KEGG   ORTHOLOGY: K12641Help
Entry
K12641                      KO                                     

Name
LMNA
Definition
lamin A/C
Pathway
ko04210  Apoptosis
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05412  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
ko05414  Dilated cardiomyopathy (DCM)
Disease
H00264  Charcot-Marie-Tooth disease (CMT)
H00294  Dilated cardiomyopathy (DCM)
H00420  Familial partial lipodystrophy (FPL)
H00563  Emery-Dreifuss muscular dystrophy
H00590  Congenital muscular dystrophies (CMD/MDC)
H00593  Limb-girdle muscular dystrophy (LGMD)
H00601  Hutchinson-Gilford progeria syndrome
H00663  Restrictive dermopathy
H00665  Mandibuloacral dysplasia
H01216  Left ventricular noncompaction (LVNC)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    K12641  LMNA; lamin A/C
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K12641  LMNA; lamin A/C
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    K12641  LMNA; lamin A/C
   05414 Dilated cardiomyopathy (DCM)
    K12641  LMNA; lamin A/C
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type V: Nuclear lamins
     K12641  LMNA; lamin A/C
BRITE hierarchy
Other DBs
GO: 0005638
Genes
HSA: 4000(LMNA)
PTR: 457385(LMNA)
PPS: 100982001(LMNA)
GGO: 101139250(LMNA)
PON: 100432939(LMNA)
NLE: 100603145(LMNA)
MCC: 719414(LMNA)
MCF: 102125659(LMNA)
CSAB: 103223838(LMNA)
RRO: 104664914(LMNA)
RBB: 108515510(LMNA)
CJC: 100401580(LMNA)
SBQ: 101052183(LMNA)
MMU: 16905(Lmna)
RNO: 60374(Lmna)
CGE: 100757316(Lmna)
NGI: 103750617(Lmna)
HGL: 101704567(Lmna)
CCAN: 109690469(Lmna)
OCU: 100343574(LMNA)
TUP: 102492596(LMNA)
CFA: 480124(LMNA)
AML: 100469629(LMNA)
UMR: 103668357(LMNA)
ORO: 101383303(LMNA)
FCA: 101086199(LMNA)
PTG: 102967799(LMNA)
BTA: 404144(LMNA)
BOM: 102280217(LMNA)
BIU: 109553357(LMNA)
PHD: 102334072(LMNA)
CHX: 102175347(LMNA)
OAS: 101107924(LMNA)
SSC: 100126859(LMNA)
CFR: 102520067(LMNA)
CDK: 105105658(LMNA)
BACU: 103007926(LMNA) 103008965
LVE: 103081139(LMNA)
OOR: 101283048(LMNA)
ECB: 100057663(LMNA)
EPZ: 103548822(LMNA)
EAI: 106828474(LMNA)
MYB: 102262486(LMNA)
MYD: 102769953(LMNA)
HAI: 109393421(LMNA)
RSS: 109434321(LMNA)
PALE: 102884955(LMNA)
LAV: 100662965(LMNA)
TMU: 101345325
MDO: 100017764(LMNA)
SHR: 100923083(LMNA)
OAA: 100086283(LMNA)
GGA: 396224(LMNA)
CJO: 107324328(LMNA)
APLA: 101797969(LMNA)
ACYG: 106048973(LMNA)
TGU: 100218522(LMNA)
GFR: 102031639(LMNA)
FAB: 101813508(LMNA)
PHI: 102101987(LMNA)
PMAJ: 107214592(LMNA)
CCW: 104683093(LMNA)
FPG: 101917405(LMNA)
FCH: 102055756(LMNA)
CLV: 102091664
EGZ: 104124057(LMNA)
AAM: 106492305(LMNA)
PSS: 102443460(LMNA) 102459838
CMY: 102948145(LMNA)
ACS: 100553155(lmna)
PVT: 110091219(LMNA)
PBI: 103057051(LMNA)
GJA: 107111455 107118044(LMNA)
XLA: 108700440 108700617 373673(lmna.L)
XTR: 733973(lmna)
NPR: 108799663(LMNA)
DRE: 195815(lmna)
IPU: 108267994(lmna)
AMEX: 103035739
TRU: 101072260 101077373(lmna)
LCO: 104928071 104932162(lmna)
MZE: 101466330(lmna) 101476203
PRET: 103473032 103477552(lmna)
NFU: 107379121(lmna) 107394894
LCF: 108899256 108899430(lmna)
HCQ: 109513571 109521011(lmna)
ELS: 105007923 105031464(lmna)
SFM: 108926783(lmna) 108930411
LCM: 102359604(LMNA)
CMK: 103187531
SKO: 100303476(if-1)
SPAR: SPRG_14046
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
De Vos WH, Houben F, Hoebe RA, Hennekam R, van Engelen B, Manders EM, Ramaekers FC, Broers JL, Van Oostveldt P
  Title
Increased plasticity of the nuclear envelope and hypermobility of telomeres due to the loss of A-type lamins.
  Journal
Biochim Biophys Acta 1800:448-58 (2010)
DOI:10.1016/j.bbagen.2010.01.002
  Sequence
[hsa:4000]

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