KEGG   ORTHOLOGY: K12344Help
Entry
K12344                      KO                                     

Name
SRD5A2
Definition
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Pathway
Steroid hormone biosynthesis
Prostate cancer
Disease
H00608  
46,XY disorders of sex development (Disorders in androgen synthesis or action)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00140 Steroid hormone biosynthesis
    K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
 Human Diseases
  Cancers
   05215 Prostate cancer
    K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     K12344  SRD5A2; 3-oxo-5-alpha-steroid 4-dehydrogenase 2
BRITE hierarchy
Other DBs
Genes
HSA: 
6716(SRD5A2)
PTR: 
100614992(SRD5A2)
PPS: 
100986960(SRD5A2)
GGO: 
101138758(SRD5A2)
PON: 
100454013(SRD5A2)
MCC: 
705676(SRD5A2)
MCF: 
102115639(SRD5A2)
MMU: 
94224(Srd5a2)
RNO: 
64677(Srd5a2)
CGE: 
HGL: 
101708836(Srd5a2)
TUP: 
102478179(SRD5A2)
CFA: 
403715(SRD5A2)
AML: 
FCA: 
101086898(SRD5A2)
PTG: 
102953790(SRD5A2)
BTA: 
527024(SRD5A2)
BOM: 
102271230(SRD5A2)
PHD: 
102326516(SRD5A2)
CHX: 
102187232(SRD5A2)
OAS: 
100820756(SRD5A2)
SSC: 
397048(ST5AR2)
CFR: 
102523831(SRD5A2)
BACU: 
LVE: 
103084942(SRD5A2)
ECB: 
100070655(SRD5A2)
MYB: 
102242056(SRD5A2)
MYD: 
102773080(SRD5A2)
PALE: 
102884992(SRD5A2)
MDO: 
100031489(SRD5A2)
SHR: 
OAA: 
100078235(SRD5A2)
GGA: 
772291(SRD5A2)
MGP: 
TGU: 
100225484(SRD5A2)
FAB: 
101808258(SRD5A2)
PHI: 
102108406(SRD5A2)
APLA: 
101799397(SRD5A2)
FPG: 
101919492(SRD5A2)
FCH: 
102046391(SRD5A2)
CLV: 
102085278(SRD5A2)
ASN: 
102380562(SRD5A2)
AMJ: 
102573116(SRD5A2)
PSS: 
102451701(SRD5A2)
CMY: 
102936118(SRD5A2)
ACS: 
PBI: 
XTR: 
549867(srd5a2)
DRE: 
550388(srd5a2b) 550398(srd5a2a)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103181748(srd5a2)
HMG: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Caglayan AO, Dundar M, Tanriverdi F, Baysal NA, Unluhizarci K, Ozkul Y, Borlu M, Batukan C, Kelestimur F
  Title
Idiopathic hirsutism: local and peripheral expression of aromatase (CYP19A) and 5alpha-reductase genes (SRD5A1 and SRD5A2).
  Journal
Fertil Steril 96:479-82 (2011)

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