KEGG ORTHOLOGY: K10844

ORTHOLOGY: K10844

Entry

K10844 KO

Name

ERCC2, XPD

Definition

DNA excision repair protein ERCC-2 [EC:3.6.4.12]

Pathway

ko03022	Basal transcription factors
ko03420	Nucleotide excision repair

Module

M00290

Holo-TFIIH complex

Disease

H00403

Disorders of nucleotide excision repair

Brite

KEGG Orthology (KO) [BR:ko00001]
Genetic Information Processing
  Transcription
   03022 Basal transcription factors
    K10844  ERCC2, XPD; DNA excision repair protein ERCC-2
  Replication and repair
   03420 Nucleotide excision repair
    K10844  ERCC2, XPD; DNA excision repair protein ERCC-2
KEGG pathway modules [BR:ko00002]
Structural complex
  Genetic information processing
   Repair system
    M00290  Holo-TFIIH complex [BR:ko03021 ko03400]
     K10844  ERCC2, XPD; DNA excision repair protein ERCC-2
Enzymes [BR:ko01000]
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.12  DNA helicase
     K10844  ERCC2, XPD; DNA excision repair protein ERCC-2
Transcription machinery [BR:ko03021]
Eukaryotic type
  RNA polymerase II system
   Basal transcription factors
    TFIIH
     K10844  ERCC2, XPD; DNA excision repair protein ERCC-2
DNA repair and recombination proteins [BR:ko03400]
Eukaryotic Type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TFIIH complex
     K10844  ERCC2, XPD; DNA excision repair protein ERCC-2

Other DBs

GO:

