KEGG   ORTHOLOGY: K11988Help
Entry
K11988                      KO                                     
Name
SHH
Definition
sonic hedgehog
Pathway
Hedgehog signaling pathway
Pathways in cancer
Basal cell carcinoma
Disease
H00039  
Basal cell carcinoma
H00267  
Holoprosencephaly (HPE)
H00652  
Solitary median maxillary central incisor syndrome
H01027  
Anophthalmia and microphthalmia (A/M)
H01160  
Schizencephaly
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04340 Hedgehog signaling pathway
    K11988  SHH; sonic hedgehog
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K11988  SHH; sonic hedgehog
   05217 Basal cell carcinoma
    K11988  SHH; sonic hedgehog
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C46: hedgehog family
   K11988  SHH; sonic hedgehog
Heparan sulfate/heparin binding proteins [BR:ko00536]
 Morphogens
  K11988  SHH; sonic hedgehog
BRITE hierarchy
Genes
HSA: 
6469(SHH)
PTR: 
743371(SHH)
PPS: 
GGO: 
PON: 
MCC: 
716553(SHH)
MMU: 
20423(Shh)
RNO: 
29499(Shh)
CFA: 
608860(SHH)
AML: 
BTA: 
286821(SHH)
SSC: 
100512749(SHH)
ECB: 
100147450
MDO: 
100016531(SHH)
SHR: 
100925029(SHH)
GGA: 
395615(SHH)
MGP: 
100546709
TGU: 
100222391(SHH)
ACS: 
100557233
XLA: 
398047(shh)
DRE: 
30269(shha) 30444(shhb)
TRU: 
446055(shh)
OLA: 
100049186(shh)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7583126
  Authors
Lopez-Martinez A, Chang DT, Chiang C, Porter JA, Ros MA, Simandl BK, Beachy PA, Fallon JF
  Title
Limb-patterning activity and restricted posterior localization of the amino-terminal product of Sonic hedgehog cleavage.
  Journal
Curr Biol 5:791-6 (1995)
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