KEGG   ORTHOLOGY: K12318Help
Entry
K12318                      KO                                     

Name
GUCY1A
Definition
guanylate cyclase soluble subunit alpha [EC:4.6.1.2]
Pathway
Purine metabolism
cGMP-PKG signaling pathway
Vascular smooth muscle contraction
Gap junction
Platelet activation
Circadian entrainment
Long-term depression
Oxytocin signaling pathway
Salivary secretion
Module
M00694  
cGMP signaling
Disease
H01396  
Moyamoya Disease
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00230 Purine metabolism
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
 Environmental Information Processing
  Signal transduction
   04022 cGMP - PKG signaling pathway
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
 Cellular Processes
  Cellular commiunity
   04540 Gap junction
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
 Organismal Systems
  Immune system
   04611 Platelet activation
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
  Endocrine system
   04921 Oxytocin signaling pathway
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
  Circulatory system
   04270 Vascular smooth muscle contraction
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
  Digestive system
   04970 Salivary secretion
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
  Nervous system
   04730 Long-term depression
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
  Environmental adaptation
   04713 Circadian entrainment
    K12318  GUCY1A; guanylate cyclase soluble subunit alpha
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00694  cGMP signaling
     K12318  GUCY1A; guanylate cyclase soluble subunit alpha
Enzymes [BR:ko01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.2  guanylate cyclase
     K12318  GUCY1A; guanylate cyclase soluble subunit alpha
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
2977(GUCY1A2) 2982(GUCY1A3)
PTR: 
100608597(GUCY1A3) 466769(GUCY1A2)
PPS: 
100985928(GUCY1A3) 100987635(GUCY1A2)
GGO: 
PON: 
100172608(GUCY1A3) 100445361(GUCY1A2)
NLE: 
100581660(GUCY1A3) 100592351(GUCY1A2)
MCC: 
699365(GUCY1A3) 706615(GUCY1A2)
MCF: 
CJC: 
100387768(GUCY1A2) 100396127(GUCY1A3)
MMU: 
234889(Gucy1a2) 60596(Gucy1a3)
RNO: 
497757(Gucy1a3) 66012(Gucy1a2)
CGE: 
100768699(Gucy1a3) 100769238(Gucy1a2)
NGI: 
103731324(Gucy1a2) 103751001(Gucy1a3)
HGL: 
101702803(Gucy1a2) 101712487(Gucy1a3)
OCU: 
100350099(GUCY1A3) 100357621(GUCY1A2)
TUP: 
102469297(GUCY1A2) 102483882(GUCY1A3)
CFA: 
479455(GUCY1A2) 482663(GUCY1A3)
AML: 
UMR: 
103658044(GUCY1A3) 103662433(GUCY1A2)
FCA: 
101098377(GUCY1A3) 101099494(GUCY1A2)
PTG: 
BTA: 
281216(GUCY1A3) 613600(GUCY1A2)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
100522091(GUCY1A2) 553100(GUCY1A3)
CFR: 
102508002(GUCY1A3) 102523651(GUCY1A2)
BACU: 
LVE: 
ECB: 
100069474(GUCY1A2) 100069573(GUCY1A3)
MYB: 
102250686(GUCY1A3) 102260196(GUCY1A2)
MYD: 
102764771(GUCY1A3) 102767033(GUCY1A2)
PALE: 
102889502(GUCY1A3) 102896673(GUCY1A2)
MDO: 
100017038(GUCY1A3) 100027037(GUCY1A2)
SHR: 
100928661(GUCY1A3) 100929308(GUCY1A2)
OAA: 
100075186(GUCY1A3) 100077965(GUCY1A2)
GGA: 
422407(GUCY1A3) 771678(GUCY1A2)
MGP: 
100542159(GUCY1A2) 100547213(GUCY1A3)
APLA: 
101790692(GUCY1A2) 101799600(GUCY1A3)
TGU: 
100217644(GUCY1A2) 100223563(GUCY1A3)
FAB: 
101812872(GUCY1A2) 101814320(GUCY1A3)
PHI: 
102106220(GUCY1A3) 102113474(GUCY1A2)
FPG: 
101914436(GUCY1A2) 101922339(GUCY1A3)
FCH: 
102046999(GUCY1A3) 102059430(GUCY1A2)
CLV: 
102090855(GUCY1A3) 102097143(GUCY1A2)
ASN: 
102383277(GUCY1A2) 102383335(GUCY1A3)
AMJ: 
102565323(GUCY1A3) 102569074(GUCY1A2)
PSS: 
102444454(GUCY1A2) 102446826(GUCY1A3)
CMY: 
102934622(GUCY1A2) 102938442(GUCY1A3)
ACS: 
100554615(gucy1a2) 100563220(gucy1a3)
PBI: 
103052921(GUCY1A2) 103063344(GUCY1A3)
XTR: 
100145454(gucy1a2) 100496677(gucy1a3)
DRE: 
550420(gucy1a3)
TRU: 
101068334 446059(frgcs-alpha1)
MZE: 
OLA: 
100049177(gucy1a3) 100049248(olgcs-alpha2) 101172871
XMA: 
LCM: 
CMK: 
103185780(gucy1a2) 103187183(gucy1a3)
CIN: 
SPU: 
DME: 
Dmel_CG1912(Gycalpha99B)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
AAG: 
CQU: 
AME: 
408879(sGC-alpha1)
NVI: 
TCA: 
BMOR: 
100642185(GC-a1)
API: 
PHU: 
ISC: 
LGI: 
HMG: 
TAD: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Fitzpatrick DA, O'Halloran DM, Burnell AM
  Title
Multiple lineage specific expansions within the guanylyl cyclase gene family.
  Journal
BMC Evol Biol 6:26 (2006)

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