KEGG   ORTHOLOGY: K13421Help
Entry
K13421                      KO                                     

Name
UMPS
Definition
uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23]
Pathway
ko00240  Pyrimidine metabolism
ko00983  Drug metabolism - other enzymes
ko01100  Metabolic pathways
Module
M00051  Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
Disease
H00198  Orotic aciduria
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    K13421  UMPS; uridine monophosphate synthetase
  Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    K13421  UMPS; uridine monophosphate synthetase
KEGG modules [BR:ko00002]
 Pathway module
  Nucleotide and amino acid metabolism
   Pyrimidine metabolism
    M00051  Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
     K13421  UMPS; uridine monophosphate synthetase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.10  orotate phosphoribosyltransferase
     K13421  UMPS; uridine monophosphate synthetase
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.23  orotidine-5'-phosphate decarboxylase
     K13421  UMPS; uridine monophosphate synthetase
BRITE hierarchy
Other DBs
RN: R00965 R01870 R08231
GO: 0004588 0004590
Genes
HSA: 7372(UMPS)
PTR: 460644(UMPS)
PPS: 100991899(UMPS)
GGO: 101124432(UMPS)
PON: 100173867(UMPS)
NLE: 100583986(UMPS)
MCC: 715664(UMPS)
MCF: 101926611(UMPS)
CSAB: 103228151(UMPS)
RRO: 104655401(UMPS)
RBB: 108517421(UMPS)
CJC: 100395639(UMPS)
SBQ: 101051574(UMPS)
MMU: 22247(Umps)
RNO: 288051(Umps)
CGE: 100756786(Umps)
NGI: 103741998(Umps)
HGL: 101699019(Umps)
CCAN: 109700921(Umps)
OCU: 100353794(UMPS)
TUP: 102472138(UMPS) 102494084
CFA: 478593(UMPS)
AML: 100474250(UMPS)
UMR: 103678747(UMPS)
ORO: 101377244(UMPS)
FCA: 101095364(UMPS)
PTG: 102970593(UMPS)
AJU: 106984097(UMPS)
BTA: 281568(UMPS)
BOM: 102268246(UMPS)
BIU: 109555944(UMPS)
PHD: 102335345(UMPS)
CHX: 102168204(UMPS)
OAS: 101116528(UMPS)
SSC: 100516340(UMPS)
CFR: 102516645(UMPS)
CDK: 105090275(UMPS)
BACU: 103010457(UMPS)
LVE: 103089316(UMPS)
OOR: 101280856(UMPS)
ECB: 100070386(UMPS)
EPZ: 103547470(UMPS)
EAI: 106847537(UMPS)
MYB: 102261895(UMPS)
MYD: 102771201(UMPS)
HAI: 109387974(UMPS)
RSS: 109441043 109451063(UMPS)
PALE: 102891815(UMPS)
LAV: 100669390(UMPS)
TMU: 101361423
MDO: 100020046(UMPS)
SHR: 100931124(UMPS)
OAA: 103166226(UMPS)
GGA: 424256(UMPS)
MGP: 100549216(UMPS)
CJO: 107316781(UMPS)
APLA: 101795395(UMPS)
ACYG: 106029902(UMPS)
TGU: 100229392(UMPS)
GFR: 102045613(UMPS)
FAB: 101810877(UMPS)
PHI: 102106605(UMPS)
PMAJ: 107207338(UMPS)
CCW: 104694024(UMPS)
FPG: 101923631(UMPS)
FCH: 102047938(UMPS)
CLV: 102096739(UMPS)
EGZ: 104128103(UMPS)
AAM: 106499181(UMPS)
ASN: 102373791(UMPS)
AMJ: 102563233(UMPS)
PSS: 102461138(UMPS)
CMY: 102947657(UMPS)
CPIC: 101952256(UMPS)
ACS: 100556619 100557538(umps)
PVT: 110090760(UMPS)
PBI: 103054247(UMPS)
GJA: 107105610(UMPS)
XLA: 494728(umps.L)
XTR: 496817(umps)
NPR: 108791268(UMPS)
DRE: 393143(umps)
SRX: 107749872(umps)
SANH: 107663913(umps)
SGH: 107577997(umps)
