KEGG   ORTHOLOGY: K10785Help
Entry
K10785                      KO                                     

Name
TRBV
Definition
T-cell receptor beta chain V region
Pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
Cell adhesion molecules (CAMs)
Antigen processing and presentation
Th1 and Th2 cell differentiation
Th17 cell differentiation
T cell receptor signaling pathway
Intestinal immune network for IgA production
Type I diabetes mellitus
Chagas disease (American trypanosomiasis)
Malaria
Staphylococcus aureus infection
Measles
HTLV-I infection
Transcriptional misregulation in cancer
Asthma
Autoimmune thyroid disease
Inflammatory bowel disease (IBD)
Systemic lupus erythematosus
Rheumatoid arthritis
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04015 Rap1 signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04064 NF-kappa B signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04020 Calcium signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
  Signaling molecules and interaction
   04514 Cell adhesion molecules (CAMs)
    K10785  TRBV; T-cell receptor beta chain V region
 Organismal Systems
  Immune system
   04612 Antigen processing and presentation
    K10785  TRBV; T-cell receptor beta chain V region
   04660 T cell receptor signaling pathway
    K10785  TRBV; T-cell receptor beta chain V region
   04658 Th1 and Th2 cell differentiation
    K10785  TRBV; T-cell receptor beta chain V region
   04659 Th17 cell differentiation
    K10785  TRBV; T-cell receptor beta chain V region
   04672 Intestinal immune network for IgA production
    K10785  TRBV; T-cell receptor beta chain V region
 Human Diseases
  Cancers
   05202 Transcriptional misregulation in cancers
    K10785  TRBV; T-cell receptor beta chain V region
  Immune diseases
   05310 Asthma
    K10785  TRBV; T-cell receptor beta chain V region
   05322 Systemic lupus erythematosus
    K10785  TRBV; T-cell receptor beta chain V region
   05323 Rheumatoid arthritis
    K10785  TRBV; T-cell receptor beta chain V region
   05320 Autoimmune thyroid disease
    K10785  TRBV; T-cell receptor beta chain V region
   05321 Inflammatiory bowel disease (IBD)
    K10785  TRBV; T-cell receptor beta chain V region
   05330 Allograft rejection
    K10785  TRBV; T-cell receptor beta chain V region
   05332 Graft-versus-host disease
    K10785  TRBV; T-cell receptor beta chain V region
  Cardiovascular diseases
   05416 Viral myocarditis
    K10785  TRBV; T-cell receptor beta chain V region
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    K10785  TRBV; T-cell receptor beta chain V region
  Infectious diseases
   05150 Staphylococcus aureus infection
    K10785  TRBV; T-cell receptor beta chain V region
   05166 HTLV-I infection
    K10785  TRBV; T-cell receptor beta chain V region
   05162 Measles
    K10785  TRBV; T-cell receptor beta chain V region
   05144 Malaria
    K10785  TRBV; T-cell receptor beta chain V region
   05142 Chagas disease (American trypanosomiasis)
    K10785  TRBV; T-cell receptor beta chain V region
BRITE hierarchy
Other DBs
GO: 
Genes
PTR: 
100613861(BV10-1) 100615597(BV7-9)
CSAB: 
CJC: 
100896470(TRBV7-9)
SBQ: 
CGE: 
HGL: 
TUP: 
AJU: 
BTA: 
100300510(TCRB) 509513(TCRB)
SSC: 
MYD: 
PALE: 
MDO: 
PHI: 
FPG: 
ACS: 
PBI: 
XLA: 
LCO: 
MZE: 
OLA: 
LCM: 
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TaxonomyKoalaUniProt
Reference
  Authors
Jackson AM, Krangel MS
  Title
Turning T-cell receptor beta recombination on and off: more questions than answers.
  Journal
Immunol Rev 209:129-41 (2006)
DOI:10.1111/j.0105-2896.2006.00342.x
Reference
  Authors
Krangel MS
  Title
Mechanics of T cell receptor gene rearrangement.
  Journal
Curr Opin Immunol 21:133-9 (2009)
DOI:10.1016/j.coi.2009.03.009

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