KEGG   ORTHOLOGY: K13509Help
Entry
K13509                      KO                                     

Name
AGPAT1_2
Definition
lysophosphatidate acyltransferase [EC:2.3.1.51]
Pathway
ko00561  Glycerolipid metabolism
ko00564  Glycerophospholipid metabolism
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
ko04072  Phospholipase D signaling pathway
ko04975  Fat digestion and absorption
Module
M00089  Triacylglycerol biosynthesis
Disease
H00419  Congenital generalized lipodystrophy (CGL)
Brite
KEGG Orthology (KO) [BR:ko00001]
 Metabolism
  Lipid metabolism
   00561 Glycerolipid metabolism
    K13509  AGPAT1_2; lysophosphatidate acyltransferase
   00564 Glycerophospholipid metabolism
    K13509  AGPAT1_2; lysophosphatidate acyltransferase
 Environmental Information Processing
  Signal transduction
   04072 Phospholipase D signaling pathway
    K13509  AGPAT1_2; lysophosphatidate acyltransferase
 Organismal Systems
  Digestive system
   04975 Fat digestion and absorption
    K13509  AGPAT1_2; lysophosphatidate acyltransferase
KEGG modules [BR:ko00002]
 Pathway module
  Carbohydrate and lipid metabolism
   Lipid metabolism
    M00089  Triacylglycerol biosynthesis
     K13509  AGPAT1_2; lysophosphatidate acyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.51  1-acylglycerol-3-phosphate O-acyltransferase
     K13509  AGPAT1_2; lysophosphatidate acyltransferase
Lipid biosynthesis proteins [BR:ko01004]
 Phospholipid acyltransferase
  LPAAT/LPLAT
   K13509  AGPAT1_2; lysophosphatidate acyltransferase
BRITE hierarchy
Other DBs
RN: R02241 R09381
COG: COG0204
GO: 0003841
Genes
HSA: 10554(AGPAT1) 10555(AGPAT2)
PTR: 462582(AGPAT1) 748669(AGPAT2)
PPS: 100977572(AGPAT2) 100991029(AGPAT1)
GGO: 101153839(AGPAT1) 101154487(AGPAT2)
PON: 100432876(AGPAT1) 100449893(AGPAT2)
NLE: 100588358(AGPAT2) 100600403(AGPAT1)
MCC: 709753(AGPAT2) 717174(AGPAT1)
MCF: 101865968(AGPAT1) 102135852(AGPAT2)
CSAB: 103221714(AGPAT1) 103239619(AGPAT2)
RRO: 104669666(AGPAT2) 104673989(AGPAT1)
RBB: 108519889(AGPAT1) 108542907(AGPAT2)
CJC: 100401440(AGPAT2) 100412924(AGPAT1)
SBQ: 101030180(AGPAT2) 101044607(AGPAT1)
MMU: 55979(Agpat1) 67512(Agpat2)
RNO: 311821(Agpat2) 406165(Agpat1)
CGE: 100754963(Agpat2) 100758206(Agpat1)
NGI: 103724409(Agpat1) 103741218(Agpat2)
HGL: 101706478(Agpat2) 101712016(Agpat1)
CCAN: 109690408(Agpat1) 109698980(Agpat2)
OCU: 100358688(AGPAT1)
TUP: 102482776(AGPAT2) 102485189(AGPAT1)
CFA: 474857(AGPAT1) 491249(AGPAT2)
AML: 100469184(AGPAT2) 100476518(AGPAT1)
UMR: 103675286(AGPAT2) 103682278(AGPAT1)
ORO: 101380138(AGPAT2) 101382299(AGPAT1)
FCA: 101094635(AGPAT2) 101096064(AGPAT1)
PTG: 102957012(AGPAT2) 102964663(AGPAT1)
AJU: 106983492(AGPAT1) 106989564(AGPAT2)
BTA: 282137(AGPAT1) 512112(AGPAT2)
BOM: 102265165(AGPAT1) 102277646(AGPAT2)
BIU: 109566592(AGPAT2) 109576853(AGPAT1)
PHD: 102331855 102333802(AGPAT1)
CHX: 100860912(AGPAT1) 102173200(AGPAT2)
OAS: 101114511(AGPAT2) 443121(AGPAT1)
SSC: 100170768(AGPAT2) 613128(AGPAT1)
CFR: 102515113(AGPAT2) 102522717(AGPAT1)
CDK: 105090851(AGPAT1) 105105791(AGPAT2)
BACU: 102997588 103012097(AGPAT1)
OOR: 101277978(AGPAT1) 101283053(AGPAT2)
ECB: 100059501(AGPAT1) 100068797(AGPAT2)
EPZ: 103566649(AGPAT1) 103567693(AGPAT2)
EAI: 106831020(AGPAT1) 106845562(AGPAT2)
MYB: 102248796(AGPAT2) 102260060(AGPAT1)
MYD: 102759634(AGPAT2) 102768385(AGPAT1)
HAI: 109373114(AGPAT1) 109382406(AGPAT2)
RSS: 109436772(AGPAT1) 109460884(AGPAT2)
PALE: 102890008(AGPAT2) 102897143(AGPAT1)
LAV: 100658640(AGPAT2) 100665752(AGPAT1)
