KEGG   ORTHOLOGY: K10652Help
Entry
K10652                      KO                                     
Name
TRIM25, EFP
Definition
tripartite motif-containing protein 25
Pathway
NF-kappa B signaling pathway
RIG-I-like receptor signaling pathway
Influenza A
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
 Organismal Systems
  Immune system
   04622 RIG-I-like receptor signaling pathway
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
 Human Diseases
  Infectious diseases
   05164 Influenza A
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  single Ring-finger type E3
   TRIM/RBCC proteins
    K10652  TRIM25, EFP; tripartite motif-containing protein 25
BRITE hierarchy
Genes
HSA: 
7706(TRIM25)
PTR: 
455146(TRIM25)
PPS: 
100971009(TRIM25)
GGO: 
101151068(TRIM25)
PON: 
100440167(TRIM25)
MCC: 
MMU: 
217069(Trim25)
RNO: 
494338(Trim25)
CFA: 
491103(TRIM25)
FCA: 
101084663(TRIM25)
BTA: 
510923(TRIM25)
SSC: 
100622285
ECB: 
100146440(TRIM25)
MDO: 
100013883(TRIM25)
SHR: 
100928651(TRIM25)
OAA: 
100093428
GGA: 
417401(TRIM25)
MGP: 
100548159
TGU: 
100221651(TRIM25)
ACS: 
100567794
XLA: 
100101308 446627
XTR: 
100490368 493235 733855
DRE: 
393144(trim25)
TRU: 
101076539
OLA: 
101157185
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Uchil PD, Quinlan BD, Chan WT, Luna JM, Mothes W
  Title
TRIM E3 ligases interfere with early and late stages of the retroviral life cycle.
  Journal
PLoS Pathog 4:e16 (2008)
Reference
  Authors
Gack MU, Shin YC, Joo CH, Urano T, Liang C, Sun L, Takeuchi O, Akira S, Chen Z, Inoue S, Jung JU
  Title
TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity.
  Journal
Nature 446:916-920 (2007)
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