KEGG   ORTHOLOGY: K12309Help
Entry
K12309                      KO                                     

Name
GLB1, ELNR1
Definition
beta-galactosidase [EC:3.2.1.23]
Pathway
ko00052  Galactose metabolism
ko00511  Other glycan degradation
ko00531  Glycosaminoglycan degradation
ko00600  Sphingolipid metabolism
ko00604  Glycosphingolipid biosynthesis - ganglio series
ko01100  Metabolic pathways
ko04142  Lysosome
Module
M00079  Keratan sulfate degradation
Disease
H00123  Mucopolysaccharidosis type IV (MPS4)
H00276  Galactosialidosis
H00281  GM1 gangliosidosis
H00421  Mucopolysaccharidosis (MPS)
H00422  Glycoproteinoses
H00426  Defects in the degradation of ganglioside
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Carbohydrate metabolism
   00052 Galactose metabolism
    K12309  GLB1, ELNR1; beta-galactosidase
  Lipid metabolism
   00600 Sphingolipid metabolism
    K12309  GLB1, ELNR1; beta-galactosidase
  Glycan biosynthesis and metabolism
   00531 Glycosaminoglycan degradation
    K12309  GLB1, ELNR1; beta-galactosidase
   00604 Glycosphingolipid biosynthesis - ganglio series
    K12309  GLB1, ELNR1; beta-galactosidase
   00511 Other glycan degradation
    K12309  GLB1, ELNR1; beta-galactosidase
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    K12309  GLB1, ELNR1; beta-galactosidase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Glycosaminoglycan metabolism
    M00079  Keratan sulfate degradation
     K12309  GLB1, ELNR1; beta-galactosidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.23  beta-galactosidase
     K12309  GLB1, ELNR1; beta-galactosidase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12309  GLB1, ELNR1; beta-galactosidase
BRITE hierarchy
Other DBs
RN: R01678 R03355 R04633 R06010 R07807
GO: 0004565
Genes
HSA: 2720(GLB1)
PTR: 460254(GLB1)
PPS: 100978745(GLB1)
GGO: 101125280(GLB1)
PON: 100173272(GLB1)
NLE: 100586200(GLB1)
MCC: 709355(GLB1)
MCF: 102119163(GLB1) 102143665
CSAB: 103241840(GLB1)
RRO: 104669852(GLB1)
RBB: 108542762(GLB1)
SBQ: 101040891(GLB1)
MMU: 12091(Glb1)
RNO: 316033(Glb1)
CGE: 100767446(Glb1)
NGI: 103734471(Glb1)
HGL: 101712908(Glb1)
CCAN: 109693698(Glb1)
OCU: 100339251(GLB1)
TUP: 102468364(GLB1)
CFA: 403873(GLB1)
AML: 100474542(GLB1)
UMR: 103681027(GLB1)
ORO: 101367677(GLB1)
FCA: 493927(GLB1)
PTG: 102971976(GLB1)
AJU: 106988806(GLB1)
BTA: 507188(GLB1)
BOM: 102285166(GLB1)
BIU: 109576213(GLB1)
PHD: 102332524
CHX: 102178493(GLB1)
OAS: 101112930(GLB1)
SSC: 100624593(GLB1)
CFR: 102516561(GLB1)
CDK: 105090734(GLB1)
BACU: 103001448(GLB1)
OOR: 101271955(GLB1)
ECB: 100056330(GLB1)
EPZ: 103561107(GLB1)
EAI: 106838003(GLB1)
MYB: 102241480(GLB1)
MYD: 102756561(GLB1)
HAI: 109377940(GLB1)
RSS: 109445368(GLB1)
PALE: 102891983(GLB1)
LAV: 100664567(GLB1)
TMU: 101344867
MDO: 100028615(GLB1)
SHR: 100921364(GLB1)
OAA: 100084405(GLB1)
GGA: 420720(GLB1)
MGP: 100545525(GLB1)
CJO: 107309381(GLB1)
APLA: 101797465(GLB1) 101799366(GLB1L)
ACYG: 106041811(GLB1)
TGU: 100226450(GLB1)
GFR: 102036710(GLB1)
FAB: 101818101(GLB1)
PHI: 102104867(GLB1)
PMAJ: 107200231(GLB1)
CCW: 104688996(GLB1)
