KEGG   ORTHOLOGY: K10956Help
Entry
K10956                      KO                                     

Name
SEC61A
Definition
protein transport protein SEC61 subunit alpha
Pathway
ko03060  Protein export
ko04141  Protein processing in endoplasmic reticulum
ko04145  Phagosome
ko05110  Vibrio cholerae infection
Module
M00401  Sec61 complex
Disease
H00541  Autosomal dominant tubulointerstitial kidney disease (ADTKD)
H02011  Familial juvenile hyperuricemic nephropathy (HNFJ)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   03060 Protein export
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
   04141 Protein processing in endoplasmic reticulum
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
 Human Diseases
  Infectious diseases
   05110 Vibrio cholerae infection
    K10956  SEC61A; protein transport protein SEC61 subunit alpha
KEGG modules [BR:ko00002]
 Structural complex
  Genetic information processing
   Protein processing
    M00401  Sec61 complex
     K10956  SEC61A; protein transport protein SEC61 subunit alpha
Secretion system [BR:ko02044]
 Sec (secretion) system
  Eukaryotic Sec-SRP protein
   K10956  SEC61A; protein transport protein SEC61 subunit alpha
BRITE hierarchy
Other DBs
TC: 3.A.5.4 3.A.5.8 3.A.5.9
Genes
HSA: 29927(SEC61A1) 55176(SEC61A2)
PTR: 450305(SEC61A2) 460669(SEC61A1)
PPS: 100979100(SEC61A2) 100979567(SEC61A1)
GGO: 101145654(SEC61A1) 101147036(SEC61A2) 109026253
PON: 100173741(SEC61A1) 100174115(SEC61A2)
NLE: 100599187(SEC61A2) 100603743(SEC61A1)
MCC: 100427731(SEC61A2) 709787(SEC61A1)
MCF: 102116756(SEC61A1) 102119298(SEC61A2)
CSAB: 103228100(SEC61A1) 103237891
RRO: 104656940(SEC61A1) 104664883(SEC61A2)
RBB: 108519219 108525150 108537478(SEC61A1) 108538528(SEC61A2)
CJC: 100413259(SEC61A1) 100415365(SEC61A2)
SBQ: 101038739(SEC61A1) 101041434(SEC61A2)
MMU: 53421(Sec61a1) 57743(Sec61a2)
RNO: 361273(Sec61a2) 80843(Sec61a1)
CGE: 100767375(Sec61a1) 100771837(Sec61a2)
NGI: 103730347(Sec61a1) 103738699(Sec61a2)
HGL: 101711449(Sec61a1) 101724032(Sec61a2)
CCAN: 109682444(Sec61a2) 109684702(Sec61a1)
OCU: 100338258(SEC61A2) 100338900(SEC61A1)
TUP: 102480124(SEC61A2) 102490355(SEC61A1)
CFA: 404006(SEC61A1) 478007(SEC61A2)
AML: 100478647(SEC61A1) 100484123(SEC61A2)
UMR: 103669615(SEC61A1) 103676291(SEC61A2)
ORO: 101363735(SEC61A2) 101365069(SEC61A1)
FCA: 101086402(SEC61A2) 101089426(SEC61A1)
PTG: 102955516(SEC61A2) 102966531(SEC61A1)
AJU: 106971003(SEC61A2) 106986127(SEC61A1)
BTA: 505064(SEC61A1) 614128(SEC61A2)
BOM: 102264991(SEC61A1) 102283876(SEC61A2)
BIU: 109567871(SEC61A2) 109576222(SEC61A1)
PHD: 102329110(SEC61A1) 102331927(SEC61A2)
CHX: 102173946(SEC61A2) 102175814(SEC61A1)
OAS: 101108676(SEC61A2) 101114060(SEC61A1)
