KEGG   ORTHOLOGY: K13574
Entry
K13574                      KO                                     
Symbol
hcxB
Name
hydroxycarboxylate dehydrogenase B [EC:1.1.1.237 1.1.1.-]
Pathway
map00350  Tyrosine metabolism
map00360  Phenylalanine metabolism
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Reaction
R01370  phenyllactate:NAD+ oxidoreductase
R01371  phenyllactate:NADP+ oxidoreductase
R03337  (R)-3-(4-hydroxyphenyl)lactate:NAD+ 2-oxidoreductase
R03339  (R)-3-(4-hydroxyphenyl)lactate:NADP+ 2-oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K13574  hcxB; hydroxycarboxylate dehydrogenase B
   00360 Phenylalanine metabolism
    K13574  hcxB; hydroxycarboxylate dehydrogenase B
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.237  hydroxyphenylpyruvate reductase
     K13574  hcxB; hydroxycarboxylate dehydrogenase B
Other DBs
COG: COG2055
GO: 0047995
Genes
ECO: b0801(hcxB)
ECJ: JW0786(ybiC)
ECD: ECDH10B_0869(ybiC)
EBW: BWG_0654(ybiC)
ECOK: ECMDS42_0651(ybiC)
ECOC: C3026_05055
ECE: Z1022(ybiC)
ECS: ECs_0879(ybiC)
ECF: ECH74115_0950
ETW: ECSP_0898(ybiC)
ELX: CDCO157_0857
EOI: ECO111_0862(ybiC)
EOJ: ECO26_0924(ybiC)
EOH: ECO103_0837(ybiC)
ECOO: ECRM13514_0878(ybiC)
ECOH: ECRM13516_0833(ybiC)
ESL: O3K_17345
ESO: O3O_07945
ESM: O3M_17315
ECK: EC55989_0845(ybiC)
ECG: E2348C_0753(ybiC)
EOK: G2583_1029(ybiC)
ELR: ECO55CA74_04995
ELH: ETEC_0868
ECW: EcE24377A_0869
EUN: UMNK88_841
ECP: ECP_0815
ENA: ECNA114_0734(ybiC)
ECOS: EC958_0914(ybiC)
ECV: APECO1_1289(ybiC)
ECOA: APECO78_07675
ECX: EcHS_A0856
ECM: EcSMS35_0825
ECY: ECSE_0857
ECR: ECIAI1_0839(ybiC)
ECQ: ECED1_0766(ybiC)
EUM: ECUMN_0945(ybiC)
ECT: ECIAI39_0778(ybiC)
EOC: CE10_0822(ybiC)
EBR: ECB_00768(ybiC)
ECOB: C3029_08270
EBL: ECD_00768(ybiC)
EBE: B21_00785(ybiC)
EBD: ECBD_2822
ECI: UTI89_C0804(ybiC)
EIH: ECOK1_0804
ECZ: ECS88_0819(ybiC)
ECC: c0885(ybiC)
ELO: EC042_0891
ELN: NRG857_03580
ESE: ECSF_0727
ECL: EcolC_2842
EKO: EKO11_3085
EKF: KO11_19775(ybiC)
EAB: ECABU_c08430(ybiC)
EDH: EcDH1_2841
EDJ: ECDH1ME8569_0754(ybiC)
ELU: UM146_13640
ELW: ECW_m0857(ybiC)
ELL: WFL_04165(ybiC)
ELC: i14_0850(ybiC)
ELD: i02_0850(ybiC)
ELP: P12B_c0790(ybiC)
ELF: LF82_2638(ybiC)
ECOL: LY180_04220
ECOI: ECOPMV1_00803(ybiC)
ECOJ: P423_03975
EFE: EFER_2307(ybiC)
EAL: EAKF1_ch0669c
EMA: C1192_08315
ESZ: FEM44_18510
ERUY: OSH18_05715
SFL: SF0751(ybiC)
SFX: S0792(ybiC)
SFV: SFV_0784(ybiC)
SFE: SFxv_0817(ybiC)
SFN: SFy_1020
SFS: SFyv_1062
SFT: NCTC1_00758(ybiC)
SSN: SSON_0780(ybiC)
SBO: SBO_0689(ybiC)
SBC: SbBS512_E2551
SDY: SDY_0798(ybiC)
SDZ: Asd1617_01003
SHQ: A0259_07955
KPN: KPN_02089
KPU: KP1_3177
KPM: KPHS_30690
KPP: A79E_2154
KPH: KPNIH24_13095
KPZ: KPNIH27_14700
KPV: KPNIH29_15355
KPW: KPNIH30_15635
