KEGG   ORTHOLOGY: K11421Help
Entry
K11421                      KO                                     

Name
SETDB1
Definition
histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43]
Pathway
ko00310  Lysine degradation
ko04550  Signaling pathways regulating pluripotency of stem cells
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00310 Lysine degradation
    K11421  SETDB1; histone-lysine N-methyltransferase SETDB1
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K11421  SETDB1; histone-lysine N-methyltransferase SETDB1
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.43  histone-lysine N-methyltransferase
     K11421  SETDB1; histone-lysine N-methyltransferase SETDB1
Chromosome [BR:ko03036]
 Eukaryotic Type
  Histone modification proteins
   HMTs (histone methyltransferases)
    HKMTs (histone lysine methyltransferases)
     K11421  SETDB1; histone-lysine N-methyltransferase SETDB1
  Heterochromatin formation proteins
   Other heterochromatin formation proteins
    K11421  SETDB1; histone-lysine N-methyltransferase SETDB1
BRITE hierarchy
Other DBs
RN: R03875 R03938 R04866 R04867
GO: 0018024
Genes
HSA: 9869(SETDB1)
PTR: 469481(SETDB1)
PPS: 100972839(SETDB1)
GGO: 101146215(SETDB1)
NLE: 100581330(SETDB1)
MCC: 716141(SETDB1)
MCF: 102117410(SETDB1)
CSAB: 103247223(SETDB1)
RRO: 104681064(SETDB1)
RBB: 108533259(SETDB1)
CJC: 100411734(SETDB1)
SBQ: 101042658(SETDB1)
MMU: 84505(Setdb1)
RNO: 689883(Setdb1)
CGE: 100765697(Setdb1) 107979496
NGI: 103730089(Setdb1)
HGL: 101715248(Setdb1)
CCAN: 109681205(Setdb1)
OCU: 100355877(SETDB1)
TUP: 102502264(SETDB1)
CFA: 483186(SETDB1)
AML: 100482250(SETDB1)
UMR: 103667532(SETDB1)
ORO: 101372094(SETDB1)
FCA: 101094118(SETDB1)
PTG: 102970727(SETDB1)
AJU: 106979835(SETDB1)
BTA: 100138100(SETDB1)
BOM: 102288279(SETDB1)
BIU: 109555305(SETDB1)
PHD: 102329173(SETDB1)
CHX: 102180982(SETDB1)
OAS: 101109230(SETDB1)
SSC: 100157920(SETDB1)
CFR: 102512057(SETDB1)
CDK: 105103196(SETDB1)
BACU: 103009894(SETDB1)
LVE: 103076461(SETDB1)
OOR: 101270688(SETDB1)
ECB: 100059254(SETDB1)
EPZ: 103547642(SETDB1)
EAI: 106846522(SETDB1)
MYB: 102257713(SETDB1)
MYD: 102773684(SETDB1)
HAI: 109372277(SETDB1)
RSS: 109451617(SETDB1)
PALE: 102886191(SETDB1)
LAV: 100673374(SETDB1)
TMU: 101349341
MDO: 100618580(SETDB1)
SHR: 100928904(SETDB1)
OAA: 100091318
GGA: 100859816(SETDB1) 395847(MLLT11)
MGP: 100542346(SETDB1)
CJO: 107324577(SETDB1)
APLA: 101794756(SETDB1)
ACYG: 106049268(SETDB1)
TGU: 100231651(SETDB1)
GFR: 102034546(SETDB1)
PHI: 102101563(SETDB1)
PMAJ: 107214655(SETDB1)
FPG: 101912073(SETDB1)
FCH: 102055212(SETDB1)
CLV: 102094505(SETDB1)
EGZ: 104129700(SETDB1)
AAM: 106495416(SETDB1)
ASN: 102382539(SETDB1)
AMJ: 102575637(SETDB1)
PSS: 102446148 102448836(SETDB1)
CMY: 102937828(SETDB1)
CPIC: 101931963(SETDB1)
ACS: 100565799(setdb1)
PVT: 110081479(SETDB1)
PBI: 103053131(SETDB1)
GJA: 107121584(SETDB1)
XLA: 108700333(setdb1.S) 432147(setdb1.L)
XTR: 100490309(setdb1)
NPR: 108789810(SETDB1)
DRE: 553292(setdb1a) 768131(setdb1b)
IPU: 108266106(setdb1) 108272679
AMEX: 103027968(setdb1) 103028156
TRU: 101063516 101075200(setdb1)
LCO: 104920543(setdb1)
NCC: 104944919(setdb1)
MZE: 101465322(setdb1) 101485997
PRET: 103472675 103478723(setdb1)
CSEM: 103388279(setdb1) 103394578
HCQ: 109522778(setdb1)
BPEC: 110163046(setdb1) 110167468
SFM: 108923796(setdb1)
LCM: 102356699(SETDB1) 106705364
CIN: 101242243
SPU: 764341
APLC: 110986848
SKO: 100372058
DME: Dmel_CG12196(egg)
DSI: Dsimw501_GD24920(Dsim_GD24920)
MDE: 101893339
AME: 409098(egg)
BIM: 100745488
BTER: 100647514
SOC: 105201335
AEC: 105144993
ACEP: 105620791
PBAR: 105429250
HST: 105186113
CFO: 105256000
LHU: 105670399
PGC: 109857860
NVI: 100120014(Setdb1)
TCA: 658295
DPA: 109543261
NVL: 108566549
BMOR: 101742950
PMAC: 106721248
PRAP: 110997400
ZNE: 110837361
CEL: CELE_R05D3.11(met-2)
CBR: CBG18157(Cbr-met-2)
BMY: Bm1_19995
CRG: 105332598
MYI: 110459908
OBI: 106873585
SHX: MS3_06263
EPA: 110238173
ADF: 107337481
HMG: 100203637
AQU: 109582610
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Takada I, Mihara M, Suzawa M, Ohtake F, Kobayashi S, Igarashi M, Youn MY, Takeyama K, Nakamura T, Mezaki Y, Takezawa S, Yogiashi Y, Kitagawa H, Yamada G, Takada S, Minami Y, Shibuya H, Matsumoto K, Kato S
  Title
A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation.
  Journal
Nat Cell Biol 9:1273-85 (2007)
DOI:10.1038/ncb1647
  Sequence
[hsa:9869]

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