SSC: 100155306(SEC61A1) 100511831(SEC61A2)
CFR: 102505665(SEC61A2) 102523145(SEC61A1)
CDK: 105090114(SEC61A1) 105100311(SEC61A2)
BACU: 103012399(SEC61A1) 103015508(SEC61A2)
LVE: 103079854 103086204(SEC61A1) 103088812(SEC61A2)
OOR: 101271372(SEC61A2) 101275317 101281798 101284382(SEC61A1)
ECB: 100054080(SEC61A1) 100069336(SEC61A2)
EPZ: 103558629(SEC61A1) 103563360(SEC61A2)
EAI: 106834472(SEC61A1) 106836525(SEC61A2)
MYB: 102243493(SEC61A2) 102253190(SEC61A1)
MYD: 102755050(SEC61A2) 102770957(SEC61A1)
HAI: 109390484(SEC61A2) 109391269(SEC61A1)
RSS: 109433765(SEC61A2) 109438672(SEC61A1) 109440815 109441191
PALE: 102895305(SEC61A2) 102896092(SEC61A1)
LAV: 100653932(SEC61A2) 100672139(SEC61A1)
MDO: 100013623(SEC61A2) 100027900(SEC61A1)
SHR: 100926239(SEC61A2) 100927239(SEC61A1)
OAA: 100075168(SEC61A1) 100085428(SEC61A2)
GGA: 416023(SEC61A1) 426369(SEC61A2)
MGP: 100538490(SEC61A1) 100540625(SEC61A2)
CJO: 107317364(SEC61A2) 107319981(SEC61A1)
APLA: 101793156(SEC61A2) 101805438(SEC61A1)
ACYG: 106038064(SEC61A1) 106046212(SEC61A2)
TGU: 100222701 100230635(SEC61A2) 100232642(SEC61A1)
GFR: 102043686(SEC61A1) 102045195(SEC61A2)
FAB: 101810680(SEC61A1) 101819921(SEC61A2)
PHI: 102101105(SEC61A2) 102110505(SEC61A1)
PMAJ: 107204634(SEC61A2) 107210406(SEC61A1)
CCW: 104683473(SEC61A1) 104694503(SEC61A2)
FPG: 101912538(SEC61A1) 101914707(SEC61A2)
FCH: 102046030(SEC61A2) 102057607(SEC61A1)
CLV: 102086241(SEC61A2) 102093863(SEC61A1)
EGZ: 104126631(SEC61A1) 104135762(SEC61A2)
AAM: 106485094(SEC61A2) 106500278(SEC61A1)
ASN: 102373630(SEC61A2) 102381045(SEC61A1)
AMJ: 102561868(SEC61A2) 106736938(SEC61A1)
PSS: 102458682(SEC61A1) 102460252(SEC61A2)
CMY: 102941548(SEC61A2) 102943934(SEC61A1)
CPIC: 101938621(SEC61A1) 101939960(SEC61A2)
ACS: 100567770(sec61a1)
PVT: 110081240(SEC61A2) 110088891(SEC61A1)
PBI: 103048227(SEC61A1) 103051548 103065081(SEC61A2)
GJA: 107122943(SEC61A1)
XLA: 108714662(sec61a1.L) 379936(sec61a1.S)
XTR: 448033(sec61a1)
NPR: 108784976(SEC61A1)
DRE: 192298(sec61a1) 266796(sec61a1l)
TRU: 101061140(sec61a1) 101075256
OLA: 101169601 101175640(sec61a1)
CSEM: 103386165(sec61a1)
SASA: 100195187(s61a1) 100380825(sc61a) 106565561 106583199
LCM: 102358133(SEC61A1) 102359033(SEC61A2)
CMK: 103176668(sec61a1) 103187913(sec61a2)
CIN: 100176997
SPU: 576070
APLC: 110987733
DME: Dmel_CG9539(Sec61alpha)
DSI: Dsimw501_GD22572(Dsim_GD22572)
MDE: 101890594
AME: 725571(Sec61alpha)
BIM: 100747066
BTER: 100644740
SOC: 105207861
AEC: 105154433
ACEP: 105621039
PBAR: 105428379
HST: 105191762
CFO: 105252208
LHU: 105669772
PGC: 109856141
NVI: 100114093 100114600(Sec61alpha)
TCA: 658693
DPA: 109545449
NVL: 108569651
BMOR: 733068(Sec61alpha)
PMAC: 106721338
PRAP: 110993494
API: 100144911(Sec61a1)
DNX: 107173078
