KEGG ORTHOLOGY: K12362

ORTHOLOGY: K12362

Entry

K12362                      KO

Symbol

RASGRP3

Name

RAS guanyl-releasing protein 3

Pathway

map04010

MAPK signaling pathway

map04014

Ras signaling pathway

map04015

Rap1 signaling pathway

map04662

B cell receptor signaling pathway

map05200

Pathways in cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K12362  RASGRP3; RAS guanyl-releasing protein 3
   04014 Ras signaling pathway
    K12362  RASGRP3; RAS guanyl-releasing protein 3
   04015 Rap1 signaling pathway
    K12362  RASGRP3; RAS guanyl-releasing protein 3
09150 Organismal Systems
  09151 Immune system
   04662 B cell receptor signaling pathway
    K12362  RASGRP3; RAS guanyl-releasing protein 3
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K12362  RASGRP3; RAS guanyl-releasing protein 3
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K12362  RASGRP3; RAS guanyl-releasing protein 3
Domain-containing proteins not elsewhere classified [BR:ko04990]
EF-hand domain-containing proteins
  Other EF-hand domain-containing proteins
   K12362  RASGRP3; RAS guanyl-releasing protein 3

Other DBs

GO:

0005088

Genes

HSA:	25780(RASGRP3)

PTR:	470348(RASGRP3)

PPS:	100973444(RASGRP3)

GGO:	101147649(RASGRP3)

PON:	100171706(RASGRP3)

NLE:	100603635(RASGRP3)

HMH:	116480555(RASGRP3)

MCC:	707225(RASGRP3)

MCF:	102136095(RASGRP3)

MTHB:

126934266

MNI:	105464819(RASGRP3)

CSAB:

103220524(RASGRP3)

CATY:

105578391(RASGRP3)

PANU:

101001477(RASGRP3)

TGE:	112604574(RASGRP3)

MLEU:

105542614(RASGRP3)

RRO:	104669440(RASGRP3)

RBB:	108528680(RASGRP3)

TFN:	117062489(RASGRP3)

PTEH:

111545404(RASGRP3)

CANG:

105507492(RASGRP3)

CJC:	100404102(RASGRP3)

SBQ:	101043633(RASGRP3)

CIMI:

108308850(RASGRP3)

CSYR:

103272652

MMUR:

105884482(RASGRP3)

LCAT:

123636786(RASGRP3)

PCOQ:

105816884(RASGRP3)

OGA:	100955151(RASGRP3)

MMU:	240168(Rasgrp3)

MCAL:

110312642(Rasgrp3)

MPAH:

110335530(Rasgrp3)

RNO:	313874(Rasgrp3)

MCOC:

116079748(Rasgrp3)

ANU:	117717216(Rasgrp3)

MUN:	110562664(Rasgrp3)

CGE:	100764463(Rasgrp3)

MAUA:

101834186(Rasgrp3)

PROB:

127220138(Rasgrp3)

PLEU:

114695916(Rasgrp3)

MORG:

121433070(Rasgrp3)

MFOT:

126514223

AAMP:

119806793(Rasgrp3)

NGI:	103746759(Rasgrp3)

HGL:	101717811(Rasgrp3)

CPOC:

100712845(Rasgrp3)

CCAN:

109694257(Rasgrp3)

DORD:

105983753(Rasgrp3)

DSP:	122102090(Rasgrp3)

PLOP:

125356569(Rasgrp3)

NCAR:

124963581

MMMA:

107137363(Rasgrp3)

OCU:

100342183

OPI:	101528696(RASGRP3)

TUP:	102498774(RASGRP3)

GVR:	103586838 103597236

CFA:	611329(RASGRP3)

CLUD:

112664548(RASGRP3)

VVP:	112933007(RASGRP3)

VLG:	121491177(RASGRP3)

NPO:	129511099(RASGRP3)

AML:	100484622(RASGRP3)

UMR:	103671590(RASGRP3)

UAH:	113241175(RASGRP3)

UAR:	123799845(RASGRP3)

ELK:

111158513

LLV:

125108393

MPUF:

101690986(RASGRP3)

MNP:	132021284(RASGRP3)

MLK:	131840530(RASGRP3)

NVS:	122915157(RASGRP3)

ORO:	101371588(RASGRP3)

EJU:	114219657(RASGRP3)

ZCA:	113937489(RASGRP3)

MLX:	118007758(RASGRP3)

NSU:	110587286(RASGRP3)

LWW:	102727777(RASGRP3)

FCA:	101085456(RASGRP3)

PYU:	121044329(RASGRP3)

PCOO:

