KEGG   ORTHOLOGY: K10652Help
Entry
K10652                      KO                                     

Name
TRIM25, EFP
Definition
tripartite motif-containing protein 25 [EC:6.3.2.19]
Pathway
NF-kappa B signaling pathway
RIG-I-like receptor signaling pathway
Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
 Organismal Systems
  Immune system
   04622 RIG-I-like receptor signaling pathway
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
 Human Diseases
  Infectious diseases
   05164 Influenza A
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K10652  TRIM25, EFP; tripartite motif-containing protein 25
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  single Ring-finger type E3
   TRIM/RBCC proteins
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
BRITE hierarchy
Genes
HSA: 
7706(TRIM25)
PTR: 
455146(TRIM25)
PPS: 
100971009(TRIM25)
GGO: 
101151068(TRIM25)
PON: 
100440167(TRIM25)
MCC: 
MCF: 
102117091(TRIM25)
MMU: 
217069(Trim25)
RNO: 
494338(Trim25)
CGE: 
100765402(Trim25)
HGL: 
101710143(Trim25)
TUP: 
102491192(TRIM25)
CFA: 
491103(TRIM25)
FCA: 
101084663(TRIM25)
PTG: 
102949419(TRIM25)
BTA: 
510923(TRIM25)
BOM: 
102277633(TRIM25)
PHD: 
102344676(TRIM25)
CHX: 
102181625(TRIM25)
SSC: 
CFR: 
102516528(TRIM25)
BACU: 
103015462(TRIM25)
LVE: 
103090776(TRIM25)
ECB: 
100146440(TRIM25)
MYB: 
102252032(TRIM25)
MYD: 
102773217(TRIM25)
PALE: 
102879209(TRIM25)
MDO: 
100013883(TRIM25)
SHR: 
100928651(TRIM25)
OAA: 
100093428(COIL)
GGA: 
417401(TRIM25)
MGP: 
TGU: 
100221651(TRIM25)
FAB: 
101815485(TRIM25)
PHI: 
102100676(TRIM25)
APLA: 
101791574(TRIM25)
FPG: 
101923333(TRIM25)
FCH: 
102057184(TRIM25)
CLV: 
102084896(TRIM25)
ASN: 
AMJ: 
102558244(TRIM25)
PSS: 
102460037(TRIM25)
CMY: 
102947648(TRIM25)
ACS: 
PBI: 
103056401(TRIM25)
XLA: 
XTR: 
DRE: 
393144(trim25)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W
  Title
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
  Journal
PLoS Pathog 4:e16 (2008)
Reference
  Authors
Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU
  Title
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.
  Journal
Nature 446:916-920 (2007)

DBGET integrated database retrieval system