KPY: KPNIH31_14490
KPG: KPNIH32_15530
KPC: KPNIH10_15160
KPQ: KPR0928_15135
KPT: VK055_0373
KPO: KPN2242_13400
KPR: KPR_2631(ybiC)
KPJ: N559_2201
KPI: D364_10710
KPA: KPNJ1_02376
KPS: KPNJ2_02334
KPX: PMK1_04453(ybiC)
KPB: FH42_06540
KPNE: KU54_010985
KPNU: LI86_10940
KPNK: BN49_3194(ybiC)
KVA: Kvar_2185
KPE: KPK_2241
KPK: A593_25410
KVD: KR75_23335
KVQ: SP68_04050
KOX: KOX_18735 KOX_22540
KOE: A225_2618 A225_3382
KOY: J415_15110 J415_18885
KOM: HR38_17100 HR38_20840
KOK: KONIH1_12525 KONIH1_16575
KOC: AB185_19325
KQU: AVR78_19520
EAE: EAE_17445
EAR: CCG30404
KQV: B8P98_11955
KLL: BJF97_16700
KLW: DA718_12245
KAR: LGL98_10470
KGR: JJJ10_12210
KPAS: LUW96_23190
KLC: K7H21_11925
KLM: BWI76_16775
REE: electrica_01980(ybiC_1) electrica_02154(ybiC_2)
ROR: RORB6_04420
RON: TE10_17060
RPLN: B1209_11075
RAO: DSD31_10850
RTG: NCTC13098_02582(ybiC_1) NCTC13098_03134(ybiC_2)
CKO: CKO_02080
CFD: CFNIH1_14120
CBRA: A6J81_08975
CWE: CO701_14780
CYO: CD187_16155
CPOT: FOB25_03655
CFQ: C2U38_08175
CIF: AL515_08610
CIE: AN232_22325
CPAR: CUC49_03815
CITZ: E4Z61_00990
CARS: E1B03_09210
CIX: M4I31_15600
CIB: HF677_015760
CEM: LH23_17850
PGE: LG71_13660
KOR: AWR26_07420
KRD: A3780_16540
SYM: K6K13_11430
AHN: NCTC12129_02563(ybiC)
ASUB: NLZ15_11070
KIN: AB182_12390 AB182_18530
PDZ: HHA33_15075 HHA33_21005
METY: MRY16398_29140(ybiC) MRY16398_42030
IZH: FEM41_12230
EBC: C2U52_23280 C2U52_29745
EBU: CUC76_00540
PSTS: E05_07330
SMAR: SM39_1490
SMAC: SMDB11_1291
SMW: SMWW4_v1c20410(ybiC)
SPE: Spro_2010
SRR: SerAS9_1961
SRL: SOD_c18420(ybiC)
SRY: M621_10145
SPLY: Q5A_010085(ybiC)
SRS: SerAS12_1961
SRA: SerAS13_1962
SMAF: D781_1855
SLQ: M495_09840
SRZ: AXX16_3279
SERM: CLM71_09250
SQU: E4343_06090
SFJ: SAMEA4384070_2085(ybiC_2)
SOF: NCTC11214_04882(ybiC)
SSUR: ATE40_006730
SURI: J0X03_13805
SRHZ: FO014_00575
SENP: KHA73_10260
SNEM: NLX84_10280
GQU: AWC35_00900 AWC35_03550
PROD: PCO85_12655
SERA: Ser39006_011830
SERQ: CWC46_11825
ECA: ECA1527
PATR: EV46_07725
PATO: GZ59_15650
PCT: PC1_1400 PC1_1845
PCC: PCC21_019060
PCV: BCS7_07065
PWA: Pecwa_1798 Pecwa_2132
PPAR: A8F97_08210 A8F97_09785
PEC: W5S_1712 W5S_2077
PWS: A7983_18130 A7983_22515
PPOA: BJK05_02250 BJK05_04260
PBRA: B5S52_12455
PPUJ: E2566_09885
PARI: I2D83_10070 I2D83_14995
PVZ: OA04_24140 OA04_28810
PPOO: LW347_07580 LW347_09670
PCAC: OI450_10325
PACB: M9782_09525 M9782_11760
DDD: Dda3937_02253 Dda3937_02692
DZE: Dd1591_1632
DDC: Dd586_1595
DZC: W909_12045
DSO: A4U42_00945 A4U42_16640
CED: LH89_04530 LH89_21165
DFN: CVE23_08230 CVE23_13820
DDQ: DDI_1237 DDI_2492
DAQ: DAQ1742_02832
DIC: Dpoa569_001506 Dpoa569_002383
DLC: O1Q98_04280
DDA: Dd703_1300 Dd703_1601
BGJ: AWC36_08580 AWC36_10535
BRB: EH207_11335
BNG: EH206_12170 EH206_14470