CCAR: 109091079(umps)
IPU: 108266445(umps)
AMEX: 103045389(umps)
LCO: 104919607(umps)
NCC: 104961998(umps)
MZE: 101472693(umps) 106676566
OLA: 101156482(umps)
XMA: 102234687(umps)
PRET: 103460502(umps)
NFU: 107390188(umps)
CSEM: 103392489(umps)
LCF: 108902828(umps)
HCQ: 109522350(umps)
BPEC: 110156172(umps)
SASA: 100380605(pyr5) 106581832
ELS: 105016153(umps)
SFM: 108927930(umps)
LCM: 102355832 102359046(UMPS)
CMK: 103176424(umps)
CIN: 100180443
SPU: 580407
APLC: 110977174
SKO: 100367421
DME: Dmel_CG3593(r-l)
DSI: Dsimw501_GD20011(Dsim_GD20011)
MDE: 101890564
AAG: 5574665
AME: 408461(GB19369)
BIM: 100740763
AEC: 105151220
ACEP: 105620030
PBAR: 105424712
HST: 105190409
CFO: 105254008
LHU: 105675693
PGC: 109859898
TCA: 662765
DPA: 109544888
NVL: 108559463
DNX: 107161831
ZNE: 110827602
FCD: 110855899
CEL: CELE_T07C4.1(umps-1)
CBR: CBG24564
BMY: Bm1_23045
CRG: 105317500
MYI: 110446856
OBI: 106884092
SHX: MS3_01755
EPA: 110234531
HMG: 100199154
AQU: 100638985
ATH: AT3G54470
CRB: 17886165
THJ: 104824191
CPAP: 110806371
CIT: 102627519
TCC: 18593861
EGR: 104455942
LJA: Lj0g3v0062759.1(Lj0g3v0062759.1) Lj0g3v0145439.1(Lj0g3v0145439.1)
FVE: 101310257
PPER: 18785298
PMUM: 103343721
PAVI: 110772616
PXB: 103961017
CSV: 101220596
CMO: 103503258
MCHA: 111011913
RCU: 8270896
JCU: 105631215
SLY: 101244927
SPEN: 107004670
SOT: 102592981
CANN: 107847867
NTA: 107765924(pyr5-6) 107794649
NSY: 104210349
NTO: 104101167
LSV: 111889392
DCR: 108210013
BVG: 104887508
NNU: 104608808
DOSA: Os01t0951200-01(Os01g0951200) Os01t0951400-01(Os01g0951400)
ATS: 109765820(LOC109765820) 109765822(LOC109765822) 109765832(LOC109765832)
ZMA: 100274407(gpm370) 100382013(si605032h02) 732794(IDP506)
MUS: 103995932
ATR: 18443733
PPP: 112280381
CRE: CHLREDRAFT_116267(PYR5)
OLU: OSTLU_19418(PYR5)
APRO: F751_6487
NCR: NCU03488(pyr-4)
NTE: NEUTE1DRAFT45649(NEUTE1DRAFT_45649)
MGR: MGG_12098
MAW: MAC_07237
MAJ: MAA_08855
CMT: CCM_05256
MBE: MBM_01766
PTE: PTT_10167
DDI: DDB_G0280041(pyr56)
DFA: DFA_07991(pyr56)
SPAR: SPRG_09695
SYG: sync_0364
SYP: SYNPCC7002_A0610(pyrF_pyrE)
CYI: CBM981_1052(pyrFE)
MAR: MAE_28380
MPK: VL20_5217
CHON: NIES4102_03760(pyrFE)
CYT: cce_0502(pyrFE)
TER: Tery_0376
GVI: glr1079
GLJ: GKIL_3117(pyrF)
ANA: alr2945
AVA: Ava_0957
CTHE: Chro_2221
CAP: CLDAP_25050(pyrF)
WCH: wcw_0336(pyrF)
RAI: RA0C_0394
RAR: RIA_2105
RAG: B739_1900
RAE: G148_1442
RAT: M949_0095
EAO: BD94_0783
ELB: VO54_01887(pyrE)
CHZ: CHSO_4232
FBA: FIC_01694
FBU: UJ101_01335(UMPS)
BBL: BLBBGE_512(pyrF)
BPI: BPLAN_128
BMM: MADAR_233(pyrF)
BCP: BLBCPU_480(pyrF)
BBG: BGIGA_125(pyrF)
BLP: BPAA_125(pyrF)
BLU: K645_2426
TAA: NMY3_02260(pyrE)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:3279416
  Authors
Suttle DP, Bugg BY, Winkler JK, Kanalas JJ
  Title
Molecular cloning and nucleotide sequence for the complete coding region of human UMP synthase.
  Journal
Proc Natl Acad Sci U S A 85:1754-8 (1988)
DOI:10.1073/pnas.85.6.1754
  Sequence
[hsa:7372]

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