| Entry |
|
| Name |
GLB1, ELNR1
|
| Definition |
|
| Pathway |
| Galactose metabolism | | Other glycan degradation | | Glycosaminoglycan degradation | | Sphingolipid metabolism | | Glycosphingolipid biosynthesis - ganglio series | | Lysosome |
|
| Module |
| Keratan sulfate degradation |
|
| Disease |
| Mucopolysaccharidosis type IV (MPS4) | | Galactosialidosis | | GM1 gangliosidosis |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
Metabolism
Carbohydrate metabolism
00052 Galactose metabolism
K12309 GLB1, ELNR1; beta-galactosidase
Lipid metabolism
00600 Sphingolipid metabolism
K12309 GLB1, ELNR1; beta-galactosidase
Glycan biosynthesis and metabolism
00531 Glycosaminoglycan degradation
K12309 GLB1, ELNR1; beta-galactosidase
00604 Glycosphingolipid biosynthesis - ganglio series
K12309 GLB1, ELNR1; beta-galactosidase
00511 Other glycan degradation
K12309 GLB1, ELNR1; beta-galactosidase
Cellular Processes
Transport and catabolism
04142 Lysosome
K12309 GLB1, ELNR1; beta-galactosidase
KEGG pathway modules [BR:ko00002]
Pathway module
Carbohydrate and lipid metabolism
Glycosaminoglycan metabolism
M00079 Keratan sulfate degradation
K12309 GLB1, ELNR1; beta-galactosidase
Enzymes [BR:ko01000]
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.23 beta-galactosidase
K12309 GLB1, ELNR1; beta-galactosidase
 |
| Other DBs |
|
| Genes |
HSA: | | PTR: | | PPS: | | GGO: | | PON: | | MCC: | | MMU: | | RNO: | | CFA: | | AML: | | FCA: | | BTA: | | ECB: | | MDO: | | SHR: | | OAA: | | GGA: | | MGP: | | TGU: | | ACS: | | XLA: | | XTR: | | DRE: | | TRU: | | OLA: | | BFO: | | SPU: | | DME: | | DPO: | | DAN: | | DER: | | DPE: | | DSE: | | DSI: | | DWI: | | DYA: | | DGR: | | DMO: | | DVI: | | AGA: | | AAG: | | CQU: | | AME: | | NVI: | | API: | | PHU: | | ISC: | | CEL: | | CBR: | | TSP: | | SMM: | | NVE: | | HMG: | | AQU: | | ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | ZMA: | | SMO: | | PPP: | | DDI: | | » show all
   |
| Reference |
|
| Authors |
Ohto U, Usui K, Ochi T, Yuki K, Satow Y, Shimizu T |
| Title |
Crystal structure of human beta-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases. |
| Journal |
J Biol Chem 287:1801-12 (2012) |