KEGG   ORTHOLOGY: K12077Help
Entry
K12077                      KO                                     
Name
PDK1
Definition
pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]
Pathway
HIF-1 signaling pathway
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Neurotrophin signaling pathway
Toxoplasmosis
Hepatitis C
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
   04664 Fc epsilon RI signaling pathway
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
  Nervous system
   04722 Neurotrophin signaling pathway
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
  Infectious diseases
   05160 Hepatitis C
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
   05145 Toxoplasmosis
    K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.2  [pyruvate dehydrogenase (acetyl-transferring)] kinase
     K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
Protein kinases [BR:ko01001]
 Serine/threonine protein kinases: Others
  PDHK family
   K12077  PDK1; pyruvate dehydrogenase kinase isoform 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
5163(PDK1)
PTR: 
459743(PDK1)
PPS: 
100968174(PDK1)
GGO: 
101150048(PDK1)
PON: 
100442853(PDK1)
MCC: 
697772(PDK1)
MMU: 
228026(Pdk1)
RNO: 
116551(Pdk1)
CFA: 
476828(PDK1)
AML: 
FCA: 
101092705(PDK1)
BTA: 
528655(PDK1)
SSC: 
100286871(PDK1)
ECB: 
100064091(PDK1)
MDO: 
100027741(PDK1)
SHR: 
100932777(PDK1)
OAA: 
100084173(PDK1)
GGA: 
425972(PDK1)
MGP: 
100551417
TGU: 
100218846(PDK1)
ACS: 
100555492(pdk1)
XLA: 
432080(pdk1) 494745
XTR: 
100497838
DRE: 
555840(pdk1)
TRU: 
101066998
OLA: 
101161766
TSP: 
Tsp_01211
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Balendran A, Casamayor A, Deak M, Paterson A, Gaffney P, Currie R, Downes CP, Alessi DR
  Title
PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.
  Journal
Curr Biol 9:393-404 (1999)
DBGET integrated database retrieval system