KEGG   ORTHOLOGY: K12330Help
Entry
K12330                      KO                                     
Name
ARHGEF1
Definition
Rho guanine nucleotide exchange factor 1
Pathway
Vascular smooth muscle contraction
Regulation of actin cytoskeleton
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
 Organismal Systems
  Circulatory system
   04270 Vascular smooth muscle contraction
    K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    K12330  ARHGEF1; Rho guanine nucleotide exchange factor 1
BRITE hierarchy
Other DBs
GO: 
Genes
HSA: 
9138(ARHGEF1)
PTR: 
456067(ARHGEF1)
PPS: 
100972918(ARHGEF1)
GGO: 
101131951(ARHGEF1)
PON: 
100438951(ARHGEF1)
MCC: 
722198(ARHGEF1)
MMU: 
16801(Arhgef1)
RNO: 
60323(Arhgef1)
CFA: 
AML: 
100477081(ARHGEF1)
FCA: 
101083892(ARHGEF1)
BTA: 
513377(ARHGEF1)
SSC: 
100518073(ARHGEF1)
XTR: 
100037905(arhgef1)
TRU: 
101072427
OLA: 
101157484
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Guilluy C, Bregeon J, Toumaniantz G, Rolli-Derkinderen M, Retailleau K, Loufrani L, Henrion D, Scalbert E, Bril A, Torres RM, Offermanns S, Pacaud P, Loirand G
  Title
The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure.
  Journal
Nat Med 16:183-90 (2010)
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