BIZ: HC231_09955
LBQ: CKQ53_11480
LPOP: I6N93_06705
SLIG: GTU79_18870
EPE: CI789_12735
ERP: LJN55_06005
PAO: Pat9b_1046
KLN: LH22_16995
PANS: FCN45_05475
KPIE: N5580_12825
PPHO: CTZ24_05400
TCI: A7K98_05900
GAI: IMCC3135_12715(ybiC)
LLP: GH975_03415
PSE: NH8B_1101
VOG: LCH97_00155
LHK: LHK_00733
MAER: DAI18_01965
RPJ: N234_10685
REH: H16_B0942(h16_B0942)
CNC: CNE_2c09100
CUH: BJN34_25865
REU: Reut_A1498
RME: Rmet_1634(ybiC)
CTI: RALTA_B0766
CBW: RR42_s1740
CGD: CR3_3549(ybiC)
CCUP: BKK81_30325
CUP: BKK80_26030
CUU: BKK79_31905
CPAU: EHF44_13540
COX: E0W60_18040
CCAM: M5D45_08140
CCAX: KZ686_03800
CUK: KB879_09545
CNAN: A2G96_27955
BVI: Bcep1808_5437
BVE: AK36_3467
BUR: Bcep18194_B0783
BCM: Bcenmc03_5376
BCH: Bcen2424_4910
BCJ: BCAM2148
BCEN: DM39_5704
BCEW: DM40_4867
BCEO: I35_6030
BAM: Bamb_4341
BAC: BamMC406_4858
BMJ: BMULJ_04813(ybiC)
BMU: Bmul_3704
BMK: DM80_5086
BMUL: NP80_4847
BCT: GEM_3531
BCED: DM42_5847
BCEP: APZ15_28390
BDL: AK34_3599
BPYR: ABD05_24720
BCON: NL30_01730 NL30_16180
BDF: WI26_23635
BLAT: WK25_26805
BTEI: WS51_07850
BSEM: WJ12_30605
BPSL: WS57_03400
BMEC: WJ16_29210
BSTG: WT74_29735
BSTL: BBJ41_24285
BANN: JFN94_28665
BARI: NLX30_26670
BAEN: L3V59_24980
BUG: BC1001_3756
BYI: BYI23_B006540
BUK: MYA_5051
BUE: BRPE67_BCDS08850
BUQ: AC233_20755
BUM: AXG89_21570
BUI: AX768_24100
BURK: DM992_22225
BPH: Bphy_5277
BGE: BC1002_4042
BPX: BUPH_00322
BPY: Bphyt_5456
BCAI: K788_0002937
PSPW: BJG93_25975
PARA: BTO02_06355
PHS: C2L64_24685
PTER: C2L65_23600
PGP: CUJ91_22670
PCJ: CUJ87_22265
PTS: CUJ90_29855
PMEG: FNZ07_00650
PGIS: I6I06_23935
PACP: FAZ97_24460
PACS: FAZ98_22870
PEW: KZJ38_17700
PSAA: QEN71_10905
CABA: SBC2_58360(hcxB)
BUO: BRPE64_BCDS06860(ybiC)
CABK: NK8_35440
TVL: FAZ95_33500
BFZ: BAU07_03380
BOZ: DBV39_18870
ODH: DHf2319_09600
RHY: RD110_04390
RHF: EUB48_18815
POL: Bpro_3968
POS: DT070_03385
PVAC: HC248_02881(hcxB_2)
VEI: Veis_1530
VAP: Vapar_0782
VPE: Varpa_0800
VPD: VAPA_1c08430
VAA: AX767_07380
VBO: CKY39_03955
VAM: C4F17_15290
CTEZ: CT3_36280
RTA: Rta_08970
LIM: L103DPR2_00626(ybiC)
LIH: L63ED372_02625(ybiC)
SUTT: SUTMEG_20000
SUTK: FG381_06190
SWS: I6J16_00030
MLO: mlr9117
BJA: bll2917(bll2917)
BJU: BJ6T_67890 BJ6T_68480
BJP: RN69_32930 RN69_33220
BRA: BRADO2597
BBT: BBta_2943
BRS: S23_50980
AOL: S58_50150
BRC: BCCGELA001_13060 BCCGELA001_13315
BRAD: BF49_1720 BF49_1774
BIC: LMTR13_28430
BRO: BRAD285_4739
BRK: CWS35_18135
BOT: CIT37_39020
BRQ: CIT40_09065
BGQ: X265_26365
BGZ: XH91_24600
BSYM: CIT39_08165 CIT39_08460
BBET: F8237_05505
BARH: WN72_16000
BVZ: BRAD3257_5784(ybiC)
BEL: BE61_70620
BDG: LPJ38_17615 LPJ38_17875
BSEP: HAP48_0030810
BQB: J4P68_0032070
BSEI: KMZ68_09630
BBAN: J4G43_016705 J4G43_016990
