KEGG   ORTHOLOGY: K10887Help
Entry
K10887                      KO                                     

Name
DCLRE1C, ARTEMIS, SCIDA
Definition
DNA cross-link repair 1C protein [EC:3.1.-.-]
Pathway
Non-homologous end-joining
Primary immunodeficiency
Disease
H00092  
T-B-Severe combined immunodeficiencies (SCIDs)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03450 Non-homologous end-joining
    K10887  DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein
 Human Diseases
  Immune diseases
   05340 Primary immunodeficiency
    K10887  DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.-  Acting on ester bonds
    3.1.-.-  
     K10887  DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    Other NHEJ factors
     K10887  DCLRE1C, ARTEMIS, SCIDA; DNA cross-link repair 1C protein
BRITE hierarchy
Genes
HSA: 
64421(DCLRE1C)
PTR: 
450319(DCLRE1C)
PPS: 
100982138(DCLRE1C)
GGO: 
PON: 
100173437(DCLRE1C)
NLE: 
100579542(DCLRE1C)
MCC: 
697493(DCLRE1C)
MCF: 
102134882(DCLRE1C)
CJC: 
100402124(DCLRE1C)
MMU: 
227525(Dclre1c)
RNO: 
259171(Dclre1c)
CGE: 
100752196(Dclre1c)
HGL: 
101700859(Dclre1c)
TUP: 
102489296(DCLRE1C)
CFA: 
487123(DCLRE1C)
AML: 
100469797(DCLRE1C)
UMR: 
103664190(DCLRE1C)
FCA: 
101089021(DCLRE1C)
PTG: 
102964430(DCLRE1C)
BTA: 
517886(DCLRE1C)
BOM: 
102265039(DCLRE1C)
PHD: 
CHX: 
OAS: 
101108937(DCLRE1C)
SSC: 
100512855(DCLRE1C)
CFR: 
BACU: 
102998143(DCLRE1C)
LVE: 
103084340(DCLRE1C)
ECB: 
100056337(DCLRE1C)
MYB: 
MYD: 
102757426(DCLRE1C)
PALE: 
102898649(DCLRE1C)
MDO: 
100014840(DCLRE1C)
SHR: 
100934017(DCLRE1C)
OAA: 
100085149(DCLRE1C)
GGA: 
430764(DCLRE1C)
MGP: 
APLA: 
101795806(DCLRE1C)
TGU: 
100220075(DCLRE1C)
FAB: 
101816489(DCLRE1C)
PHI: 
102106445(DCLRE1C)
FPG: 
101915924(DCLRE1C)
FCH: 
102059289(DCLRE1C)
CLV: 
102087716(DCLRE1C)
ASN: 
102388511(DCLRE1C)
AMJ: 
PSS: 
102454446(DCLRE1C)
CMY: 
102937269(DCLRE1C)
ACS: 
100553017(dclre1c)
PBI: 
103056873(DCLRE1C)
XTR: 
100493603(dclre1c)
DRE: 
566285(dclre1c)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103190717(dclre1c)
BFO: 
CIN: 
SPU: 
AGA: 
CQU: 
AME: 
726638(GB15982)
NVI: 
TCA: 
BMOR: 
API: 
ISC: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
NVE: 
TAD: 
AQU: 
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yan Y, Akhter S, Zhang X, Legerski R
  Title
The multifunctional SNM1 gene family: not just nucleases.
  Journal
Future Oncol 6:1015-29 (2010)
  Sequence
[hsa:64421]
Reference
  Authors
Ma Y, Schwarz K, Lieber MR
  Title
The Artemis:DNA-PKcs endonuclease cleaves DNA loops, flaps, and gaps.
  Journal
DNA Repair (Amst) 4:845-51 (2005)
  Sequence
[hsa:64421]

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