KEGG   ORTHOLOGY: K10790Help
Entry
K10790                      KO                                     

Name
TREX1
Definition
three prime repair exonuclease 1 [EC:3.1.11.2]
Pathway
Cytosolic DNA-sensing pathway
Disease
H00290  
Aicardi-Goutieres Syndrome (AGS)
H00291  
Familial chilblain lupus (FCL)
H01000  
Retinal vasculopathy with cerebral leukodystrophy (RVCL)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04623 Cytosolic DNA-sensing pathway
    K10790  TREX1; three prime repair exonuclease 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.11  Exodeoxyribonucleases producing 5'-phosphomonoesters
    3.1.11.2  exodeoxyribonuclease III
     K10790  TREX1; three prime repair exonuclease 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  Other factors with a suspected DNA repair function
   Nucleases
    K10790  TREX1; three prime repair exonuclease 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
11277(TREX1)
PTR: 
742742(TREX1)
PPS: 
100982424(TREX1)
GGO: 
101148143(TREX1)
PON: 
100452811(TREX1)
NLE: 
100591582(TREX1)
MCC: 
100429168(TREX1)
MCF: 
102145869(TREX1)
CSAB: 
103227588(TREX1)
RRO: 
104667839(TREX1)
RBB: 
108527023(TREX1)
CJC: 
100385398(TREX1)
SBQ: 
101042042(TREX1)
MMU: 
22040(Trex1)
RNO: 
100049583(Trex1)
CGE: 
100761854(Trex1)
NGI: 
103750224(Trex1)
HGL: 
101715376(Trex1)
CCAN: 
109695273(Trex1)
OCU: 
100355546(TREX1)
TUP: 
102468212(TREX1)
CFA: 
102155466(TREX1)
AML: 
100476000(TREX1)
UMR: 
103674850(TREX1)
FCA: 
101098935(TREX1)
PTG: 
102964735(TREX1)
AJU: 
106979179(TREX1)
BTA: 
282099(TREX1)
BOM: 
102271118(TREX1)
BIU: 
109576261(TREX1)
CHX: 
102189528(TREX1)
OAS: 
101119766(TREX1)
SSC: 
100155669(TREX1)
CFR: 
102522505(TREX1)
CDK: 
105087958(TREX1)
BACU: 
103013392(TREX1)
LVE: 
103087946(TREX1)
ECB: 
100063767(TREX1)
EPZ: 
103556025(TREX1)
EAI: 
106821772(TREX1)
MYD: 
102761907(TREX1)
HAI: 
109377922(TREX1)
RSS: 
109443496(TREX1)
PALE: 
102883126(TREX1)
LAV: 
100675657(TREX1)
MDO: 
100023478(TREX1)
SHR: 
105749561(TREX1)
OAA: 
100078153(TREX1)
AAM: 
106486659(TREX1)
ACS: 
100561159(trex1)
PVT: 
GJA: 
107115530(TREX1)
BFO: 
CIN: 
SPU: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD23197(Dsim_GD23197)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
TCA: 
BMOR: 
PHU: 
DPX: 
ISC: 
LGI: 
CRG: 
OBI: 
SMM: 
SHX: 
OVI: 
NVE: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Mazur DJ, Perrino FW
  Title
Identification and expression of the TREX1 and TREX2 cDNA sequences encoding mammalian 3'-->5' exonucleases.
  Journal
J Biol Chem 274:19655-60 (1999)
DOI:10.1074/jbc.274.28.19655
  Sequence
[hsa:11277] [mmu:22040]

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