KEGG   ORTHOLOGY: K13305Help
Entry
K13305                      KO                                     

Name
NEDD4L
Definition
E3 ubiquitin-protein ligase NEDD4-like [EC:6.3.2.19]
Pathway
Ubiquitin mediated proteolysis
Endocytosis
Aldosterone-regulated sodium reabsorption
Brite
KEGG Orthology (KO) [BR:ko00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like
 Organismal Systems
  Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like
Enzymes [BR:ko01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.19  ubiquitin---protein ligase
     K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like
Ubiquitin system [BR:ko04121]
 Ubiquitin ligases (E3)
  HECT type E3
   K13305  NEDD4L; E3 ubiquitin-protein ligase NEDD4-like
BRITE hierarchy
Genes
HSA: 
23327(NEDD4L)
PTR: 
455443(NEDD4L)
PPS: 
100974611(NEDD4L)
GGO: 
101145073(NEDD4L)
PON: 
100172429(NEDD4L)
MCC: 
700282(NEDD4L)
MCF: 
MMU: 
83814(Nedd4l)
RNO: 
291553(Nedd4l)
HGL: 
101715398(Nedd4l)
TUP: 
102485790(NEDD4L)
CFA: 
476189(NEDD4L)
AML: 
100477591(NEDD4L)
FCA: 
101088369(NEDD4L)
PTG: 
102951074(NEDD4L)
BTA: 
510003(NEDD4L)
BOM: 
102267387(NEDD4L)
PHD: 
102328595(NEDD4L)
CHX: 
102170194(NEDD4L)
SSC: 
CFR: 
102513659(NEDD4L)
BACU: 
103005326(NEDD4L)
LVE: 
103081012(NEDD4L)
ECB: 
100054395(NEDD4L)
MYB: 
102251438(NEDD4L)
MYD: 
102755374(NEDD4L)
PALE: 
102892677(NEDD4L)
MDO: 
100022149(NEDD4L)
SHR: 
100925489(NEDD4L)
GGA: 
374119(NEDD4L)
TGU: 
100217943(NEDD4L)
FAB: 
101811620(NEDD4L)
PHI: 
102111610(NEDD4L)
APLA: 
101800777(NEDD4L)
FPG: 
101919791(NEDD4L)
FCH: 
102056095(NEDD4L)
CLV: 
ASN: 
102377323(NEDD4L)
AMJ: 
102569398(NEDD4L)
PSS: 
102459538(NEDD4L)
CMY: 
102934363(NEDD4L)
ACS: 
PBI: 
XLA: 
399396(nedd4l)
XTR: 
448382(nedd4l)
DRE: 
559634(nedd4l)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102359976(NEDD4L)
CMK: 
103184866(nedd4l)
SMM: 
TAD: 
PIF: 
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Yang B, Kumar S
  Title
Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions.
  Journal
Cell Death Differ 17:68-77 (2010)
Reference
  Authors
Chan W, Tian R, Lee YF, Sit ST, Lim L, Manser E
  Title
Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.
  Journal
J Biol Chem 284:8185-94 (2009)

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