112864119(RASGRP3)

PBG:	122466911(RASGRP3)

PVIV:

125162196(RASGRP3)

LRUF:

124503577

PTG:	102954264(RASGRP3)

PPAD:

109266029(RASGRP3)

PUC:

125937543

AJU:

106967894

HHV:	120244026(RASGRP3)

BTA:	523745(RASGRP3)

BOM:	102267127(RASGRP3)

BIU:	109565967(RASGRP3)

BBUB:

102410345(RASGRP3)

BBIS:

104980950(RASGRP3)

CHX:	102190608(RASGRP3)

OAS:	101101969(RASGRP3)

BTAX:

128055903(RASGRP3)

ODA:	120851660(RASGRP3)

CCAD:

122441553(RASGRP3)

MBEZ:

129539227(RASGRP3)

SSC:	100511446(RASGRP3)

CFR:	102506193(RASGRP3)

CBAI:

105078955(RASGRP3)

CDK:	105095517(RASGRP3)

VPC:	102539130(RASGRP3)

BACU:

103011501(RASGRP3)

BMUS:

118906428(RASGRP3)

LVE:	103070705(RASGRP3)

OOR:	101289392(RASGRP3)

DLE:	111174894(RASGRP3)

PCAD:

102983100(RASGRP3)

PSIU:

116764722(RASGRP3)

NASI:

112391116(RASGRP3)

ECB:	100070505(RASGRP3)

EPZ:	103558532(RASGRP3)

EAI:	106839887(RASGRP3)

MYB:	102254297(RASGRP3)

MYD:	102754347(RASGRP3)

MMYO:

118669112(RASGRP3)

MLF:	102420246(RASGRP3)

PKL:	118717122(RASGRP3)

EFUS:

103283126(RASGRP3)

MNA:	107541820(RASGRP3)

DRO:	112297824(RASGRP3)

SHON:

119001280(RASGRP3)

AJM:	119050336(RASGRP3)

PDIC:

114500279(RASGRP3)

PHAS:

123811574(RASGRP3)

MMF:	118630520(RASGRP3)

PPAM:

129066346(RASGRP3)

HAI:	109388799(RASGRP3)

RFQ:	117033403(RASGRP3)

PALE:

102888491(RASGRP3)

PGIG:

120621790(RASGRP3)

PVP:	105300076(RASGRP3)

RAY:	107505744(RASGRP3)

MJV:	108387321(RASGRP3)

TOD:	119259413(RASGRP3)

SARA:

101544723(RASGRP3)

SETR:

126023857(RASGRP3)

LAV:	100664201(RASGRP3)

TMU:

101360110

ETF:	101664472(RASGRP3)

DNM:	101430010(RASGRP3)

MDO:	100031591(RASGRP3)

GAS:	123237050(RASGRP3)

SHR:	100913998(RASGRP3)

AFZ:

127548645

PCW:	110198182(RASGRP3)

OAA:	100080124(RASGRP3)

GGA:	421460(RASGRP3)

PCOC:

116229146(RASGRP3)

MGP:	100539029(RASGRP3)

CJO:	107311289(RASGRP3)

TPAI:

128081129(RASGRP3)

LMUT:

125689864(RASGRP3)

NMEL:

110395671(RASGRP3)

APLA:

101790483(RASGRP3)

ACYG:

106029670(RASGRP3)

CATA:

118254707(RASGRP3)

AFUL:

116488345(RASGRP3)

TGU:	100229237(RASGRP3)

LSR:	110477906(RASGRP3)

SCAN:

103817484(RASGRP3)

PMOA:

120506902(RASGRP3)

OTC:	121335821(RASGRP3)

PRUF:

121358810(RASGRP3)

GFR:	102041260(RASGRP3)

FAB:	101810860(RASGRP3)

OMA:	130251073(RASGRP3)

PHI:	102113324(RASGRP3)

PMAJ:

107201851(RASGRP3)

CCAE:

111926964(RASGRP3)

CCW:	104684363(RASGRP3)

CBRC:

103624133(RASGRP3)

ETL:	114065392(RASGRP3)

ZAB:	102063415(RASGRP3)

ACHL:

103808255(RASGRP3)

SVG:	106853221(RASGRP3)

MMEA:

130575840(RASGRP3)

HRT:	120750743(RASGRP3)

FPG:	101911870(RASGRP3)

FCH:	102049292(RASGRP3)

CLV:	102091020(RASGRP3)

EGZ:	104124127(RASGRP3)

NNI:	104018674(RASGRP3)

PCRI:

104033207(RASGRP3)

PLET:

104627901(RASGRP3)

