KEGG   ORTHOLOGY: K12348Help
Entry
K12348                      KO                                     

Name
ASAH1
Definition
acid ceramidase [EC:3.5.1.23]
Pathway
Sphingolipid metabolism
Sphingolipid signaling pathway
Lysosome
Module
M00099  
Sphingosine biosynthesis
Disease
H00138  
Farber lipogranulomatosis
H00424  
Defects in the degradation of sphingomyelin
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    K12348  ASAH1; acid ceramidase
 Environmental Information Processing
  Signal transduction
   04071 Sphingolipid signaling pathway
    K12348  ASAH1; acid ceramidase
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    K12348  ASAH1; acid ceramidase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00099  Sphingosine biosynthesis
     K12348  ASAH1; acid ceramidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23  ceramidase
     K12348  ASAH1; acid ceramidase
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C89
   K12348  ASAH1; acid ceramidase
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12348  ASAH1; acid ceramidase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
427(ASAH1)
PTR: 
464022(ASAH1)
PPS: 
100991999(ASAH1)
GGO: 
101149522(ASAH1)
PON: 
100171626(ASAH1)
NLE: 
100579536(ASAH1)
MCC: 
703699(ASAH1)
MCF: 
102118393(ASAH1)
CSAB: 
103215400(ASAH1)
RRO: 
104655223(ASAH1)
RBB: 
108526474(ASAH1)
CJC: 
100409902(ASAH1)
SBQ: 
101044863(ASAH1)
MMU: 
11886(Asah1)
RNO: 
84431(Asah1)
CGE: 
100771068(Asah1)
NGI: 
103748255(Asah1)
HGL: 
101724913(Asah1)
CCAN: 
109692105(Asah1)
OCU: 
100338209(ASAH1)
TUP: 
102490603(ASAH1)
CFA: 
482897(ASAH1)
AML: 
100471625(ASAH1)
UMR: 
103681376(ASAH1)
FCA: 
101082231(ASAH1)
PTG: 
102969154(ASAH1)
AJU: 
106988336(ASAH1)
BTA: 
510620(ASAH1)
BOM: 
102285015(ASAH1)
BIU: 
109553501(ASAH1)
PHD: 
102326915(ASAH1)
CHX: 
102169733(ASAH1)
OAS: 
101117904(ASAH1)
SSC: 
100512932(ASAH1)
CFR: 
102503963(ASAH1)
CDK: 
105102375(ASAH1)
BACU: 
103004383(ASAH1)
LVE: 
103084758(ASAH1)
ECB: 
100054433(ASAH1)
EPZ: 
103556309(ASAH1)
EAI: 
106828200(ASAH1)
MYB: 
102261355(ASAH1)
MYD: 
102772524(ASAH1)
HAI: 
109394586(ASAH1)
RSS: 
109450556(ASAH1)
PALE: 
102884758(ASAH1)
LAV: 
100658494(ASAH1)
MDO: 
100021204(ASAH1)
SHR: 
100927628(ASAH1)
OAA: 
100093499(ASAH1)
GGA: 
422727(ASAH1)
MGP: 
100550236(ASAH1)
CJO: 
107313735(ASAH1)
APLA: 
101801719(ASAH1)
ACYG: 
106035211(ASAH1)
TGU: 
100223185(ASAH1)
GFR: 
102045042(ASAH1)
FAB: 
101806040(ASAH1)
PHI: 
102108790(ASAH1)
PMAJ: 
107203488(ASAH1)
CCW: 
104690859(ASAH1)
FPG: 
101917300(ASAH1)
FCH: 
102045851(ASAH1)
CLV: 
102098583(ASAH1)
AAM: 
106490075(ASAH1)
ASN: 
102383990(ASAH1)
AMJ: 
102566045(ASAH1)
PSS: 
102444687(ASAH1)
CMY: 
102930137(ASAH1)
CPIC: 
101944232(ASAH1)
ACS: 
100565312(asah1)
PVT: 
110077885(ASAH1)
PBI: 
103052913(ASAH1)
GJA: 
107108734(ASAH1)
XLA: 
447327(asah1.L)
XTR: 
100485700(asah1)
NPR: 
108785692(ASAH1)
DRE: 
393549(asah1b) 450068(asah1a)
SRX: 
SANH: 
SGH: 
IPU: 
108260777(asah1) 108269357(ASAH1)
TRU: 
101065149(asah1)
TNG: 
LCO: 
104936951(asah1)
NCC: 
104967119(asah1)
MZE: 
101476420(asah1)
OLA: 
101161703(asah1)
XMA: 
102231620(asah1)
CSEM: 
103384334(asah1)
LCF: 
HCQ: 
109511169(asah1)
BPEC: 
110167588(asah1)
SASA: 
ELS: 
105022854(asah1)
SFM: 
108924408(asah1)
LCM: 
102355600(ASAH1)
CMK: 
103178195(asah1)
BFO: 
CIN: 
SPU: 
SKO: 
DPX: 
ISC: 
CEL: 
CELE_F27E5.1(asah-2) CELE_K11D2.2(asah-1)
CBR: 
CBG00863 CBG15381(Cbr-asah-1)
NAI: 
TSP: 
HRO: 
LGI: 
CRG: 
OBI: 
LAK: 
NVE: 
ADF: 
HMG: 
TAD: 
MIS: 
MBR: 
SRE: 
DFA: 
TET: 
SMIN: 
v1.2.005120.t1(symbB.v1.2.005120.t1) v1.2.007250.t1(symbB.v1.2.007250.t1) v1.2.025307.t1(symbB.v1.2.025307.t1) v1.2.029508.t1(symbB.v1.2.029508.t1)
NGR: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8955159
  Authors
Koch J, Gartner S, Li CM, Quintern LE, Bernardo K, Levran O, Schnabel D, Desnick RJ, Schuchman EH, Sandhoff K
  Title
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease.
  Journal
J Biol Chem 271:33110-5 (1996)
DOI:10.1074/jbc.271.51.33110
  Sequence
[hsa:427]

DBGET integrated database retrieval system