KEGG   ORTHOLOGY: K12314Help
Entry
K12314                      KO                                     

Name
ACTC1
Definition
actin, alpha cardiac muscle
Pathway
ko04260  Cardiac muscle contraction
ko04261  Adrenergic signaling in cardiomyocytes
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00292  Hypertrophic cardiomyopathy (HCM)
H00294  Dilated cardiomyopathy (DCM)
H00546  Atrial septal defect
H01216  Left ventricular noncompaction (LVNC)
H01219  Restrictive cardiomyopathy (RCM)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Circulatory system
   04260 Cardiac muscle contraction
    K12314  ACTC1; actin, alpha cardiac muscle
   04261 Adrenergic signaling in cardiomyocytes
    K12314  ACTC1; actin, alpha cardiac muscle
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K12314  ACTC1; actin, alpha cardiac muscle
   05414 Dilated cardiomyopathy (DCM)
    K12314  ACTC1; actin, alpha cardiac muscle
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actins
    Actins
     K12314  ACTC1; actin, alpha cardiac muscle
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   K12314  ACTC1; actin, alpha cardiac muscle
  Exosomal proteins of bladder cancer cells
   K12314  ACTC1; actin, alpha cardiac muscle
BRITE hierarchy
Genes
HSA: 70(ACTC1)
PTR: 453307(ACTC1)
PPS: 100987752(ACTC1)
GGO: 101150071(ACTC1)
PON: 100442237
NLE: 100603570(ACTC1)
MCC: 697367(ACTC1)
MCF: 102135975(ACTC1)
CSAB: 103245896(ACTC1)
RRO: 104665644(ACTC1)
RBB: 108543689(ACTC1)
CJC: 100398865(ACTC1)
SBQ: 101037742(ACTC1)
MMU: 11464(Actc1)
RNO: 29275(Actc1)
CGE: 100766388(Actc1)
NGI: 103740516(Actc1)
HGL: 101723544(Actc1)
CCAN: 109677781(Actc1)
OCU: 100340339(ACTC1)
TUP: 102486241(ACTC1)
CFA: 478250(ACTC1)
AML: 100464234(ACTC1)
UMR: 103673559(ACTC1) 103679895
ORO: 101383699(ACTC1)
FCA: 101095586(ACTC1)
PTG: 102958158(ACTC1)
AJU: 106969798(ACTC1)
BTA: 533219(ACTC1)
BOM: 102266730(ACTC1)
BIU: 109564901(ACTC1)
PHD: 102322879(ACTC1)
CHX: 102170606(ACTC1)
OAS: 101111554(ACTC1)
SSC: 100152267(ACTC1)
CFR: 102524504(ACTC1)
CDK: 105089985(ACTC1)
BACU: 103001576(ACTC1)
LVE: 103074529(ACTC1)
OOR: 101287649(ACTC1)
ECB: 100057678(ACTC1)
EPZ: 103549173(ACTC1)
EAI: 106835151(ACTC1)
MYB: 102247353(ACTC1)
MYD: 102763375(ACTC1)
HAI: 109386250(ACTC1)
RSS: 109444276(ACTC1)
PALE: 102880535(ACTC1)
LAV: 100658146(ACTC1)
TMU: 101341415
MDO: 100026925(ACTC1)
SHR: 100918763
GGA: 423298(ACTC1)
MGP: 100303693(ACTC1)
CJO: 107314994(ACTC1)
APLA: 101792025(ACTC1)
ACYG: 106031717(ACTC1)
TGU: 100229664(ACTC1)
GFR: 102038037(ACTC1)
FAB: 101808145(ACTC1)
PHI: 102099989(ACTC1)
PMAJ: 107206305(ACTC1)
CCW: 104684380(ACTC1)
FPG: 101914921(ACTC1)
FCH: 102050360(ACTC1)
CLV: 102093431(ACTC1)
EGZ: 104126475(ACTC1)
AAM: 106482816(ACTC1)
ASN: 102373984(ACTC1)
AMJ: 106736711(ACTC1)
PSS: 102456632(ACTC1)
CMY: 102939680(ACTC1)
CPIC: 101944575(ACTC1)
ACS: 100560364(actc1) 100566451
PVT: 110076864(ACTC1) 110085534
XLA: 108699710 108716753 379752(actc1.L) 432314(acta1.L) 779129(act2)
XTR: 394673(act3) 394698(actc1) 394982(MGC75582) 448346(acta1)
DRE: 337770(si:ch73-187m15.4) 408256(actc1a) 570210(zgc:86709) 58114(actc1b)
PRET: 103457336 103458530 103458759(actc1) 103462807(acta1)
LCM: 102352337(ACTC1) 102364634
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Jiang HK, Qiu GR, Li-Ling J, Xin N, Sun KL
  Title
Reduced ACTC1 expression might play a role in the onset of congenital heart disease by inducing cardiomyocyte apoptosis.
  Journal
Circ J 74:2410-8 (2010)
DOI:10.1253/circj.CJ-10-0234
  Sequence
[hsa:70] [rno:29275]

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