KEGG   ORTHOLOGY: K12743Help
Entry
K12743                      KO                                     

Name
PCBAB
Definition
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase [EC:6.3.2.26]
Pathway
Penicillin and cephalosporin biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Biosynthesis of other secondary metabolites
   00311 Penicillin and cephalosporin biosynthesis
    K12743  PCBAB; N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.26  N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
     K12743  PCBAB; N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Nonribosomal peptide synthetase (NRPS)
  Linear NRPS
   K12743  PCBAB; N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase
BRITE hierarchy
Other DBs
RN: 
GO: 
Genes
ANI: 
AOR: 
AOR_1_920074(AO090038000543)
AFV: 
ABE: 
TVE: 
SCT: 
SCAT_5684(pcbAB)
SCY: 
TaxonomyKoalaUniProt
Reference
PMID:2061333
  Authors
MacCabe AP, van Liempt H, Palissa H, Unkles SE, Riach MB, Pfeifer E, von Dohren H, Kinghorn JR
  Title
Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Aspergillus nidulans. Molecular characterization of the acvA gene encoding the first enzyme of the penicillin biosynthetic pathway.
  Journal
J Biol Chem 266:12646-54 (1991)

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