KEGG   ORTHOLOGY: K10772Help
Entry
K10772                      KO                                     
Name
APEX2
Definition
AP endonuclease 2 [EC:4.2.99.18]
Pathway
Base excision repair
Module
M00296  
BER complex
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03410 Base excision repair
    K10772  APEX2; AP endonuclease 2
KEGG pathway modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Repair system
    M00296  BER complex [BR:ko03400]
     K10772  APEX2; AP endonuclease 2
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.99  Other carbon-oxygen lyases
    4.2.99.18  DNA-(apurinic or apyrimidinic site) lyase
     K10772  APEX2; AP endonuclease 2
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    AP endonucleases
     K10772  APEX2; AP endonuclease 2
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
27301(APEX2)
PTR: 
473625(APEX2)
PPS: 
100975705(APEX2)
GGO: 
101142413(APEX2)
PON: 
100434759(APEX2)
MCC: 
702084(APEX2)
MMU: 
77622(Apex2)
RNO: 
289662(Apex2) 317628(RGD1565983)
CFA: 
AML: 
FCA: 
101095317(APEX2)
BTA: 
511790(APEX2)
SSC: 
100519003
ECB: 
100062550
MDO: 
100012903
SHR: 
100927463(APEX2)
OAA: 
100079599
ACS: 
100567501
XLA: 
446614(apex2)
XTR: 
448512(apex2)
DRE: 
393115(apex2)
TRU: 
101076869
OLA: 
101166381
BFO: 
BRAFLDRAFT_124956
SPU: 
579199
ISC: 
IscW_ISCW010678
TSP: 
Tsp_03481
SMM: 
Smp_167500
NVE: 
NEMVE_v1g161616
HMG: 
100210591
TAD: 
TRIADDRAFT_19413
AQU: 
100633380
ATH: 
AT4G36050
ALY: 
ARALYDRAFT_491028
GMX: 
100781120
MTR: 
MTR_8g075810
CSV: 
101222374
RCU: 
RCOM_0870510
POP: 
POPTR_799764
VVI: 
100264349
OSA: 
4347697
DOSA: 
Os09t0536000-01(Os09g0536000)
BDI: 
100830878
SBI: 
SORBI_02g031100(SORBIDRAFT_02g031100)
SMO: 
SELMODRAFT_134604 SELMODRAFT_81439
PPP: 
PHYPADRAFT_96854
CRE: 
CHLREDRAFT_172466
VCN: 
VOLCADRAFT_118317
OLU: 
OSTLU_31440
OTA: 
Ot04g05410
CME: 
CMS149C
SCE: 
YBL019W(APN2)
AGO: 
AGOS_AFR016W
ERC: 
Ecym_6193
KLA: 
KLLA0E10473g
LTH: 
KLTH0H08250g
PPA: 
PAS_chr1-3_0055
VPO: 
Kpol_1007p2
ZRO: 
ZYRO0C13222g
CGR: 
CAGL0J04356g
NCS: 
NCAS_0B05590(NCAS0B05590)
NDI: 
NDAI_0B02930(NDAI0B02930)
TPF: 
TPHA_0H00210(TPHA0H00210)
TBL: 
TBLA_0A08780(TBLA0A08780)
TDL: 
TDEL_0B04460(TDEL0B04460)
KAF: 
KAFR_0C02810(KAFR0C02810)
DHA: 
DEHA2G11814g
PIC: 
PICST_28317(APN2)
PGU: 
PGUG_04297
LEL: 
LELG_01061
CAL: 
CaO19.1836(APN2) CaO19.9394(APN2)
CTP: 
CTRG_03279
CDU: 
CD36_09980
COT: 
CORT_0A11880
YLI: 
YALI0C07436g
CLU: 
CLUG_05063 CLUG_05065
NCR: 
NCU01961
SMP: 
SMAC_05405
PAN: 
PODANSg026
TTT: 
THITE_2111508
MTM: 
MYCTH_2298234
MGR: 
MGG_02980
FGR: 
FG08889.1
NHE: 
NECHADRAFT_78136
VAL: 
VDBG_01987
SSL: 
SS1G_04002
BFU: 
BC1G_15146
ANI: 
AN4736.2
NFI: 
NFIA_024380 NFIA_071080
AFM: 
AFUA_3G06180
AOR: 
AOR_1_156084(AO090020000091)
ANG: 
ANI_1_1326094(An11g10190)
AFV: 
AFLA_103190
ACT: 
ACLA_034130
PCS: 
Pc20g07790
CIM: 
CIMG_00405
CPW: 
CPC735_058050
PBL: 
PAAG_05877
URE: 
UREG_00453
ABE: 
ARB_07318
TVE: 
TRV_02049
AJE: 
HCAG_01173
PNO: 
SNOG_00377
PTE: 
PTT_09967
ZTR: 
MYCGRDRAFT_88442(APN2)
SPO: 
SPBC3D6.10(apn2)
CNE: 
CNI04070
CNB: 
CNBH3880
CGI: 
CGB_H3800W
PPL: 
POSPLDRAFT_31820
LBC: 
LACBIDRAFT_299606
CCI: 
CC1G_05939
SCM: 
SCHCODRAFT_81869
UMA: 
UM00618.1
MGL: 
MGL_3205
PIF: 
PITG_05586
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Burkovics P, Hajdu I, Szukacsov V, Unk I, Haracska L
  Title
Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease  activities of human Ape2 in repair of oxidative DNA damage.
  Journal
Nucleic Acids Res 37:4247-55 (2009)
Reference
  Authors
Fraser JL, Neill E, Davey S
  Title
Fission yeast Uve1 and Apn2 function in distinct oxidative damage repair pathways in vivo.
  Journal
DNA Repair (Amst) 2:1253-67 (2003)
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