EHS:	104504507(RASGRP3)

ACUN:

113478681(RASGRP3)

TALA:

104360033(RASGRP3)

PADL:

103922848(RASGRP3)

AFOR:

103902687(RASGRP3)

ACHC:

115350352(RASGRP3)

HALD:

104320661(RASGRP3)

HLE:	104840334(RASGRP3)

AGEN:

126051509

GCL:

127014499

CCRI:

104164080(RASGRP3)

CSTI:

104558909(RASGRP3)

CMAC:

104473755

MUI:	104548321(RASGRP3)

BREG:

104636973(RASGRP3)

FGA:	104073683(RASGRP3)

GSTE:

104263899(RASGRP3)

LDI:	104348160(RASGRP3)

MNB:	103780984(RASGRP3)

OHA:	104329276(RASGRP3)

NNT:	104407224(RASGRP3)

SHAB:

115613685(RASGRP3)

DPUB:

104299959(RASGRP3)

PGUU:

104461654(RASGRP3)

ACAR:

104527903(RASGRP3)

CPEA:

104397297(RASGRP3)

AVIT:

104268376

CVF:	104282315(RASGRP3)

RTD:	128907629(RASGRP3)

CUCA:

104058191(RASGRP3)

TEO:	104374168(RASGRP3)

BRHI:

104487972(RASGRP3)

AAM:	106485481(RASGRP3)

AROW:

112973411(RASGRP3)

NPD:	112957536(RASGRP3)

TGT:	104576866(RASGRP3)

DNE:	112997157(RASGRP3)

SCAM:

104151681(RASGRP3)

ASN:	102382991(RASGRP3)

AMJ:	102577025(RASGRP3)

CPOO:

109319877(RASGRP3)

GGN:	109304607(RASGRP3)

PSS:	102453442(RASGRP3)

CMY:	102940270(RASGRP3)

CCAY:

125633800(RASGRP3)

DCC:	119853954(RASGRP3)

CPIC:

101944566(RASGRP3)

TST:	117874607(RASGRP3)

CABI:

116819069(RASGRP3)

MRV:	120402105(RASGRP3)

ACS:	100560305(rasgrp3)

ASAO:

132761275(RASGRP3)

PVT:	110089042(RASGRP3)

SUND:

121919115(RASGRP3)

PBI:	103056770(RASGRP3)

PMUR:

107289694(RASGRP3)

CTIG:

120307730(RASGRP3)

TSR:	106543020(RASGRP3)

PGUT:

117671874(RASGRP3)

APRI:

131188633(RASGRP3)

PTEX:

113433142(RASGRP3)

NSS:	113420749(RASGRP3)

VKO:	123033808(RASGRP3)

PMUA:

114594505(RASGRP3)

PRAF:

128410951(RASGRP3)

ZVI:	118081795(RASGRP3)

HCG:	128348190(RASGRP3)

GJA:	107113460(RASGRP3)

STOW:

125426028(RASGRP3)

EMC:	129343032(RASGRP3)

XLA:	108716683(rasgrp3.L) 108717828(rasgrp3.S)

XTR:	100487452(rasgrp3)

NPR:	108784170(RASGRP3)

RTEM:

120937522(RASGRP3)

BBUF:

120998745(RASGRP3)

BGAR:

122935658(RASGRP3)

MUO:	115465780(RASGRP3)

GSH:	117357677(RASGRP3)

DRE:	563441(rasgrp3)

SRX:	107744459 107755973

SANH:

107670874 107689794

SGH:	107553408(rasgrp3) 107583647

CCAR:

109070463 109072003 109077378

CAUA:

113113693 113117133

CGIB:

127976175 128031741

PTET:

122361807(rasgrp3)

LROH:

127179330(rasgrp3)

OMC:	131522954(rasgrp3)

PPRM:

120477711(rasgrp3)

RKG:	130097429(rasgrp3)

MAMB:

125268731(rasgrp3)

CIDE:

127498373

MASI:

127411156 127455550

TROS:

130560593(rasgrp3)

TDW:	130436652(rasgrp3)

MANU:

129417504(rasgrp3)

IPU:

108269749

IFU:	128612675(rasgrp3)

PHYP:

113547730(rasgrp3)

SMEO:

124390165(rasgrp3)

TFD:	113662041(rasgrp3)

TVC:	132852002(rasgrp3)

AMEX:

103040612(rasgrp3)

CMAO:

118823184(rasgrp3)

EEE:	113591719(rasgrp3)

CHAR:

105911596(rasgrp3)

LCO:	104936034(rasgrp3)

TBEN:

117475884 117476075(rasgrp3)

CGOB:

115020482(rasgrp3)

PGEO:

117459822(rasgrp3)

GACU:

117550667(rasgrp3)

EMAC:

134858894(rasgrp3)

ELY:	117248788(rasgrp3)

EFO:	125903962(rasgrp3)

PLEP:

121954834(rasgrp3)

SLUC:

116064554(rasgrp3)

ECRA:

117960582(rasgrp3)

ESP:	116705728(rasgrp3)

PFLV:

114572113(rasgrp3)

GAT:	120820445(rasgrp3)

PPUG:

119214286(rasgrp3)

AFB:	129092292(rasgrp3)

CLUM:

117743982(rasgrp3)

PSWI:

130207012(rasgrp3)

MSAM:

119917380(rasgrp3)

SCHU:

122884779(rasgrp3)

CUD:	121511060(rasgrp3)

MZE:	101478031(rasgrp3)

ONL:	109194145(rasgrp3)

OAU:	116333746(rasgrp3)

OLA:	101172059 105353619(rasgrp3)

OML:

112140997

CSAI:

133463662(rasgrp3)

XMA:	102217565(rasgrp3)

XCO:	114138554(rasgrp3)

XHE:	116712874(rasgrp3)

PRET:

103476548(rasgrp3)

PFOR:

103153120(rasgrp3)

PLAI:

106964690(rasgrp3)

PMEI:

106903385(rasgrp3)

GAF:	122842590(rasgrp3)

PPRL:

129356737 129360148

CVG:	107092582(rasgrp3)

CTUL:

119771882(rasgrp3)

GMU:	124859535(rasgrp3)

NFU:	107373003 107374414

KMR:	108242469(rasgrp3)

ALIM:

106513388(rasgrp3)

AOCE:

111586516(rasgrp3)

MCEP:

125019224(rasgrp3)

CSEM:

103387702(rasgrp3)

POV:	109629944(rasgrp3)

SSEN:

122782229(rasgrp3)

HHIP:

117775293(rasgrp3)

HSP:	118118849(rasgrp3)

SMAU:

118283501(rasgrp3)

LCF:

108895765

SDU:	111236432(rasgrp3)

SLAL:

111647051(rasgrp3)

XGL:	120796640(rasgrp3)

HCQ:	109523135(rasgrp3)

SSCV:

125978488

SBIA:

133509394(rasgrp3)

PEE:	133409782(rasgrp3)

PTAO:

133485385(rasgrp3)

BPEC:

110158152(rasgrp3)

MALB:

109960048(rasgrp3)

SJO:	128372869(rasgrp3)

SASA:

106576952 106606711

STRU:

115153175 115193819

OTW:	112252969(rasgrp3) 112254212

OMY:	110502432 110528321(rasgrp3)

OGO:	124038232 124041289(rasgrp3)

ONE:	115113248 115135152

OKI:	109889905 109899698

OKE:	118369668(rasgrp3) 118400476

SALP:

111952076 111977356

SNH:	120017621 120045625

CCLU:

121553501(rasgrp3) 121570227

ELS:	105023235(rasgrp3)

SFM:	108918082(rasgrp3)

PKI:	111849035(rasgrp3)

AANG:

118218213(rasgrp3)

LOC:	102698976(rasgrp3)

PSPA:

121315677 121316755

ARUT:

117403108 117411472

PSEX:

120516567(rasgrp3)

LCM:	102353784(RASGRP3)

CMK:	103181767(rasgrp3)

CPLA:

122552667(rasgrp3)

HOC:	132819678(rasgrp3)

LERI:

129699489(rasgrp3)

PMRN:

116943359 116947706

LRJ:	133341462 133342233

BFO:

BBEL:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

FOC:

TPAL:

ZNE:

CSEC:

BROR:

FCD:

DPX:	DAPPUDRAFT_30396

DMK:

DSV:

RSAN:

RMP:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LOA:	LOAG_03412

LGI:	LOTGIDRAFT_132094

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

LAK:

NVE:

EPA:

AMIL:

PDAM:

SPIS:

DGT:

AQU:	100635858 100637689

» show all

Reference

PMID:10934204

Authors

Rebhun JF, Castro AF, Quilliam LA

Title

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.

Journal

J Biol Chem 275:34901-8 (2000)
DOI:10.1074/jbc.M005327200

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (10)   
   KEGG PATHWAY (10)   
Gene (1125)   
   KEGG GENES (462)   
   KEGG MGENES (263)   
   RefGene (395)   
   OC (5)   
Literature (1)   
   PubMed (1)   
All databases (1139)   

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