FPG: 101919160(GLB1)
FCH: 102049955(GLB1)
EGZ: 104132810(GLB1)
AAM: 106488991(GLB1) 106499145(GLB1L)
ASN: 102379496 102386509(GLB1)
AMJ: 102567630(GLB1)
PSS: 102445232(GLB1)
CMY: 102945910(GLB1)
CPIC: 101942048(GLB1L) 101948060(GLB1)
ACS: 100557584(glb1)
PVT: 110070703(GLB1) 110090768
PBI: 103055747(GLB1)
GJA: 107124019(GLB1)
XLA: 100158367(glb1l.L) 443705(glb1.L)
XTR: 496447(glb1) 548712(glb1l)
NPR: 108799646 108800723(GLB1)
DRE: 548343(glb1)
IPU: 108260601(glb1) 108266864
AMEX: 103023617(glb1) 111189184
TRU: 101061169 101062290(glb1)
LCO: 104919016 104926989(glb1)
MZE: 101477638(glb1) 101481174
OLA: 101167424(glb1) 101172034
PRET: 103461671 103466289(glb1)
NFU: 107375296(glb1) 107390105
CSEM: 103383516(glb1) 103392198
LCF: 108896517(glb1) 108901040
HCQ: 109511175(glb1) 109523341
BPEC: 110165251(glb1) 110166590
SASA: 106582563 106602547(glb1)
ELS: 105008340 105022847(glb1)
SFM: 108920707 108940743(glb1)
LCM: 102353144(GLB1L) 102357279(GLB1)
CMK: 103173635 103183377(glb1)
SPU: 587532
APLC: 110973405
SKO: 100373531
DME: Dmel_CG3132(Ect3) Dmel_CG9092(Gal)
DSI: Dsimw501_GD18795(Dsim_GD18795) Dsimw501_GD22613(Dsim_GD22613)
AME: 725756(GB17852)
BIM: 100742348
BTER: 100651050
SOC: 105199428
AEC: 105153952
ACEP: 105622732
PBAR: 105424837
CFO: 105258784
LHU: 105672808
PGC: 109851941
BMOR: 100302607(Gal)
ZNE: 110841440
FCD: 110859761
CEL: CELE_T19B10.3(bgal-1)
CBR: CBG23139
TSP: Tsp_04892
CRG: 105340763
OBI: 106870855
SHX: MS3_05332
AQU: 100634556
ATH: AT1G72990(BGAL17) AT3G52840(BGAL2)
THJ: 104812215
CIT: 102628668
TCC: 18596143
GRA: 105767722
GHI: 107906099
EGR: 104424130
GMX: 100783905
VRA: 106762651
VAR: 108334217
CCAJ: 109805759
CAM: 101511475
ADU: 107461437
AIP: 107612665
LJA: Lj3g3v0323160.1(Lj3g3v0323160.1) Lj3g3v0323160.2(Lj3g3v0323160.2)
LANG: 109351263
FVE: 101299375
PPER: 18784064
PMUM: 103327697
PAVI: 110759456
MDM: 103414756
PXB: 103933119
ZJU: 107425258
CSV: 101204972
CMO: 103502003
MCHA: 111016956
CMAX: 111467663
CMOS: 111449840
CPEP: 111801977
RCU: 8288580
JCU: 105631450
JRE: 108991647
VVI: 100251499
SLY: 101259643
SPEN: 107023295
SOT: 102586853
CANN: 107876085
NSY: 104237330
INI: 109187974
SIND: 105157758
OEU: 111367688
LSV: 111889048
DCR: 108223418
BVG: 104899813
SOE: 110785844
NNU: 104600699
OSA: 4339457
DOSA: Os05t0539400-01(Os05g0539400)
OBR: 102700340
BDI: 100828384
ATS: 109732741(LOC109732741)
SBI: 8068989
ZMA: 100502243
SITA: 101767820
PDA: 103721532
EGU: 105047685
MUS: 103984706
DCT: 110115366
AOF: 109820812
ATR: 18444788
APRO: F751_2864
DDI: DDB_G0290217(glb1)
DFA: DFA_01207(glb2)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Ohto U, Usui K, Ochi T, Yuki K, Satow Y, Shimizu T
  Title
Crystal structure of human beta-galactosidase: structural basis of Gm1 gangliosidosis and morquio B diseases.
  Journal
J Biol Chem 287:1801-12 (2012)
DOI:10.1074/jbc.M111.293795
  Sequence
[hsa:2720]
Reference
PMID:8922281
  Authors
Hinek A
  Title
Biological roles of the non-integrin elastin/laminin receptor.
  Journal
Biol Chem 377:471-80 (1996)
  Sequence
[hsa:2720]

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