MDO: 100019982(AGPAT2) 100025689(AGPAT1)
SHR: 100925097(AGPAT1) 100925750(AGPAT2)
OAA: 100081509(AGPAT2) 100089235(AGPAT1)
GGA: 419941(PRR29) 770506(AGPAT1L) 772114(AGPAT2)
APLA: 101791543(AGPAT1) 101801127 101803978(AGPAT2)
TGU: 100225268(AGPAT1) 100229145(AGPAT2)
FAB: 101809630(AGPAT1) 101813123 101813443(AGPAT2) 101815252
PHI: 102101003 102105871 102106346(AGPAT1) 102114564(AGPAT2)
PMAJ: 107212080(AGPAT2) 107212842 107215046(AGPAT1)
CCW: 104688493(AGPAT2) 104695781(AGPAT1)
EGZ: 104129364(AGPAT2) 104131093(AGPAT1)
AAM: 106483771(AGPAT2) 106496109 106497448(AGPAT1)
ASN: 102375237 102388531(AGPAT2) 106723013(AGPAT1)
AMJ: 102559540 102567189(AGPAT2) 102570924(AGPAT1)
PSS: 102448805(AGPAT2)
CMY: 102936043(AGPAT2)
CPIC: 101943398(AGPAT2) 101944318(AGPAT1)
PVT: 110074910 110079649(AGPAT2) 110088056 110089782(AGPAT1)
PBI: 103052835(AGPAT2) 103058714 103059196 103061591(AGPAT1)
XLA: 108699908(agpat2.S) 108700224(agpat1.S) 447513(agpat1.L)
XTR: 100037898(agpat1) 100170486(agpat2)
NPR: 108786548(AGPAT1) 108790233(AGPAT2) 108795775
DRE: 777624(agpat2)
CCAR: 109105349
IPU: 108278901(agpat2)
AMEX: 111193896
TRU: 101079283
LCO: 104928171(agpat2)
MZE: 101480285
OLA: 101159762
XMA: 102232433
PRET: 103473378
NFU: 107374952
CSEM: 103390057
LCF: 108881030
HCQ: 109525570
BPEC: 110157445
ELS: 105015263
LCM: 102345535(AGPAT2) 102367142(AGPAT1)
CMK: 103182976(agpat2)
SPU: 576124
DSI: Dsimw501_GD17087(Dsim_GD17087) Dsimw501_GD22398(Dsim_GD22398)
AAG: 5567820
AME: 552139(GB15848) 724907(GB14444) 724951(GB10676) 724995(GB11929)
BIM: 100741980
BTER: 100650358
BMOR: 101737501 101739608 101741213(AGPAT5) 101741440(AGPAT2) 101741580(AGPAT3)
DNX: 107161346
CEL: CELE_F59F4.4(acl-1) CELE_T06E8.1(acl-2)
CBR: CBG04832(Cbr-acl-2) CBG16005(Cbr-acl-1)
BMY: Bm1_13890
MYI: 110441721
OBI: 106878776
LAK: 106172962
SHX: MS3_07010
EPA: 110246326
ADF: 107339418
HMG: 100209966
SIND: 105174862
NNU: 104612818
SCE: YDL052C(SLC1)
ERC: Ecym_2773
KMX: KLMA_60451(SLC1)
NCS: NCAS_0A02390(NCAS0A02390)
NDI: NDAI_0D04480(NDAI0D04480) NDAI_0F00220(NDAI0F00220)
TPF: TPHA_0B00910(TPHA0B00910) TPHA_0B02370(TPHA0B02370)
TBL: TBLA_0A08150(TBLA0A08150)
TDL: TDEL_0E01460(TDEL0E01460)
KAF: KAFR_0G03120(KAFR0G03120)
CAL: CAALFM_C302600CA(SLC1)
CAUR: QG37_00180
SLB: AWJ20_5112(SLC1)
NCR: NCU00168
NTE: NEUTE1DRAFT63173(NEUTE1DRAFT_63173)
MGR: MGG_11040
MAW: MAC_00405
MAJ: MAA_06056
CMT: CCM_02787
BFU: BCIN_16g02640(Bcslc1)
MBE: MBM_04438
ANI: AN6139.2
ANG: ANI_1_490104(An12g03960)
ABE: ARB_04925
TVE: TRV_05343
PTE: PTT_08466
SPO: SPAC1851.02(slc1)
CNB: CNBI2930
LBC: LACBIDRAFT_172108(LPAAT)
ABP: AGABI1DRAFT39220(AGABI1DRAFT_39220)
ABV: AGABI2DRAFT154320(AGABI2DRAFT_154320)
MGL: MGL_3009
 » show all
TaxonomyKoalaUniProt
Reference
PMID:9461603
  Authors
Aguado B, Campbell RD
  Title
Characterization of a human lysophosphatidic acid acyltransferase that is encoded by a gene located in the class III region of the human major histocompatibility complex.
  Journal
J Biol Chem 273:4096-105 (1998)
DOI:10.1074/jbc.273.7.4096
Reference
  Authors
Agarwal AK, Sukumaran S, Cortes VA, Tunison K, Mizrachi D, Sankella S, Gerard RD, Horton JD, Garg A
  Title
Human 1-acylglycerol-3-phosphate O-acyltransferase isoforms 1 and 2: biochemical characterization and inability to rescue hepatic steatosis in Agpat2(-/-) gene lipodystrophic mice.
  Journal
J Biol Chem 286:37676-91 (2011)
DOI:10.1074/jbc.M111.250449
  Sequence
[hsa:10555]

DBGET integrated database retrieval system