BCAN: BcanWSM471_13885 BcanWSM471_14145
BAUT: QA635_28615
BBRA: QA636_30500
BGK: IC762_11620
BCOU: IC761_24805
BPAH: QA639_15380
BXN: I3J27_10905
BROS: QUH67_11825 QUH67_30270
BRAZ: LRP30_12450
RPA: TX73_019450
RPB: RPB_1710
RPC: RPC_1699
RPD: RPD_3587
RPT: Rpal_4277
RPX: Rpdx1_1587
RBK: E0H22_18025
VGO: GJW-30_1_02181(ybiC)
TRB: HB776_13875
TALZ: RPMA_20140
BOP: AXW83_07660
BOS: BSY19_2656
BVV: BHK69_19355
BOI: BLM15_06645
BOF: FQV39_04075
BVES: QO058_00810
STAR: G3545_25755
MRD: Mrad2831_3061
MET: M446_6488
MNO: Mnod_6588
MOR: MOC_3439
MAQU: Maq22A_c16540
MPHY: MCBMB27_02475
MEE: DA075_22540
METX: A3862_16640
MMES: MMSR116_15560
MTEA: DK419_16250
MIND: mvi_46040
MTAD: M6G65_32955
MOC: BB934_16735
RHJ: HZY79_01380
PSIN: CAK95_00185
RBM: TEF_07945 TEF_09375
PHR: C6569_08080
PSTG: E8M01_33730
PAQT: E8L99_16820
SIL: SPO1603
LEJ: ETW24_04545
SPOT: G6548_05185
TSCO: R1T40_21920
MMR: Mmar10_0711
HYT: HXX25_01495
ZMP: Zymop_1077
RGI: RGI145_06295
ROS: CTJ15_11105
RMUC: FOB66_08110
RMT: IAI58_14260
RFL: Rmf_01580 Rmf_44780
RCV: PFY06_16565
SRF: LHU95_03030 LHU95_11910
RAP: RHOA_0566(hcxB) RHOA_1359(hcxB)
SHUM: STHU_18420 STHU_40300 STHU_51190
SVC: STVA_34900 STVA_51100
STEL: STAQ_17320 STAQ_46330
AZL: AZL_a00760 AZL_a06180
ALI: AZOLI_p20546
ABS: AZOBR_p130099(ldh)
ABQ: ABAZ39_18425
ABF: AMK58_16305
ATI: AL072_27750
AZT: TSH58p_29005
AZM: DM194_19645 DM194_22170
AZZ: DEW08_01245
AARE: D3093_15450
AZS: E6C72_16090 E6C72_23440
SKT: IGS68_02365
SMUC: JL100_002470
SROE: JL101_023045
FER: FNB15_01600
ELIO: KO353_01085 KO353_03675 KO353_05605
NACI: NUH88_01885 NUH88_11400
THAR: T8K17_02885 T8K17_19110
TMO: TMO_0662(ybiC)
HFL: PUV54_01395
SNEA: NBZ79_18745
ASOI: MTP13_14750
DNI: HX89_07150
ARS: ADJ73_10745
PDX: Psed_6328
VER: HUT12_13325
PSUU: Psuf_086470
HALG: HUG10_07180
 » show all
Reference
PMID:8037924
  Authors
Ohmori H
  Title
Structural analysis of the rhlE gene of Escherichia coli.
  Journal
Jpn J Genet 69:1-12 (1994)
DOI:10.1266/jjg.69.1
  Sequence
[eco:b0801]
Reference
PMID:27941785
  Authors
Sevin DC, Fuhrer T, Zamboni N, Sauer U
  Title
Nontargeted in vitro metabolomics for high-throughput identification of novel enzymes in Escherichia coli.
  Journal
Nat Methods 14:187-194 (2017)
DOI:10.1038/nmeth.4103
  Sequence
[eco:b0801]

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Ontology (4)   
   KEGG BRITE (2)   
   GO (1)   
   COG (1)   
Pathway (8)   
   KEGG PATHWAY (8)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
   KEGG RCLASS (1)   
Gene (5275)   
   KEGG GENES (517)   
   KEGG MGENES (3655)   
   RefGene (1097)   
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Literature (2)   
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