KEGG   ORTHOLOGY: K11480Help
Entry
K11480                      KO                                     

Name
AURKC
Definition
aurora kinase C [EC:2.7.11.1]
Disease
H01282  Spermatogenic failure
Brite
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K11480  AURKC; aurora kinase C
Protein kinases [BR:ko01001]
 Serine/threonine kinases: AGC group
  AUR family [OT]
   K11480  AURKC; aurora kinase C
Chromosome and associated proteins [BR:ko03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     K11480  AURKC; aurora kinase C
  Sister chromatid separation proteins
   Aurora kinases
    K11480  AURKC; aurora kinase C
BRITE hierarchy
Genes
HSA: 6795(AURKC)
PTR: 740217(AURKC)
PPS: 100990499(AURKC)
GGO: 101137002(AURKC)
PON: 100452550(AURKC)
NLE: 100590820(AURKC)
MCC: 709801(AURKC)
MCF: 102133523(AURKC)
CSAB: 103235385(AURKC)
RRO: 104680920(AURKC)
RBB: 108537761(AURKC)
CJC: 100412349(AURKC)
SBQ: 101033581(AURKC)
MMU: 20871(Aurkc) 637541(Gm7207)
RNO: 292554(Aurkc)
CGE: 100762186(Aurkc)
NGI: 103752346(Aurkc)
HGL: 101716027(Aurkc)
CCAN: 109690666
OCU: 100343856(AURKC)
TUP: 106733663(AURKC)
CFA: 102155400(AURKC)
AML: 105239983(AURKC)
UMR: 103677270(AURKC)
ORO: 101362262(AURKC)
FCA: 101096595 102899963(AURKC)
PTG: 102971466(AURKC)
AJU: 106985880(AURKC)
BTA: 101903509 618599(AURKC)
BOM: 102267065 102273854(AURKC)
BIU: 109571788 109572316(AURKC)
PHD: 102340734(AURKC)
CHX: 102172930(AURKC)
OAS: 101104774(AURKC) 101116758
SSC: 110261315
CFR: 102507337(AURKC)
CDK: 105084472(AURKC)
BACU: 103017075(AURKC)
LVE: 103080405(AURKC)
OOR: 101288451(AURKC)
ECB: 100051177(AURKC)
EPZ: 103543884(AURKC)
EAI: 106847402(AURKC)
MYB: 102260085 102263776(AURKC)
MYD: 102770424(AURKC)
HAI: 109376674(AURKC)
RSS: 109437587(AURKC)
PALE: 102879177(AURKC)
LAV: 100660262(AURKC)
TMU: 111822433
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Tang CJ, Lin CY, Tang TK
  Title
Dynamic localization and functional implications of Aurora-C kinase during male mouse meiosis.
  Journal
Dev Biol 290:398-410 (2006)
DOI:10.1016/j.ydbio.2005.11.036
  Sequence
[mmu:20871]
Reference
  Authors
Dieterich K, Soto Rifo R, Faure AK, Hennebicq S, Ben Amar B, Zahi M, Perrin J, Martinez D, Sele B, Jouk PS, Ohlmann T, Rousseaux S, Lunardi J, Ray PF
  Title
Homozygous mutation of AURKC yields large-headed polyploid spermatozoa and causes male infertility.
  Journal
Nat Genet 39:661-5 (2007)
DOI:10.1038/ng2027
  Sequence
[hsa:6795]
Reference
  Authors
Li X, Sakashita G, Matsuzaki H, Sugimoto K, Kimura K, Hanaoka F, Taniguchi H, Furukawa K, Urano T
  Title
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C.
  Journal
J Biol Chem 279:47201-11 (2004)
DOI:10.1074/jbc.M403029200
  Sequence
[hsa:6795]

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