KEGG   ORTHOLOGY: K10980Help
Entry
K10980                      KO                                     
Name
NHEJ1, XLF
Definition
non-homologous end-joining factor 1
Pathway
Non-homologous end-joining
Disease
H00924  
Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Replication and repair
   03450 Non-homologous end-joining
    K10980  NHEJ1, XLF; non-homologous end-joining factor 1
DNA repair and recombination proteins [BR:ko03400]
 Eukaryotic Type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    DNA Ligase 4 complex
     K10980  NHEJ1, XLF; non-homologous end-joining factor 1
BRITE hierarchy
Genes
HSA: 
79840(NHEJ1)
PTR: 
742646(NHEJ1)
PPS: 
100992313(NHEJ1)
GGO: 
101140591(NHEJ1)
PON: 
100447888(NHEJ1)
MCC: 
701542(NHEJ1)
MMU: 
75570(Nhej1)
RNO: 
363251(Nhej1)
CFA: 
610570(NHEJ1)
AML: 
FCA: 
101092956(NHEJ1)
BTA: 
509157(NHEJ1)
SSC: 
100153546(NHEJ1)
ECB: 
100056056
MDO: 
100010576
SHR: 
100916985(NHEJ1)
GGA: 
424205(NHEJ1)
TGU: 
100224673(NHEJ1)
ACS: 
100565479
XTR: 
100145147(nhej1)
DRE: 
406593(nhej1)
TRU: 
101061346
OLA: 
101169915
BFO: 
BRAFLDRAFT_84970
SPU: 
754820
TCA: 
662288
NVE: 
NEMVE_v1g203830
HMG: 
100212411
TAD: 
TRIADDRAFT_53808
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tsai CJ, Kim SA, Chu G
  Title
Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends.
  Journal
Proc Natl Acad Sci U S A 104:7851-6 (2007)
DBGET integrated database retrieval system