0043139

Genes

HSA:	2068(ERCC2)
PTR:	456124(ERCC2)
PPS:	100990628(ERCC2)
GGO:	101125820(ERCC2)
PON:	100456938
MCC:	715485
MMU:	13871(Ercc2)
RNO:	308415(Ercc2)
CFA:	493995(ERCC2)
FCA:	101095702(ERCC2)
BTA:	100125238(ERCC2)
SSC:	100049685(ERCC2)
ECB:	100070804
MDO:	100012006
SHR:	100929325(ERCC2)
OAA:	100090468
XTR:	493493(ercc2)
DRE:	393900(ercc2)
TRU:	101077267
OLA:	101163020
BFO:	BRAFLDRAFT_286830
CIN:	100177945
SPU:	575323(ercc2)
DME:	Dmel_CG9433(Xpd)
DPO:	Dpse_GA25100
DAN:	Dana_GF11940
DER:	Dere_GG22096
DPE:	Dper_GL10160
DSE:	Dsec_GM15813
DSI:	Dsim_GD11571
DWI:	Dwil_GK21904
DYA:	Dyak_GE12176
DGR:	Dgri_GH20727
DMO:	Dmoj_GI20811
DVI:	Dvir_GJ20544
AGA:	AgaP_AGAP002988
AAG:	AaeL_AAEL000404
CQU:	CpipJ_CPIJ018703
AME:	412700(Xpd)
NVI:	100121723(NV11946)
TCA:	659447
API:	100167387
PHU:	Phum_PHUM583990
ISC:	IscW_ISCW000859
CEL:	CELE_Y50D7A.2(Y50D7A.2)
CBR:	CBG15713
BMY:	Bm1_45675
TSP:	Tsp_03297
SMM:	Smp_095370
NVE:	NEMVE_v1g180316
HMG:	100200345
TAD:	TRIADDRAFT_50379
AQU:	100640621
ATH:	AT1G03190(UVH6)
ALY:	ARALYDRAFT_470299
GMX:	100806384
RCU:	RCOM_0558550
POP:	POPTR_551188
VVI:	100240869
OSA:	4337788
BDI:	100833387
SBI:	SORBI_09g003450(SORBIDRAFT_09g003450)
ZMA:	100285960
SMO:	SELMODRAFT_269587
PPP:	PHYPADRAFT_217649
CRE:	CHLREDRAFT_100548
VCN:	VOLCADRAFT_59582
OLU:	OSTLU_26944
OTA:	Ot12g02930
CME:	CMP065C
SCE:	YER171W(RAD3)
AGO:	AGOS_AGR114C
KLA:	KLLA0C17776g
LTH:	KLTH0G14300g
PPA:	PAS_chr2-1_0797
VPO:	Kpol_1032p54
ZRO:	ZYRO0B11836g
CGR:	CAGL0L11924g
DHA:	DEHA2G12056g
PIC:	PICST_50344(RAD3)
PGU:	PGUG_04303
LEL:	LELG_02310
CAL:	CaO19.7119(RAD3) CaO19_7119(CaJ7_0007)
CTP:	CTRG_04956
CDU:	CD36_70260
YLI:	YALI0F20746g
CLU:	CLUG_05076
NCR:	NCU01625
SMP:	SMAC_02358
PAN:	PODANSg7073
MGR:	MGG_03132
FGR:	FG04295.1
NHE:	NECHADRAFT_105105
SSL:	SS1G_09606
BFU:	BC1G_12807
ANI:	AN9436.2
NFI:	NFIA_011560
AFM:	AFUA_1G13910
AOR:	AOR_1_846194(AO090012000485)
ANG:	ANI_1_992074(An08g07060)
AFV:	AFLA_017520
ACT:	ACLA_021550
PCS:	Pc16g12370
CIM:	CIMG_03377
CPW:	CPC735_008330
URE:	UREG_07205
ABE:	ARB_00089
TVE:	TRV_00914
PNO:	SNOG_09475
PTE:	PTT_20325
TML:	GSTUM_00010670001
SPO:	SPAC1D4.12(rad15)
CNE:	CNA05570
CNB:	CNBA5380
LBC:	LACBIDRAFT_319363
MPR:	MPER_10013
CCI:	CC1G_04251
SCM:	SCHCODRAFT_77555
UMA:	UM04151.1
MGL:	MGL_0346
ECU:	ECU06_0200
MBR:	MONBRDRAFT_34274
NGR:	NAEGRDRAFT_80698
DDI:	DDB_G0267414(repD)
EHI:	EHI_132410(297.t00005)
EDI:	EDI_129110
PFA:	PFI1650w
PYO:	PY00738
PKN:	PKH_073220
PVX:	PVX_087010
TAN:	TA19155
TPV:	TP01_0155
BBO:	BBOV_IV001300(21.m02831)
CPV:	cgd7_820
CHO:	Chro.70101
TGO:	TGME49_016870
TET:	TTHERM_00316410
PTM:	GSPATT00036512001
TBR:	Tb927.8.5980(Tb08.11J15.890)
TCR:	511075.30
LMA:	LMJF_24_2280
LIF:	LINJ_24_2370
LDO:	LDBPK_242370
LMI:	LMXM_24_2280
LBZ:	LBRM_24_2360
GLA:	GL50803_4328
TVA:	TVAG_023300 TVAG_442190
PTI:	PHATRDRAFT_54072(ERCC2)
TPS:	THAPSDRAFT_268868(ERCC2)
PIF:	PITG_15696
PPF:	Pput_2850
PPW:	PputW619_2972
MAQ:	Maqu_0015
BPS:	BPSS0856
BPM:	BURPS1710b_A2454
BPL:	BURPS1106A_A1186
BPD:	BURPS668_A1260
BTE:	BTH_II1550
POL:	Bpro_1361
PNA:	Pnap_0984
GUR:	Gura_2112
GEM:	GM21_4133
PPD:	Ppro_1847
CPF:	CPF_1408
CNO:	NT01CX_0936
AMT:	Amet_4220
DHD:	Dhaf_2947
MAC:	MA0335
MBA:	Mbar_A1376
MMA:	MM_1587
MBU:	Mbur_1566
MMH:	Mmah_0134
MEV:	Metev_2209
MZH:	Mzhil_1973
MTP:	Mthe_1672
MHU:	Mhun_0965
MLA:	Mlab_1104
MEM:	Memar_0789
MPI:	Mpet_1921
MBN:	Mboo_1117
MPL:	Mpal_1699
MPD:	MCP_0832
RCI:	RCIX2277(repD)
HAL:	VNG1383G(rad3a) VNG2441G(rad3b)
HSL:	OE2981F(rad3a) OE4424R(rad3b)
HMA:	rrnAC0680(rad3a) rrnAC2719(rad3b)
HWA:	HQ1981A(rad3) HQ3720A(rad3b)
NPH:	NP0960A(rad3a) NP1306A(rad3b)
HLA:	Hlac_0816 Hlac_2627
HUT:	Huta_1416 Huta_2465
HMU:	Hmuk_0823 Hmuk_2975
HTU:	Htur_0335 Htur_3766
NMG:	Nmag_1769 Nmag_1918
HVO:	HVO_0039(rad3b) HVO_1351(rad3a)
HJE:	HacjB3_01015 HacjB3_10045
HBO:	Hbor_01810 Hbor_18810 Hbor_35780
HXA:	Halxa_1367 Halxa_1409
TAC:	Ta0057m(RAD3)
TVO:	TVN0013
PTO:	PTO0884
PHO:	PH0697
PAB:	PAB2385
PFU:	PF0933
TKO:	TK0784
TON:	TON_1040
TGA:	TGAM_0797(rad3)
TSI:	TSIB_1213
TBA:	TERMP_01136
ABI:	Aboo_0196
APE:	APE_0322.1
IHO:	Igni_0053
IAG:	Igag_1007
HBU:	Hbut_0064
PFM:	Pyrfu_0780
SSO:	SSO0313
STO:	ST2280
SAI:	Saci_0192
SIS:	LS215_1929
SIA:	M1425_1789
SIM:	M1627_1907
SID:	M164_1837
SIY:	YG5714_1906
SIN:	YN1551_1019
SII:	LD85_2048
MSE:	Msed_1867
PAI:	PAE2991
PIS:	Pisl_0390
PCL:	Pcal_1117
PAS:	Pars_1357
CMA:	Cmaq_0620
TNE:	Tneu_1737
VDI:	Vdis_2467
TPE:	Tpen_0478 Tpen_1812
KCR:	Kcr_1088

» show all

Reference

PMID:14550632

Authors

Zurita M, Merino C

Title

The transcriptional complexity of the TFIIH complex.

Journal

Trends Genet 19:578-84 (2003)

Reference

PMID:20016270

Authors

Oksenych V, Coin F

Title

The long unwinding road: XPB and XPD helicases in damaged DNA opening.

Journal

Cell Cycle 9:90-6 (2010)

All links

Ontology (7)   
   KEGG BRITE (6)   
   GO (1)   
Pathway (81)   
   KEGG PATHWAY (4)   
   KEGG MODULE (77)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (4217)   
   KEGG GENES (252)   
   KEGG DGENES (14)   
   KEGG EGENES (97)   
   KEGG MGENES (3854)   
Protein sequence (227)   
   UniProt (227)   
Literature (2)   
   PubMed (2)   
All databases (4536)   

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