KEGG   ORTHOLOGY: K12348Help
Entry
K12348                      KO                                     

Name
ASAH1
Definition
acid ceramidase [EC:3.5.1.23]
Pathway
Sphingolipid metabolism
Lysosome
Module
M00099  
Sphingosine biosynthesis
Disease
H00138  
Farber lipogranulomatosis
H00424  
Defects in the degradation of sphingomyelin
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00600 Sphingolipid metabolism
    K12348  ASAH1; acid ceramidase
 Cellular Processes
  Transport and catabolism
   04142 Lysosome
    K12348  ASAH1; acid ceramidase
KEGG pathway modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00099  Sphingosine biosynthesis
     K12348  ASAH1; acid ceramidase
Enzymes [BR:ko01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.1  In linear amides
    3.5.1.23  ceramidase
     K12348  ASAH1; acid ceramidase
Peptidases [BR:ko01002]
 Cysteine Peptidases
  Family C89
   K12348  ASAH1; acid ceramidase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
HSA: 
427(ASAH1)
PTR: 
464022(ASAH1)
PPS: 
100991999(ASAH1)
GGO: 
101149522(ASAH1)
PON: 
100171626(ASAH1)
MCC: 
703699(ASAH1)
MCF: 
102118393(ASAH1)
MMU: 
11886(Asah1)
RNO: 
84431(Asah1)
CGE: 
HGL: 
101724913(Asah1)
TUP: 
102490603(ASAH1)
CFA: 
482897(ASAH1)
AML: 
FCA: 
101082231(ASAH1)
BTA: 
510620(ASAH1)
BOM: 
102285015(ASAH1)
PHD: 
102326915(ASAH1)
CHX: 
102169733(ASAH1)
SSC: 
CFR: 
102503963(ASAH1)
ECB: 
100054433(ASAH1)
MYB: 
102261355(ASAH1)
MDO: 
SHR: 
100927628(ASAH1)
OAA: 
GGA: 
422727(ASAH1)
MGP: 
TGU: 
100223185(ASAH1)
FAB: 
101806040(ASAH1)
PHI: 
102108790(ASAH1)
APLA: 
101801719(ASAH1)
FPG: 
101917300(ASAH1)
FCH: 
102045851(ASAH1)
CLV: 
102098583(ASAH1)
ASN: 
102383990(ASAH1)
PSS: 
ACS: 
XLA: 
447327(asah1)
XTR: 
100485700(asah1)
DRE: 
393549(asah1b) 450068(asah1a)
TRU: 
101065149(ASAH)
MZE: 
OLA: 
XMA: 
LCM: 
102355600(ASAH1)
BFO: 
CIN: 
SPU: 
ISC: 
CEL: 
CELE_K11D2.2(asah-1)
CBR: 
CBG00863 CBG15381(Cbr-asah-1)
TSP: 
NVE: 
HMG: 
TAD: 
MIS: 
MBR: 
DFA: 
 » show all
TaxonomyKoalaUniProt
Reference
PMID:8955159
  Authors
Koch J, Gartner S, Li CM, Quintern LE, Bernardo K, Levran O, Schnabel D, Desnick RJ, Schuchman EH, Sandhoff K
  Title
Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification Of the first molecular lesion causing Farber disease.
  Journal
J Biol Chem 271:33110-5 (1996)

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