KEGG   ORTHOLOGY: K11421Help
Entry
K11421                      KO                                     

Name
SETDB
Definition
histone-lysine N-methyltransferase SETDB [EC:2.1.1.43]
Pathway
Lysine degradation
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K11421  SETDB; histone-lysine N-methyltransferase SETDB
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K11421  SETDB; histone-lysine N-methyltransferase SETDB
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K11421  SETDB; histone-lysine N-methyltransferase SETDB
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    K11421  SETDB; histone-lysine N-methyltransferase SETDB
BRITE hierarchy
Other DBs
Genes
HSA: 
83852(SETDB2) 9869(SETDB1)
PTR: 
452719(SETDB2) 469481(SETDB1)
PPS: 
100972839(SETDB1) 100986951(SETDB2)
GGO: 
101141713(SETDB2) 101146215(SETDB1)
PON: 
MCC: 
706277(SETDB2) 716141(SETDB1)
MCF: 
102117410(SETDB1) 102124788(SETDB2)
MMU: 
239122(Setdb2) 84505(Setdb1)
RNO: 
100361710(Setdb2) 689883(Setdb1)
CGE: 
HGL: 
101696702(Setdb2) 101715248(Setdb1)
TUP: 
102502264(SETDB1) 102503290(SETDB2)
CFA: 
483186(SETDB1) 485441(SETDB2)
AML: 
100476962(SETDB2) 100482250(SETDB1)
FCA: 
101094118(SETDB1) 101100356(SETDB2)
BTA: 
100138100(SETDB1) 509382(SETDB2)
BOM: 
102287560(SETDB2) 102288279(SETDB1)
PHD: 
102329173(SETDB1) 102343350(SETDB2)
CHX: 
102180982(SETDB1) 102186776(SETDB2)
SSC: 
100157885(SETDB2) 100157920(SETDB1)
CFR: 
102512057(SETDB1) 102514903(SETDB2)
ECB: 
100056120(SETDB2) 100059254(SETDB1)
MYB: 
102248401(SETDB2) 102257713(SETDB1)
MDO: 
SHR: 
100928904(SETDB1) 100934863(SETDB2)
OAA: 
100083315(SETDB2)
GGA: 
101751150 395847(SETDB1) 418866(SETDB2)
MGP: 
TGU: 
100231131(SETDB2) 100231651(SETDB1)
FAB: 
101812936(SETDB2)
PHI: 
102101563(SETDB1) 102104074(SETDB2)
APLA: 
101790074(SETDB2) 101794756(SETDB1)
FPG: 
101912073(SETDB1) 101917763(SETDB2)
FCH: 
102055212(SETDB1) 102055395(SETDB2)
CLV: 
102088543(SETDB2) 102094505(SETDB1)
ASN: 
102380189(SETDB2) 102382539(SETDB1)
PSS: 
102446148(SETDB1) 102450951(SETDB2)
ACS: 
XLA: 
398711(setdb2) 432147(setdb1)
XTR: 
100124743(setdb2) 100490309(setdb1)
DRE: 
335153(setdb2) 768131(setdb1b)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102356699(SETDB1) 102363588(SETDB2)
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
409098(egg)
NVI: 
100120014(Setdb1)
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CBR: 
CBG18157(Cbr-met-2)
BMY: 
LOA: 
SMM: 
HMG: 
TAD: 
ACAN: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn MY, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, Kato S
  Title
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.
  Journal
Nat Cell Biol 9:1273-85 (2007)
Reference
  Authors
Falandry C, Fourel G, Galy V, Ristriani T, Horard B, Bensimon E, Salles G, Gilson E, Magdinier F
  Title
CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation.
  Journal
J Biol Chem 285:20234-41 (2010)

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