ZNE: 110836545
FCD: 110846340
TUT: 107364556
CEL: CELE_Y57G11C.15(sec-61)
CBR: CBG21508
BMY: Bm1_38585
MYI: 110445924
OBI: 106872762
SHX: MS3_03569
EPA: 110240522
ADF: 107337419
HMG: 100200475
AQU: 100635757
LJA: Lj4g3v0880270.1(Lj4g3v0880270.1)
FVE: 101311165
DOSA: Os03t0213100-01(Os03g0213100) Os03t0692300-00(Os03g0692300) Os08t0254500-01(Os08g0254500) Os09t0347500-01(Os09g0347500) Os09t0347700-01(Os09g0347700) Os09t0512000-01(Os09g0512000) Os12t0612625-00(Os12g0612625)
ATS: 109731640(LOC109731640) 109741620(LOC109741620) 109764831(LOC109764831) 109764834(LOC109764834) 109770287(LOC109770287)
ZMA: 100217058 100276798 100280289(pco109407) 542482(csy1)
ATR: 18442675
CRE: CHLREDRAFT_188207(SEC61A)
MIS: MICPUN_95488(SEC61a)
APRO: F751_5694
SCE: YBR283C(SSH1) YLR378C(SEC61)
KMX: KLMA_20424(SEC61) KLMA_50087(SSH1)
NCS: NCAS_0B07560(NCAS0B07560) NCAS_0J01340(NCAS0J01340)
NDI: NDAI_0B04900(NDAI0B04900) NDAI_0J02130(NDAI0J02130)
TPF: TPHA_0B02340(TPHA0B02340) TPHA_0I01160(TPHA0I01160)
TBL: TBLA_0C02600(TBLA0C02600) TBLA_0I02820(TBLA0I02820)
TDL: TDEL_0D01700(TDEL0D01700) TDEL_0E01420(TDEL0E01420)
KAF: KAFR_0A03640(KAFR0A03640) KAFR_0A06090(KAFR0A06090)
PIC: PICST_68832(SEC61) PICST_80530(SSH1)
SLB: AWJ20_1740(SEC61) AWJ20_2263(SEC61)
NCR: NCU08897
NTE: NEUTE1DRAFT116142(NEUTE1DRAFT_116142)
MGR: MGG_04856
MAW: MAC_07314
MAJ: MAA_09744
CMT: CCM_09589
MBE: MBM_08204
ANI: AN7721.2
ANG: ANI_1_512034(An03g04340)
ABE: ARB_06748
TVE: TRV_03333
PTE: PTT_09674
CNE: CNI00040
CNB: CNBH0050
MRR: Moror_6
ABP: AGABI1DRAFT114587(AGABI1DRAFT_114587)
ABV: AGABI2DRAFT194769(AGABI2DRAFT_194769)
MGL: MGL_1638
DDI: DDB_G0278885(sec61a)
DFA: DFA_08267(sec61a)
EHI: EHI_164500(467.t00007)
PYO: PY17X_1364700(PY02510)
PCB: PCHAS_136360(PC302415.00.0)
TAN: TA17425
TPV: TP03_0852
BBO: BBOV_I000080(16.m00785)
CPV: cgd7_950
SMIN: v1.2.009289.t1(symbB.v1.2.009289.t1) v1.2.009606.t1(symbB.v1.2.009606.t1) v1.2.022287.t1(symbB.v1.2.022287.t1)
PTI: PHATRDRAFT_56443(Sec61alpha)
TPS: THAPSDRAFT_28769(SEC61-2) THAPS_25355(SEC61-1)
NVN: NVIE_013880(secY)
BARC: AOA65_0151
BARB: AOA66_1261
LOKI: Lokiarch_00020(secY)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
Reference
  Authors
Jiang Y, Cheng Z, Mandon EC, Gilmore R
  Title
An interaction between the SRP receptor and the translocon is critical during cotranslational protein translocation.
  Journal
J Cell Biol 180:1149-61 (2008)
DOI:10.1083/jcb.200707196
  Sequence
Reference
  Authors
Lang S, Erdmann F, Jung M, Wagner R, Cavalie A, Zimmermann R
  Title
Sec61 complexes form ubiquitous ER Ca2+ leak channels.
  Journal
Channels (Austin) 5:228-35 (2011)
DOI:10.4161/chan.5.3.15314
  Sequence
[hsa:29927]

DBGET integrated database retrieval system