KEGG   ORTHOLOGY: K12567Help
Entry
K12567                      KO                                     

Name
TTN
Definition
titin [EC:2.7.11.1]
Pathway
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00292  Hypertrophic cardiomyopathy (HCM)
H00294  Dilated cardiomyopathy (DCM)
H00593  Limb-girdle muscular dystrophy (LGMD)
H00594  Distal myopathy
H01976  Tibial muscular dystrophy
Brite
KEGG Orthology (KO) [BR:ko00001]
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K12567  TTN; titin
   05414 Dilated cardiomyopathy (DCM)
    K12567  TTN; titin
Enzymes [BR:ko01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     K12567  TTN; titin
Protein kinases [BR:ko01001]
 Serine/threonine kinases: CAMK group
  MLCK family
   K12567  TTN; titin
Membrane trafficking [BR:ko04131]
 Others
  Actin-binding proteins
   Others
    K12567  TTN; titin
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Others
     K12567  TTN; titin
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K12567  TTN; titin
BRITE hierarchy
Genes
HSA: 7273(TTN)
PTR: 459784(TTN)
PPS: 100994495(TTN)
GGO: 101126591(TTN)
PON: 100435464(TTN)
NLE: 100602111(TTN)
MCC: 703527(TTN)
MCF: 102118847(TTN)
CSAB: 103217425(TTN)
RRO: 104677536(TTN)
RBB: 108527098(TTN)
CJC: 100396664(TTN)
SBQ: 101030681
MMU: 22138(Ttn)
RNO: 84015(Ttn)
CGE: 100767264(Ttn)
NGI: 103751793(Ttn)
HGL: 101717863(Ttn)
CCAN: 109695426(Ttn)
OCU: 100008570(TTN)
TUP: 102500174(TTN)
AML: 100476638(TTN)
UMR: 103659915(TTN)
ORO: 101365205(TTN)
FCA: 101080315(TTN)
PTG: 102958083(TTN)
AJU: 106988330(TTN)
BOM: 102270908(TTN)
BIU: 109566003(TTN)
PHD: 102318859(TTN)
CHX: 102173234(TTN)
OAS: 101122837(TTN)
SSC: 100519519(TTN)
CFR: 102520668(TTN)
CDK: 105098680(TTN)
BACU: 103014327
LVE: 103074022
OOR: 101287117(TTN)
ECB: 100053844(TTN)
EPZ: 103547978
EAI: 106826586(TTN)
MYB: 102252525(TTN)
MYD: 102766243(TTN)
HAI: 109388924(TTN)
RSS: 109451227(TTN)
PALE: 102893689(TTN)
LAV: 104845494
TMU: 101353907
SHR: 100923152(TTN)
OAA: 103171044(TTN)
MGP: 100546807(TTN)
CJO: 107316616
APLA: 101789520(TTN)
ACYG: 106029845(TTN)
TGU: 100230340(TTN)
GFR: 102045044(TTN)
FAB: 101819370(TTN)
PHI: 102110498(TTN) 106628041
PMAJ: 107207342(TTN)
CCW: 104694159(TTN) 109145671
FPG: 101921795(TTN)
FCH: 102055507(TTN)
CLV: 102097216
EGZ: 104132701(TTN)
AAM: 106499120(TTN)
ASN: 102384137(TTN)
AMJ: 102568392(TTN)
PSS: 102451731 102452728(TTN)
CPIC: 101932983 101933242(TTN)
ACS: 100560476(ttn) 103280171
PVT: 110084610(TTN)
PBI: 103063864(TTN)
GJA: 107112583(TTN)
XTR: 105948415
NPR: 108791207(TTN)
DRE: 100001684(ttn.1) 317731(ttn.2)
IPU: 108266288(ttn) 108266290
LCM: 102365068(TTN)
CIN: 100178935(con)
DME: Dmel_CG14964(CG14964) Dmel_CG1915(sls)
DSI: Dsimw501_GD13415(Dsim_GD13415) Dsimw501_GD17604(Dsim_GD17604)
AME: 551259(zormin)
BMOR: 100141452(Titin1) 100141454(Projectin) 692378(Kettin)
PXY: 105384109
TUT: 107361033
CEL: CELE_F54E2.3(ketn-1)
CBR: CBG06318(Cbr-ketn-1)
BMY: Bm1_54260
TSP: Tsp_05689
MYI: 110458512
EPA: 110232235
ADF: 107339449
HMG: 100212532
SPAR: SPRG_19863
AFS: AFR_22960
SACI: Sinac_4765
NMR: Nmar_1073
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9804419
  Authors
Mayans O, van der Ven PF, Wilm M, Mues A, Young P, Furst DO, Wilmanns M, Gautel M
  Title
Structural basis for activation of the titin kinase domain during myofibrillogenesis.
  Journal
Nature 395:863-9 (1998)
DOI:10.1038/27603
  Sequence
[hsa:7273]

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