KEGG   ORTHOLOGY: K11220Help
Entry
K11220                      KO                                     

Name
STAT1
Definition
signal transducer and activator of transcription 1
Pathway
Chemokine signaling pathway
Necroptosis
Osteoclast differentiation
Toll-like receptor signaling pathway
NOD-like receptor signaling pathway
Jak-STAT signaling pathway
Th1 and Th2 cell differentiation
Th17 cell differentiation
Prolactin signaling pathway
Thyroid hormone signaling pathway
AGE-RAGE signaling pathway in diabetic complications
Leishmaniasis
Toxoplasmosis
Tuberculosis
Hepatitis C
Hepatitis B
Measles
Influenza A
Human papillomavirus infection
Kaposi's sarcoma-associated herpesvirus infection
Herpes simplex infection
Pathways in cancer
Pancreatic cancer
Inflammatory bowel disease (IBD)
Module
M00684  
JAK-STAT signaling
Disease
H00089  
IFN-gamma/IL-12 axis
H00363  
Candidiasis
H01109  
Chronic mucocutaneous candidiasis (CMC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
 Cellular Processes
  Cell growth and death
   04217 Necroptosis
    K11220  STAT1; signal transducer and activator of transcription 1
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04621 NOD-like receptor signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04658 Th1 and Th2 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04659 Th17 cell differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
   04062 Chemokine signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  Endocrine system
   04917 Prolactin signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
   04919 Thyroid hormone signaling pathway
    K11220  STAT1; signal transducer and activator of transcription 1
  Development
   04380 Osteoclast differentiation
    K11220  STAT1; signal transducer and activator of transcription 1
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K11220  STAT1; signal transducer and activator of transcription 1
   05212 Pancreatic cancer
    K11220  STAT1; signal transducer and activator of transcription 1
  Immune diseases
   05321 Inflammatiory bowel disease (IBD)
    K11220  STAT1; signal transducer and activator of transcription 1
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K11220  STAT1; signal transducer and activator of transcription 1
  Infectious diseases
   05152 Tuberculosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05162 Measles
    K11220  STAT1; signal transducer and activator of transcription 1
   05164 Influenza A
    K11220  STAT1; signal transducer and activator of transcription 1
   05161 Hepatitis B
    K11220  STAT1; signal transducer and activator of transcription 1
   05160 Hepatitis C
    K11220  STAT1; signal transducer and activator of transcription 1
   05168 Herpes simplex infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05165 Human papillomavirus infection
    K11220  STAT1; signal transducer and activator of transcription 1
   05145 Toxoplasmosis
    K11220  STAT1; signal transducer and activator of transcription 1
   05140 Leishmaniasis
    K11220  STAT1; signal transducer and activator of transcription 1
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00684  JAK-STAT signaling
     K11220  STAT1; signal transducer and activator of transcription 1
Transcription factors [BR:ko03000]
 Eukaryotic Type
  beta-Scaffold factors with minor groove contacts
   STAT
    K11220  STAT1; signal transducer and activator of transcription 1
BRITE hierarchy
Genes
HSA: 
6772(STAT1)
PTR: 
459834(STAT1)
PPS: 
100971620(STAT1)
GGO: 
101131770(STAT1)
PON: 
100173683(STAT1)
NLE: 
100596344(STAT1)
MCC: 
693650(STAT1)
MCF: 
101925134(STAT1)
CSAB: 
103217529(STAT1)
RRO: 
104675282(STAT1)
RBB: 
108527866(STAT1)
CJC: 
100401630(STAT1)
SBQ: 
101030811(STAT1)
MMU: 
20846(Stat1)
RNO: 
25124(Stat1)
CGE: 
100755609(Stat1)
NGI: 
103736156(Stat1)
HGL: 
101718902(Stat1)
CCAN: 
OCU: 
100343893(STAT1)
TUP: 
102476590(STAT1)
CFA: 
488449(STAT1)
AML: 
100474026(STAT1)
UMR: 
103659933(STAT1)
ORO: 
101378785(STAT1)
FCA: 
101084561(STAT1)
PTG: 
102953174(STAT1)
AJU: 
106979712(STAT1)
BTA: 
510814(STAT1)
BOM: 
102283508(STAT1)
BIU: 
109568771(STAT1)
PHD: 
CHX: 
102189170(STAT1)
OAS: 
100307049(STAT1)
SSC: 
396655(STAT1)
CFR: 
102509999(STAT1)
CDK: 
105088783(STAT1)
BACU: 
LVE: 
ECB: 
100069633(STAT1)
EPZ: 
103548655(STAT1)
EAI: 
106828796(STAT1)
MYB: 
102243651(STAT1)
MYD: 
102757059(STAT1)
HAI: 
109393276(STAT1)
RSS: 
109452057(STAT1)
PALE: 
102886603(STAT1)
LAV: 
100668424(STAT1)
TMU: 
MDO: 
100028917(STAT1)
SHR: 
105749862(STAT1)
OAA: 
GGA: 
424044(STAT1)
MGP: 
100544816(STAT1)
CJO: 
107316322(STAT1)
APLA: 
ACYG: 
106039967(STAT1)
TGU: 
100221342(STAT1)
GFR: 
102036007(STAT1)
FAB: 
101811260(STAT1)
PHI: 
102100816(STAT1)
PMAJ: 
107207405(STAT1)
CCW: 
104693738(STAT1)
FPG: 
101922205(STAT1)
FCH: 
102054689(STAT1)
CLV: 
102098106(STAT1)
EGZ: 
104130544(STAT1)
AAM: 
106492439(STAT1)
ASN: 
102374439(STAT1)
AMJ: 
102571738(STAT1)
PSS: 
102462741(STAT1)
CMY: 
CPIC: 
101931440(STAT1)
ACS: 
100558595(stat1)
PVT: 
110083952(STAT1)
PBI: 
103060112(STAT1)
XLA: 
108703082 398324(stat1.L)
XTR: 
780397(stat1)
NPR: 
108798858(STAT1)
DRE: 
30768(stat1a) 368481(stat1b)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
AMEX: 
TRU: 
TNG: 
LCO: 
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
NFU: 
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102353760(STAT1) 102355078(STAT2)
CMK: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1502203
  Authors
Schindler C, Fu XY, Improta T, Aebersold R, Darnell JE Jr
  Title
Proteins of transcription factor ISGF-3: one gene encodes the 91-and 84-kDa ISGF-3 proteins that are activated by interferon alpha.
  Journal
Proc Natl Acad Sci U S A 89:7836-9 (1992)
DOI:10.1073/pnas.89.16.7836
  Sequence
[hsa:6772]

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