KEGG   ORTHOLOGY: K12473Help
Entry
K12473                      KO                                     

Name
LDLR
Definition
low-density lipoprotein receptor
Pathway
Endocytosis
Ovarian steroidogenesis
Bile secretion
Toxoplasmosis
Hepatitis C
Disease
H00155  
Hypercholesterolemia
H01383  
LDL Receptor Disorder
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K12473  LDLR; low-density lipoprotein receptor
 Organismal Systems
  Endocrine system
   04913 Ovarian Steroidogenesis
    K12473  LDLR; low-density lipoprotein receptor
  Digestive system
   04976 Bile secretion
    K12473  LDLR; low-density lipoprotein receptor
 Human Diseases
  Infectious diseases
   05160 Hepatitis C
    K12473  LDLR; low-density lipoprotein receptor
   05145 Toxoplasmosis
    K12473  LDLR; low-density lipoprotein receptor
BRITE hierarchy
Genes
HSA: 
3949(LDLR)
PTR: 
455722(LDLR)
PPS: 
100974202(LDLR)
GGO: 
101124590(LDLR)
PON: 
100447659(LDLR)
MCC: 
574283(LDLR)
MCF: 
102127361(LDLR)
MMU: 
16835(Ldlr)
RNO: 
300438(Ldlr)
CGE: 
100689399(Ldlr)
HGL: 
101703463(Ldlr)
TUP: 
102484417(LDLR)
CFA: 
100683160(LDLR)
AML: 
FCA: 
101080362(LDLR)
PTG: 
102949981(LDLR)
BTA: 
281276(LDLR)
BOM: 
102268224(LDLR)
PHD: 
102334400(LDLR)
CHX: 
102186579(LDLR)
SSC: 
396801(LDLR)
CFR: 
102506814(LDLR)
BACU: 
103002602(LDLR)
LVE: 
103088391(LDLR)
ECB: 
100057389(LDLR)
MYB: 
102246709(LDLR)
MYD: 
102771350(LDLR)
PALE: 
102888790(LDLR)
MDO: 
654363(LDLR)
SHR: 
100923750(LDLR)
OAA: 
100079454(LDLR)
ASN: 
102370878(LDLR)
AMJ: 
102574674(LDLR)
CMY: 
102937401(LDLR)
ACS: 
PBI: 
XLA: 
373644(ldlr-b) 397757(ldlr-a)
XTR: 
DRE: 
387529(ldlra)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103187554(ldlr)
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Martinez-Olivan J, Arias-Moreno X, Velazquez-Campoy A, Millet O, Sancho J
  Title
LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat.
  Journal
FEBS J 281:1534-46 (2014)
Reference
  Authors
Goldstein JL, Brown MS
  Title
The LDL receptor.
  Journal
Arterioscler Thromb Vasc Biol 29:431-8 (2009)

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