KEGG   ORTHOLOGY: K12313Help
Entry
K12313                      KO                                     

Name
ACTA2
Definition
actin, aortic smooth muscle
Pathway
Vascular smooth muscle contraction
Apelin signaling pathway
Disease
H00801  
Familial thoracic aortic aneurysm and dissection (TAAD)
H01396  
Moyamoya Disease
H01630  
Patent ductus arteriosus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    K12313  ACTA2; actin, aortic smooth muscle
 Organismal Systems
  Circulatory system
   04270 Vascular smooth muscle contraction
    K12313  ACTA2; actin, aortic smooth muscle
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actins
    Actins
     K12313  ACTA2; actin, aortic smooth muscle
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K12313  ACTA2; actin, aortic smooth muscle
BRITE hierarchy
Genes
HSA: 
59(ACTA2)
PTR: 
466148(ACTA2)
PPS: 
100987623(ACTA2)
GGO: 
101151850(ACTA2)
PON: 
100173819(ACTA2)
NLE: 
100579983(ACTA2)
MCC: 
100427024(ACTA2)
MCF: 
102139312(ACTA2)
CSAB: 
103216222(ACTA2)
RRO: 
104675148(ACTA2)
CJC: 
100396597(ACTA2)
SBQ: 
101035102(ACTA2)
MMU: 
11475(Acta2)
RNO: 
81633(Acta2)
CGE: 
100758575(Acta2)
NGI: 
103738035(Acta2)
HGL: 
101718388(Acta2)
OCU: 
100009271(ACTA2)
TUP: 
102476173(ACTA2)
CFA: 
477587(ACTA2)
AML: 
100470496(ACTA2)
UMR: 
103661931(ACTA2)
FCA: 
101093547(ACTA2)
PTG: 
102950751(ACTA2)
AJU: 
106980969(ACTA2)
BTA: 
515610(ACTA2)
BOM: 
102274194(ACTA2)
PHD: 
102339866(ACTA2)
CHX: 
102191486(ACTA2)
OAS: 
101121051(ACTA2)
SSC: 
733615(ACTA2)
CFR: 
102516380(ACTA2)
BACU: 
103020047(ACTA2)
LVE: 
103076696(ACTA2)
ECB: 
100062175(ACTA2)
MYB: 
102259532(ACTA2)
MYD: 
102755942(ACTA2)
HAI: 
109377704(ACTA2)
PALE: 
102880134(ACTA2)
LAV: 
100658952(ACTA2)
MDO: 
100012397(ACTA2)
SHR: 
OAA: 
100074413(ACTA2)
GGA: 
423787(ACTA2)
MGP: 
100549984(ACTA2)
CJO: 
107315889(ACTA2)
APLA: 
101793497(ACTA2)
GFR: 
102033705(ACTA2)
FAB: 
101805665(ACTA2)
PHI: 
102102121(ACTA2)
CCW: 
104696526(ACTA2)
FPG: 
101915277(ACTA2)
FCH: 
102045674(ACTA2)
CLV: 
102084341(ACTA2)
AAM: 
106487836(ACTA2)
ASN: 
102372571(ACTA2)
AMJ: 
102577392(ACTA2)
PSS: 
102456465(ACTA2)
CMY: 
102939405(ACTA2)
CPIC: 
101937631(ACTA2)
ACS: 
100551887(acta2)
PBI: 
103064165(ACTA2)
GJA: 
107121656(ACTA2)
XLA: 
100653490 431847(acta2.L)
XTR: 
496696(acta2)
DRE: 
322509(acta2)
IPU: 
100304861(acta2)
TRU: 
TNG: 
LCO: 
104936549(acta2)
MZE: 
101471135(acta2)
OLA: 
XMA: 
SASA: 
LCM: 
BFO: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Munot P, Saunders DE, Milewicz DM, Regalado ES, Ostergaard JR, Braun KP, Kerr T, Lichtenbelt KD, Philip S, Rittey C, Jacques TS, Cox TC, Ganesan V
  Title
A novel distinctive cerebrovascular phenotype is associated with heterozygous Arg179 ACTA2 mutations.
  Journal
Brain 135:2506-14 (2012)
Reference
PMID:2701935
  Authors
Kamada S, Kakunaga T
  Title
The nucleotide sequence of a human smooth muscle alpha-actin (aortic type) cDNA.
  Journal
Nucleic Acids Res 17:1767 (1989)
  Sequence
[hsa:59]

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