLOGY: K10592Help
Entry
K10592                      KO                                     
Name
HUWE1, MULE, ARF-BP1
Definition
E3 ubiquitin-protein ligase HUWE1 [EC:6.3.2.19]
Pathway
Ubiquitin mediated proteolysis
Disease
H00658  
Syndromic X-linked mental retardation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K10592  HUWE1, MULE, ARF-BP1; E3 ubiquitin-protein ligase HUWE1
BRITE hierarchy
Genes
HSA: 
10075(HUWE1)
PTR: 
465650(HUWE1)
PPS: 
100972394(HUWE1)
GGO: 
101135087(HUWE1)
PON: 
100460369(HUWE1)
MCC: 
700136(HUWE1)
MMU: 
59026(Huwe1)
CFA: 
480931(HUWE1)
AML: 
100483129(HUWE1)
FCA: 
101091091(HUWE1)
BTA: 
511826(HUWE1)
SSC: 
100517442
ECB: 
100060375(HUWE1)
MDO: 
100010537(HUWE1)
SHR: 
100914679
ACS: 
100563451(huwe1)
XTR: 
100489531
DRE: 
559439(huwe1)
TRU: 
101065803
OLA: 
101170019
BFO: 
BRAFLDRAFT_133792
SPU: 
575742(huwe1)
DME: 
Dmel_CG8184
DPO: 
Dpse_GA22604
DAN: 
Dana_GF21923
DER: 
Dere_GG17901
DPE: 
Dper_GL16485
DSE: 
Dsec_GM22568
DSI: 
Dsim_GD17230
DWI: 
Dwil_GK19776
DYA: 
Dyak_GE17209
DGR: 
Dgri_GH24543
DMO: 
Dmoj_GI16351
DVI: 
Dvir_GJ16896 Dvir_GJ16898
NVI: 
100123214(Huwe1)
TCA: 
657452(HUWE1)
PHU: 
Phum_PHUM461390
ISC: 
IscW_ISCW017075
CEL: 
CELE_Y67D8C.5(eel-1)
CBR: 
CBG03363(Cbr-eel-1)
BMY: 
Bm1_31595
TSP: 
Tsp_06790
SMM: 
Smp_167680.2 Smp_167690
NVE: 
NEMVE_v1g125752
HMG: 
100203526
TAD: 
TRIADDRAFT_37508
AQU: 
100641998
ATH: 
AT1G55860(UPL1) AT1G70320(UPL2)
ALY: 
ARALYDRAFT_474651(UPL1) ARALYDRAFT_684483
GMX: 
100777899 100788161 100801545 100802630 100819012
MTR: 
MTR_5g066710
CSV: 
101207789 101223063 101225714
RCU: 
RCOM_0482820 RCOM_0522490
POP: 
POPTR_1093798 POPTR_815774 POPTR_830264
VVI: 
100246297 100255704
OSA: 
4346521 4346522 4352108
DOSA: 
Os09t0252700-01(Os09g0252700) Os09t0252800-01(Os09g0252800) Os12t0428600-01(Os12g0428600)
BDI: 
100821130
SBI: 
SORBI_08g012560(SORBIDRAFT_08g012560)
ZMA: 
100304346
SMO: 
SELMODRAFT_154179(UPL1-2) SELMODRAFT_160088(UPL1-1)
PPP: 
PHYPADRAFT_137606
CRE: 
CHLREDRAFT_129201
VCN: 
VOLCADRAFT_75266
CME: 
CMR077C
SCE: 
YDR457W(TOM1)
AGO: 
AGOS_AER304C
ERC: 
Ecym_4111
KLA: 
KLLA0B01804g
LTH: 
KLTH0G04884g
PPA: 
PAS_chr3_0044
VPO: 
Kpol_1023p70
ZRO: 
ZYRO0D13794g
CGR: 
CAGL0K06303g
NCS: 
NCAS_0F01360(NCAS0F01360)
NDI: 
NDAI_0H01870(NDAI0H01870)
TPF: 
TPHA_0K00280(TPHA0K00280)
TBL: 
TBLA_0E02870(TBLA0E02870)
TDL: 
TDEL_0A04410(TDEL0A04410)
KAF: 
KAFR_0I01130(KAFR0I01130)
DHA: 
DEHA2G05544g
PIC: 
PICST_81688(TOM12)
PGU: 
PGUG_02920
LEL: 
LELG_01304
CAL: 
CaO19.13198(TOM1) CaO19.5776(TOM1) CaO19.8529(TOM1) CaO19.911(TOM1)
CTP: 
CTRG_01307
CDU: 
CD36_17950
COT: 
CORT_0A11060
YLI: 
YALI0B05940g
CLU: 
CLUG_01571 CLUG_01572
NCR: 
NCU08501
SMP: 
SMAC_06263
PAN: 
PODANSg6603
TTT: 
THITE_2123882
MTM: 
MYCTH_2312159
MGR: 
MGG_03252
FGR: 
FG00633.1
NHE: 
NECHADRAFT_31398
VAL: 
VDBG_05258
SSL: 
SS1G_10713
BFU: 
BC1G_04261
ANI: 
AN1966.2
NFI: 
NFIA_105310
AFM: 
AFUA_4G10780
AOR: 
AOR_1_2024154(AO090003001136)
ANG: 
ANI_1_964184(An04g05870)
AFV: 
AFLA_026810
ACT: 
ACLA_049950
PCS: 
Pc22g06970
CIM: 
CIMG_01480
CPW: 
CPC735_049610
PBL: 
PAAG_02632
URE: 
UREG_05115
ABE: 
ARB_02273
TVE: 
TRV_04980
AJE: 
HCAG_01668
PNO: 
SNOG_15653
PTE: 
PTT_06702
ZTR: 
MYCGRDRAFT_98370
TML: 
GSTUM_00000174001
SPO: 
SPAC19D5.04(ptr1)
CNE: 
CNI01260
CNB: 
CNBH1200
CGI: 
CGB_H1790W
LBC: 
LACBIDRAFT_313667
CCI: 
CC1G_01887
SCM: 
SCHCODRAFT_58497
UMA: 
UM03442.1 UM05564.1
MGL: 
MGL_0055 MGL_2525
PGR: 
PGTG_00744
MBR: 
MONBRDRAFT_15591
NGR: 
NAEGRDRAFT_33035
DPP: 
DICPUDRAFT_39910
EHI: 
EHI_104570(415.t00009)
EDI: 
EDI_305290
PFA: 
MAL8P1.23
PFH: 
PFHG_04159
PYO: 
PY00959
PCB: 
PC301489.00.0
PBE: 
PB000644.01.0
PKN: 
PKH_050470
PVX: 
PVX_089055
PCY: 
PCYB_051510
CHO: 
Chro.30149
TGO: 
TGME49_095710
TET: 
TTHERM_00161820
PTM: 
GSPATT00006436001 GSPATT00011462001
TBR: 
Tb927.8.1590(Tb08.29O9.320)
TCR: 
508971.50
LMA: 
LMJF_07_0280
LIF: 
LINJ_07_0440
LDO: 
LDBPK_070440
LMI: 
LMXM_07_0280
LBZ: 
LBRM_07_0290
PTI: 
PHATRDRAFT_12562
TPS: 
THAPSDRAFT_33759
PIF: 
PITG_08025
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Parsons JL, Tait PS, Finch D, Dianova II, Edelmann MJ, Khoronenkova SV, Kessler BM, Sharma RA, McKenna WG, Dianov GL
  Title
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.
  Journal
EMBO J 28:3207-15 (2009)
DBGET integrated database retrieval system