KEGG   ORTHOLOGY: K12647Help
Entry
K12647                      KO                                     

Name
IFIH1, MDA5
Definition
interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13]
Pathway
RIG-I-like receptor signaling pathway
Hepatitis B
Measles
Influenza A
Herpes simplex infection
Disease
H00408  
Type I diabetes mellitus
Brite
KEGG Orthology (KO) [BR:ko00001]
 Organismal Systems
  Immune system
   04622 RIG-I-like receptor signaling pathway
    K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
 Human Diseases
  Infectious diseases
   05162 Measles
    K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
   05164 Influenza A
    K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
   05161 Hepatitis B
    K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
   05168 Herpes simplex infection
    K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.13  RNA helicase
     K12647  IFIH1, MDA5; interferon-induced helicase C domain-containing protein 1
BRITE hierarchy
Genes
HSA: 
64135(IFIH1)
PTR: 
459692(IFIH1)
PPS: 
100981559(IFIH1)
GGO: 
101142588(IFIH1)
PON: 
100438807(IFIH1)
MCC: 
702024(IFIH1)
MCF: 
102135560(IFIH1)
MMU: 
71586(Ifih1)
RNO: 
499801(Ifih1)
CGE: 
100767593(Ifih1)
HGL: 
101721395(Ifih1)
TUP: 
102476561(IFIH1)
CFA: 
488371(IFIH1)
AML: 
100467176(IFIH1)
FCA: 
101099233(IFIH1)
PTG: 
102970672(IFIH1)
BTA: 
535490(IFIH1)
BOM: 
102266380(IFIH1)
PHD: 
102330121(IFIH1)
CHX: 
102183188(IFIH1)
OAS: 
101106234(IFIH1)
SSC: 
100101927(IFIH1)
CFR: 
102520863(IFIH1)
BACU: 
103014106(IFIH1)
LVE: 
103086848(IFIH1)
ECB: 
100061257(IFIH1)
MYB: 
102241185(IFIH1)
MYD: 
102760067(IFIH1)
PALE: 
102888688(IFIH1)
MDO: 
100022390(IFIH1)
SHR: 
100915060(IFIH1)
OAA: 
100082294(IFIH1)
GGA: 
424185(IFIH1)
MGP: 
100545639(IFIH1)
APLA: 
101800076(IFIH1)
TGU: 
100222644(IFIH1) 100225529(IFIH1)
FAB: 
101809185(IFIH1)
PHI: 
102107885(IFIH1)
FPG: 
101916011(IFIH1)
FCH: 
102051096(IFIH1)
CLV: 
102091175(IFIH1)
ASN: 
102384738(IFIH1)
AMJ: 
102560357(IFIH1)
PSS: 
102443714(IFIH1)
CMY: 
102943181(IFIH1)
ACS: 
100553529(ifih1)
PBI: 
103050994(IFIH1)
XTR: 
100488298(ifih1)
DRE: 
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102365428(IFIH1)
CMK: 
103176369(ifih1)
BFO: 
SPU: 
NVE: 
AQU: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Kang DC, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, Fisher PB
  Title
mda-5: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties.
  Journal
Proc Natl Acad Sci U S A 99:637-42 (2002)

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