KEGG   ORTHOLOGY: K11480Help
Entry
K11480                      KO                                     
Name
AURKC
Definition
aurora kinase C [EC:2.7.11.1]
Disease
H01282  
Spermatogenic failure
Brite
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K11480  AURKC; aurora kinase C
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Others
  Aur family
   K11480  AURKC; aurora kinase C
Chromosome [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     K11480  AURKC; aurora kinase C
  Sister chromatid separation proteins
   Aurora kinases
    K11480  AURKC; aurora kinase C
BRITE hierarchy
Genes
HSA: 
6795(AURKC)
PTR: 
740217(AURKC)
PPS: 
100990499(AURKC)
GGO: 
101137002(AURKC)
PON: 
100452550(AURKC)
MCC: 
709801(AURKC)
MMU: 
20871(Aurkc)
RNO: 
292554(Aurkc)
BTA: 
618599(AURKC)
ECB: 
TaxonomyKoalaUniProt
Reference
  Authors
Tang CJ, Lin CY, Tang TK
  Title
Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.
  Journal
Dev Biol 290:398-410 (2006)
Reference
  Authors
Dieterich K, Soto Rifo R, Faure AK, Hennebicq S, Ben Amar B, Zahi M, Perrin J, Martinez D, Sele B, Jouk PS, Ohlmann T, Rousseaux S, Lunardi J, Ray PF
  Title
Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.
  Journal
Nat Genet 39:661-5 (2007)
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