KEGG   ORTHOLOGY: K12170Help
Entry
K12170                      KO                                     

Name
RNF125
Definition
E3 ubiquitin-protein ligase RNF125 [EC:6.3.2.19]
Pathway
RIG-I-like receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04622 RIG-I-like receptor signaling pathway
    K12170  RNF125; E3 ubiquitin-protein ligase RNF125
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K12170  RNF125; E3 ubiquitin-protein ligase RNF125
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  single Ring-finger type E3
   Other single Ring-finger type E3
    K12170  RNF125; E3 ubiquitin-protein ligase RNF125
BRITE hierarchy
Genes
HSA: 
54941(RNF125)
PTR: 
743809(RNF125)
PPS: 
100973859(RNF125)
GGO: 
101130622(RNF125)
PON: 
100460705(RNF125)
MCC: 
706726(RNF125)
MCF: 
102122979(RNF125)
MMU: 
67664(Rnf125)
RNO: 
361296(Rnf125)
CGE: 
100775067(Rnf125)
HGL: 
101723725(Rnf125)
TUP: 
102503377(RNF125)
CFA: 
490498(RNF125)
AML: 
FCA: 
101086183(RNF125)
PTG: 
102948584(RNF125)
BTA: 
519541(RNF125)
BOM: 
102268900(RNF125)
PHD: 
102342530(RNF125)
CHX: 
102187179(RNF125)
SSC: 
100517591(RNF125)
CFR: 
102524108(RNF125)
BACU: 
102997822(RNF125)
LVE: 
103089350(RNF125)
ECB: 
100052335(RNF125)
MYB: 
102254436(RNF125)
MYD: 
102761039(RNF125)
PALE: 
102889932(RNF125)
MDO: 
100023988(RNF125)
SHR: 
100919305(RNF125)
APLA: 
101794545(RNF125)
CLV: 
102096131(RNF125)
ASN: 
102371695(RNF125)
AMJ: 
102574583(RNF125)
CMY: 
102938903(RNF125)
ACS: 
PBI: 
103060193(RNF125)
XTR: 
100493643(rnf125)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Giannini AL, Gao Y, Bijlmakers MJ
  Title
T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain.
  Journal
Biochem J 410:101-11 (2008)
Reference
  Authors
Zhao H, Li CC, Pardo J, Chu PC, Liao CX, Huang J, Dong JG, Zhou X, Huang Q, Huang B, Bennett MK, Molineaux SM, Lu H, Daniel-Issakani S, Payan DG, Masuda ES
  Title
A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation.
  Journal
J Immunol 174:5288-97 (2005)

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