KEGG   ORTHOLOGY: K12646Help
Entry
K12646                      KO                                     

Name
DDX58, RIG-I
Definition
ATP-dependent RNA helicase DDX58 [EC:3.6.3.14]
Pathway
NF-kappa B signaling pathway
RIG-I-like receptor signaling pathway
Cytosolic DNA-sensing pathway
Hepatitis C
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Epstein-Barr virus infection
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
 Organismal Systems
  Immune system
   04622 RIG-I-like receptor signaling pathway
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   04623 Cytosolic DNA-sensing pathway
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
 Human Diseases
  Infectious diseases
   05162 Measles
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   05164 Influenza A
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   05161 Hepatitis B
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   05160 Hepatitis C
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   05168 Herpes simplex infection
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
   05169 Epstein-Barr virus infection
    K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.3  Acting on acid anhydrides to catalyse transmembrane movement of substances
    3.6.3.14  H+-transporting two-sector ATPase
     K12646  DDX58, RIG-I; ATP-dependent RNA helicase DDX58
BRITE hierarchy
Genes
HSA: 
23586(DDX58)
PTR: 
465035(DDX58)
PPS: 
100967985(DDX58)
GGO: 
101135326(DDX58)
PON: 
100443290(DDX58)
NLE: 
100606548(DDX58)
MCC: 
704638(DDX58)
MCF: 
102141351(DDX58)
CJC: 
100408692(DDX58)
MMU: 
230073(Ddx58)
RNO: 
297989(Ddx58)
CGE: 
100766319(Ddx58)
NGI: 
103748447(Ddx58)
HGL: 
101717131(Ddx58)
OCU: 
100347707(DDX58)
CFA: 
100855560(DDX58)
AML: 
UMR: 
103667020(DDX58)
FCA: 
101095926(DDX58)
PTG: 
102953066(DDX58)
BTA: 
504760(DDX58)
BOM: 
102280551(DDX58)
PHD: 
102335349(DDX58)
CHX: 
102183788(DDX58)
OAS: 
101107257(DDX58)
SSC: 
396723(DDX58)
CFR: 
102524392(DDX58)
BACU: 
103020032(DDX58)
LVE: 
103089123(DDX58)
ECB: 
100067920(DDX58)
MYB: 
MYD: 
102751776(DDX58)
PALE: 
102881037(DDX58)
OAA: 
100078060(DDX58)
APLA: 
101789567(DDX58)
TGU: 
100222705(DDX58)
FAB: 
101809434(DDX58)
PHI: 
102107316(DDX58)
FPG: 
101917977(DDX58)
FCH: 
102047325(DDX58)
CLV: 
102098789(DDX58)
ASN: 
102388849(DDX58)
AMJ: 
102565282(DDX58)
PSS: 
102452744(DDX58)
CMY: 
102936061(DDX58)
ACS: 
PBI: 
103062221(DDX58)
XTR: 
100495207(ddx58)
LCM: 
102361129(DDX58)
CMK: 
103187211(ddx58)
BFO: 
CIN: 
SPU: 
CEL: 
CBR: 
CBG08270(Cbr-drh-3)
BMY: 
LOA: 
HRO: 
LGI: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yoneyama M, Kikuchi M, Natsukawa T, Shinobu N, Imaizumi T, Miyagishi M, Taira K, Akira S, Fujita T
  Title
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses.
  Journal
Nat Immunol 5:730-7 (2004)

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