KEGG   ORTHOLOGY: K13377Help
Entry
K13377                      KO                                     

Name
TGFB3
Definition
transforming growth factor beta-3
Pathway
ko04010  MAPK signaling pathway
ko04060  Cytokine-cytokine receptor interaction
ko04068  FoxO signaling pathway
ko04110  Cell cycle
ko04218  Cellular senescence
ko04350  TGF-beta signaling pathway
ko04390  Hippo signaling pathway
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05140  Leishmaniasis
ko05142  Chagas disease (American trypanosomiasis)
ko05144  Malaria
ko05145  Toxoplasmosis
ko05146  Amoebiasis
ko05152  Tuberculosis
ko05161  Hepatitis B
ko05166  HTLV-I infection
ko05200  Pathways in cancer
ko05210  Colorectal cancer
ko05211  Renal cell carcinoma
ko05212  Pancreatic cancer
ko05220  Chronic myeloid leukemia
ko05225  Hepatocellular carcinoma
ko05226  Gastric cancer
ko05321  Inflammatory bowel disease (IBD)
ko05323  Rheumatoid arthritis
ko05410  Hypertrophic cardiomyopathy (HCM)
ko05414  Dilated cardiomyopathy (DCM)
Module
M00680  TGF-beta signaling
Disease
H00083  Allograft rejection
H00084  Graft-versus-host disease
H00293  Arrhythmogenic right ventricular cardiomyopathy (ARVC)
H00431  Ossification of the posterior longitudinal ligament of spine (OPLL)
H00516  Cleft lip and/or cleft palate
H00800  Loeys-Dietz syndrome (LDS)
H01385  Rienhoff syndrome
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04350 TGF-beta signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04390 Hippo signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
   04068 FoxO signaling pathway
    K13377  TGFB3; transforming growth factor beta-3
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K13377  TGFB3; transforming growth factor beta-3
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    K13377  TGFB3; transforming growth factor beta-3
   04218 Cellular senescence
    K13377  TGFB3; transforming growth factor beta-3
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K13377  TGFB3; transforming growth factor beta-3
   05210 Colorectal cancer
    K13377  TGFB3; transforming growth factor beta-3
   05212 Pancreatic cancer
    K13377  TGFB3; transforming growth factor beta-3
   05225 Hepatocellular carcinoma
    K13377  TGFB3; transforming growth factor beta-3
   05226 Gastric cancer
    K13377  TGFB3; transforming growth factor beta-3
   05220 Chronic myeloid leukemia
    K13377  TGFB3; transforming growth factor beta-3
   05211 Renal cell carcinoma
    K13377  TGFB3; transforming growth factor beta-3
  Immune diseases
   05323 Rheumatoid arthritis
    K13377  TGFB3; transforming growth factor beta-3
   05321 Inflammatiory bowel disease (IBD)
    K13377  TGFB3; transforming growth factor beta-3
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    K13377  TGFB3; transforming growth factor beta-3
   05414 Dilated cardiomyopathy (DCM)
    K13377  TGFB3; transforming growth factor beta-3
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    K13377  TGFB3; transforming growth factor beta-3
  Infectious diseases
   05152 Tuberculosis
    K13377  TGFB3; transforming growth factor beta-3
   05166 HTLV-I infection
    K13377  TGFB3; transforming growth factor beta-3
   05161 Hepatitis B
    K13377  TGFB3; transforming growth factor beta-3
   05146 Amoebiasis
    K13377  TGFB3; transforming growth factor beta-3
   05144 Malaria
    K13377  TGFB3; transforming growth factor beta-3
   05145 Toxoplasmosis
    K13377  TGFB3; transforming growth factor beta-3
   05140 Leishmaniasis
    K13377  TGFB3; transforming growth factor beta-3
