KEGG ORTHOLOGY: K12298

ORTHOLOGY: K12298

Entry

K12298 KO

Name

CEL

Definition

bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13]

Pathway

ko00100	Steroid biosynthesis
ko00561	Glycerolipid metabolism
ko04972	Pancreatic secretion
ko04975	Fat digestion and absorption

Module

M00098

Acylglycerol degradation

Disease

H00410

Maturity onset diabetes of the young (MODY)

Brite

KEGG Orthology (KO) [BR:ko00001]
Metabolism
  Lipid metabolism
   00100 Steroid biosynthesis
    K12298  CEL; bile salt-stimulated lipase
   00561 Glycerolipid metabolism
    K12298  CEL; bile salt-stimulated lipase
Organismal Systems
  Digestive system
   04972 Pancreatic secretion
    K12298  CEL; bile salt-stimulated lipase
   04975 Fat digestion and absorption
    K12298  CEL; bile salt-stimulated lipase
KEGG pathway modules [BR:ko00002]
Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00098  Acylglycerol degradation
     K12298  CEL; bile salt-stimulated lipase
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.3  triacylglycerol lipase
     K12298  CEL; bile salt-stimulated lipase
    3.1.1.13  sterol esterase
     K12298  CEL; bile salt-stimulated lipase

Other DBs

RN:

R01462 R02250 R02687

GO:

0004806 0004771

Genes

HSA:	1056(CEL)
PTR:	473081(CEL)
PPS:	100969434(CEL)
GGO:	101144373
PON:	100451110
MCC:	722291(CEL)
MMU:	12613(Cel)
RNO:	24254(Cel)
CFA:	491280(CEL)
AML:	100472032(CEL)
FCA:	101080585(CEL)
BTA:	280748(CEL)
SSC:	100625953(CEL)
ECB:	100066592(CEL)
MDO:	100017734(CEL)
SHR:	100918682(CEL)
GGA:	417165(CEL)
MGP:	100539880
TGU:	100227302(CEL)
ACS:	100566622(cel)
XLA:	379474(cel) 380547(cel) 447025(cel) 495520
XTR:	100144991(cel) 100492444
DRE:	322481(cel.1) 573994(cell)
TRU:	101070169
OLA:	101172670 101172916

» show all

Reference

PMID:11514232

Authors

Lombardo D

Title

Bile salt-dependent lipase: its pathophysiological implications.

Journal

Biochim Biophys Acta 1533:1-28 (2001)

Reference

PMID:17205399

Authors

Whitcomb DC, Lowe ME

Title

Human pancreatic digestive enzymes.

Journal

Dig Dis Sci 52:1-17 (2007)

All links

Ontology (8)   
   KEGG BRITE (6)   
   GO (2)   
Pathway (57)   
   KEGG PATHWAY (10)   
   KEGG MODULE (47)   
Disease (1)   
   KEGG DISEASE (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (10)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
   KEGG RCLASS (5)   
Gene (69)   
   KEGG GENES (31)   
   KEGG DGENES (2)   
   KEGG EGENES (31)   
   KEGG MGENES (5)   
Protein sequence (16)   
   UniProt (16)   
Literature (2)   
   PubMed (2)   
All databases (164)   

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