KEGG   ORTHOLOGY: K12757Help
Entry
K12757                      KO                                     

Name
MYL12
Definition
myosin regulatory light chain 12
Pathway
Focal adhesion
Tight junction
Platelet activation
Leukocyte transendothelial migration
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:ko00001]
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    K12757  MYL12; myosin regulatory light chain 12
  Cellular commiunity
   04510 Focal adhesion
    K12757  MYL12; myosin regulatory light chain 12
   04530 Tight junction
    K12757  MYL12; myosin regulatory light chain 12
 Organismal Systems
  Immune system
   04611 Platelet activation
    K12757  MYL12; myosin regulatory light chain 12
   04670 Leukocyte transendothelial migration
    K12757  MYL12; myosin regulatory light chain 12
Cytoskeleton proteins [BR:ko04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Myosins
     K12757  MYL12; myosin regulatory light chain 12
Exosome [BR:ko04147]
 Exosomal proteins
  Exosomal proteins of bladder cancer cells
   K12757  MYL12; myosin regulatory light chain 12
BRITE hierarchy
Genes
HSA: 
103910(MYL12B) 10627(MYL12A)
PTR: 
455313(MYL12B) 455314(MYL12A)
PPS: 
100977626 100977910(MYL12B) 100978696(MYL12A)
GGO: 
PON: 
100172271(MYL12A) 100450310(MYL12B)
NLE: 
100585479(MYL12B) 100586474(MYL12A) 100600508
MCC: 
694957(MYL12B) 695077(MYL12A)
MCF: 
CJC: 
MMU: 
67268(Myl12a) 67938(Myl12b)
RNO: 
501203(Myl12a) 50685(Myl12b)
CGE: 
HGL: 
TUP: 
CFA: 
480193(MYL12B) 607207(MYL12A)
AML: 
UMR: 
FCA: 
PTG: 
BTA: 
100336093 531505(MYL12A) 614055(MYL12B)
BOM: 
PHD: 
CHX: 
OAS: 
SSC: 
414399(MRLC2) 733637
CFR: 
BACU: 
LVE: 
ECB: 
MYB: 
MYD: 
PALE: 
MDO: 
SHR: 
OAA: 
GGA: 
396284(MYL12A) 770011
MGP: 
APLA: 
TGU: 
FAB: 
PHI: 
FPG: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
380472(myl12b)
XTR: 
448060(myl12b)
DRE: 
337084(myl12.2)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsim_GD16204(Dsim_sqh)
DWI: 
DYA: 
Dyak_GE16476(Dyak_sqh)
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
AME: 
550973(GB17693) 552638(GB18838)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG01858(Cbr-mlc-2.2) CBG01859(Cbr-mlc-1) CBG09860(Cbr-mlc-4)
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
NVE: 
HMG: 
TAD: 
AQU: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
DSQ: 
SHS: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT67432(AGABI1DRAFT_67432)
ABV: 
AGABI2DRAFT196727(AGABI2DRAFT_196727)
CPUT: 
SLA: 
PFP: 
PGR: 
MLR: 
EIN: 
EHE: 
NCE: 
MBR: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Park I, Han C, Jin S, Lee B, Choi H, Kwon JT, Kim D, Kim J, Lifirsu E, Park WJ, Park ZY, Kim do H, Cho C
  Title
Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.
  Journal
Biochem J 434:171-80 (2011)
  Sequence
[mmu:67268 67938]
Reference
  Authors
Suizu F, Ueda K, Iwasaki T, Murata-Hori M, Hosoya H
  Title
Activation of actin-activated MgATPase activity of myosin II by phosphorylation with MAPK-activated protein kinase-1b (RSK-2).
  Journal
J Biochem 128:435-40 (2000)
  Sequence
[hsa:103910]

DBGET integrated database retrieval system