   05142 Chagas disease (American trypanosomiasis)
    K13377  TGFB3; transforming growth factor beta-3
KEGG modules [BR:ko00002]
 Functional set
  Cellular processes
   Cell signaling
    M00680  TGF-beta signaling
     K13377  TGFB3; transforming growth factor beta-3
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   K13377  TGFB3; transforming growth factor beta-3
BRITE hierarchy
Genes
HSA: 7043(TGFB3)
PTR: 453054(TGFB3)
PPS: 100990987(TGFB3)
GGO: 101133741(TGFB3)
PON: 100433208(TGFB3)
NLE: 100591391(TGFB3)
MCC: 703239(TGFB3)
MCF: 102119907(TGFB3)
CSAB: 103229367(TGFB3)
RRO: 104677599(TGFB3)
RBB: 108534939(TGFB3)
CJC: 100392463(TGFB3)
SBQ: 101048819(TGFB3)
MMU: 21809(Tgfb3)
RNO: 25717(Tgfb3)
CGE: 100756831(Tgfb3)
NGI: 103739777(Tgfb3)
HGL: 101712904(Tgfb3)
CCAN: 109686152(Tgfb3)
OCU: 100358982(TGFB3)
TUP: 102497029(TGFB3)
CFA: 490796(TGFB3)
AML: 100475861(TGFB3)
UMR: 103670922(TGFB3)
ORO: 101364584(TGFB3)
FCA: 101098469(TGFB3)
PTG: 102949760(TGFB3)
AJU: 106974351(TGFB3)
BTA: 538957(TGFB3)
BOM: 102265567(TGFB3)
BIU: 109565371(TGFB3)
PHD: 102342990(TGFB3)
CHX: 102189962(TGFB3)
OAS: 554323(TGFB3)
SSC: 397400(TGFB3)
CFR: 102517948(TGFB3)
CDK: 105086078(TGFB3)
BACU: 103001029(TGFB3)
LVE: 103086562(TGFB3)
OOR: 101289027(TGFB3)
ECB: 100051765(TGFB3)
EPZ: 103555506(TGFB3)
EAI: 106830938(TGFB3)
MYB: 102249502(TGFB3)
MYD: 102767291(TGFB3)
HAI: 109381619(TGFB3)
RSS: 109448352(TGFB3)
PALE: 102893304(TGFB3)
LAV: 100653832(TGFB3)
TMU: 101358028
MDO: 100017937(TGFB3)
SHR: 100929617(TGFB3)
OAA: 100074840(TGFB3)
GGA: 396438(TGFB3)
MGP: 100544554(TGFB3)
CJO: 107315120(TGFB3)
APLA: 101802287(TGFB3)
ACYG: 106038869(TGFB3)
TGU: 100232487(TGFB3)
GFR: 102037028(TGFB3)
FAB: 101809258(TGFB3)
PHI: 102102248(TGFB3)
PMAJ: 107205526(TGFB3)
CCW: 104685280(TGFB3)
FPG: 101912650(TGFB3)
FCH: 102055453(TGFB3)
CLV: 102088125(TGFB3)
EGZ: 104133279(TGFB3)
AAM: 106482877(TGFB3)
ASN: 102384560(TGFB3)
AMJ: 102563668(TGFB3)
PSS: 102456369(TGFB3)
CMY: 102929710(TGFB3)
CPIC: 101941121(TGFB3)
ACS: 100551709(tgfb3)
PVT: 110079121(TGFB3)
PBI: 103061116(TGFB3)
GJA: 107116455(TGFB3)
DRE: 369195(tgfb3)
SRX: 107723269 107724242(tgfb3)
SANH: 107688075 107702240(tgfb3)
SGH: 107554783(tgfb3) 107589794
IPU: 108270130(tgfb3)
AMEX: 103032923(tgfb3)
TRU: 101065117(tgfb3) 101077955
LCO: 104921351(tgfb3) 104922426
OLA: 101155815 101165927(tgfb3)
XMA: 102221990(tgfb3) 102223288
PRET: 103457593 103459051(tgfb3)
NFU: 107377518 107392404(tgfb3)
LCF: 108892510(tgfb3) 108895683
HCQ: 109507757(tgfb3)
BPEC: 110153435 110155280(tgfb3)
ELS: 105015709(tgfb3) 105029941
SFM: 108930719(tgfb3) 108936661
LCM: 102358543(TGFB3)
CMK: 103174445
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3164476
  Authors
ten Dijke P, Hansen P, Iwata KK, Pieler C, Foulkes JG
  Title
Identification of another member of the transforming growth factor type beta gene family.
  Journal
Proc Natl Acad Sci U S A 85:4715-9 (1988)
  Sequence
[hsa:7043]
Reference
  Authors
Bocharov EV, Korzhnev DM, Blommers MJ, Arvinte T, Orekhov VY, Billeter M, Arseniev AS
  Title
Dynamics-modulated biological activity of transforming growth factor beta3.
  Journal
J Biol Chem 277:46273-9 (2002)
DOI:10.1074/jbc.M206274200
  Sequence
[hsa:7043]
Reference
PMID:3208746
  Authors
Derynck R, Lindquist PB, Lee A, Wen D, Tamm J, Graycar JL, Rhee L, Mason AJ, Miller DA, Coffey RJ, et al.
  Title
A new type of transforming growth factor-beta, TGF-beta 3.
  Journal
EMBO J 7:3737-43 (1988)
  Sequence
[hsa:7043]

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