KEGG   ORTHOLOGY: K13240Help
Entry
K13240                      KO                                     

Name
NOS1
Definition
nitric-oxide synthase, brain [EC:1.14.13.39]
Pathway
ko00220  Arginine biosynthesis
ko00330  Arginine and proline metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04020  Calcium signaling pathway
ko04145  Phagosome
ko04371  Apelin signaling pathway
ko04713  Circadian entrainment
ko04730  Long-term depression
ko04926  Relaxin signaling pathway
ko04970  Salivary secretion
ko05010  Alzheimer's disease
ko05014  Amyotrophic lateral sclerosis (ALS)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Amino acid metabolism
   00220 Arginine biosynthesis
    K13240  NOS1; nitric-oxide synthase, brain
   00330 Arginine and proline metabolism
    K13240  NOS1; nitric-oxide synthase, brain
 Environmental Information Processing
  Signal transduction
   04371 Apelin signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
   04020 Calcium signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
 Cellular Processes
  Transport and catabolism
   04145 Phagosome
    K13240  NOS1; nitric-oxide synthase, brain
 Organismal Systems
  Endocrine system
   04926 Relaxin signaling pathway
    K13240  NOS1; nitric-oxide synthase, brain
  Digestive system
   04970 Salivary secretion
    K13240  NOS1; nitric-oxide synthase, brain
  Nervous system
   04730 Long-term depression
    K13240  NOS1; nitric-oxide synthase, brain
  Environmental adaptation
   04713 Circadian entrainment
    K13240  NOS1; nitric-oxide synthase, brain
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    K13240  NOS1; nitric-oxide synthase, brain
   05014 Amyotrophic lateral sclerosis (ALS)
    K13240  NOS1; nitric-oxide synthase, brain
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     K13240  NOS1; nitric-oxide synthase, brain
BRITE hierarchy
Other DBs
RN: R00111 R00557 R00558
GO: 0004517
Genes
HSA: 4842(NOS1)
PTR: 467139(NOS1)
PPS: 100996089(NOS1)
GGO: 101147071(NOS1)
PON: 100433069(NOS1)
NLE: 100597250(NOS1)
MCC: 693781(NOS1)
MCF: 102123521(NOS1)
RRO: 104675533(NOS1)
RBB: 108539288(NOS1)
CJC: 100895717(NOS1)
SBQ: 101034544(NOS1)
MMU: 18125(Nos1)
RNO: 24598(Nos1)
CGE: 100758127(Nos1)
NGI: 103745523(Nos1)
HGL: 101711993(Nos1)
CCAN: 109686387(Nos1)
OCU: 100009243(NOS1)
TUP: 102480558(NOS1)
CFA: 477498(NOS1)
AML: 100468087(NOS1)
UMR: 103661304(NOS1)
ORO: 101375441(NOS1)
FCA: 101100342(NOS1)
PTG: 102962715(NOS1)
AJU: 106971710(NOS1)
BTA: 536132(NOS1)
BOM: 102280537(NOS1)
BIU: 109571319(NOS1)
PHD: 102317388(NOS1)
CHX: 102185490(NOS1)
OAS: 443533(NOS1)
SSC: 100520934(NOS1)
CFR: 102508946(NOS1)
CDK: 105104911(NOS1) 105106782
BACU: 103008209(NOS1)
LVE: 103090138(NOS1)
OOR: 101273057(NOS1)
ECB: 100051079(NOS1)
EPZ: 103547950(NOS1)
EAI: 106839766(NOS1)
MYB: 102260489(NOS1)
MYD: 102763635(NOS1)
HAI: 109382238(NOS1)
RSS: 109459480(NOS1)
PALE: 102884569(NOS1)
LAV: 100673992(NOS1)
TMU: 101342004
MDO: 100013712(NOS1)
SHR: 100921140(NOS1)
OAA: 100079842(NOS1)
GGA: 427721(NOS1)
MGP: 100538441(NOS1)
CJO: 107321466(NOS1)
APLA: 101798766(NOS1)
ACYG: 106045554(NOS1)
TGU: 100231414(NOS1)
GFR: 102042821(NOS1)
FAB: 101820761(NOS1)
PHI: 102106809(NOS1)
PMAJ: 107211573(NOS1)
CCW: 104695038(NOS1)
FPG: 101916747(NOS1)
FCH: 102047821(NOS1)
CLV: 102093432(NOS1)
EGZ: 104129871(NOS1)
AAM: 106493898(NOS1)
ASN: 102380334(NOS1)
AMJ: 102561243(NOS1)
PSS: 102444149(NOS1)
CMY: 102941829(NOS1)
CPIC: 101937660(NOS1)
ACS: 100562233(nos1)
PVT: 110070797 110090104(NOS1)
PBI: 103052972(NOS1)
GJA: 107112296(NOS1)
XLA: 108707179(nos1.S) 373705(nos1.L)
XTR: 100497595(nos1)
NPR: 108785232(NOS1)
DRE: 60658(nos1)
SRX: 107726721 107755829(nos1)
SGH: 107599142(nos1) 107599638
IPU: 108255344(nos1)
AMEX: 103046065(nos1)
TRU: 101066909(nos1)
LCO: 104923687(nos1)
NCC: 104967506(nos1)
MZE: 101485683(nos1)
OLA: 100049502(nos1)
XMA: 102233853(nos1)
PRET: 103469871(nos1)
NFU: 107386248(nos1)
CSEM: 103396877 103397851(nos1)
LCF: 108903114(nos1)
HCQ: 109525272(nos1)
BPEC: 110155016(nos1)
ELS: 105031277(nos1)
SFM: 108927312(nos1)
LCM: 102348281(NOS1)
CMK: 103184386(nos1)
CIN: 100183039
DME: Dmel_CG6713(Nos)
DSI: Dsimw501_GD22223(Dsim_GD22223)
AAG: 5572370
AME: 503861(NOS)
BIM: 100749227
BTER: 100650517
SOC: 105200228
AEC: 105149468
PBAR: 105432905
HST: 105183230
CFO: 105250272
LHU: 105675559
PGC: 109856190
NVI: 100313941(Nos)
TCA: 655549
DPA: 109546644
NVL: 108558954
BMOR: 100144542(NOS2) 692510(NOS1)
API: 100160390
DNX: 107172687
ZNE: 110828058
FCD: 110850636
TUT: 107370056
CRG: 105322950
MYI: 110460719
OBI: 106875654
LAK: 106169208
HMG: 101240122
 » show all
TaxonomyKoalaUniProt
Reference
PMID:7528745
  Authors
Hall AV, Antoniou H, Wang Y, Cheung AH, Arbus AM, Olson SL, Lu WC, Kau CL, Marsden PA
  Title
Structural organization of the human neuronal nitric oxide synthase gene (NOS1).
  Journal
J Biol Chem 269:33082-90 (1994)
  Sequence
[hsa:4842]

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